Align cobalamin-dependent methionine synthase (EC 2.1.1.13) (characterized)
to candidate WP_011319793.1 AVA_RS15430 methionine synthase
Query= metacyc::G18NG-11090-MONOMER
(1221 letters)
>NCBI__GCF_000204075.1:WP_011319793.1
Length = 1178
Score = 994 bits (2571), Expect = 0.0
Identities = 550/1229 (44%), Positives = 764/1229 (62%), Gaps = 67/1229 (5%)
Query: 5 VTSPAHNNAHSSEFLDALANHVLIGDGAMGTQLQGFDLDVEKDF--LDLEGCNEILNDTR 62
+T P HS EF V++ DGAMGT LQ +L E DF + EGCNE L T+
Sbjct: 1 MTHPFLKRLHSPEF------PVIVFDGAMGTNLQTQNLTAE-DFGGVQYEGCNEYLVHTK 53
Query: 63 PDVLRQIHRAYFEAGADLVETNTFGCNLPNLADYDIADRCRELAYKGTAVAREVADEMGP 122
P+ + ++HR + GAD++ET+TFG LA+YD+AD+ L K +A+ VA E
Sbjct: 54 PEAVAKVHRDFLAVGADVIETDTFGATSIVLAEYDLADQTYYLNKKAAELAKSVAAEFST 113
Query: 123 GRNGMRRFVVGSLGPGTKLPSLGHAPYADLRGHYKEAALGIIDGGGDAFLIETAQDLLQV 182
RFV GS+GP TKLP+LGH + L+ + E A ++DGG D L+ET QD+LQ+
Sbjct: 114 PDKP--RFVAGSIGPTTKLPTLGHIDFDTLKTAFAEQAEALLDGGVDLLLVETCQDVLQI 171
Query: 183 KAAVHGVQDAMAELDTFLPIICHVTVETTGTMLMGSEIGAALTALQPLGIDMIGLNCATG 242
KAA++G+++ A+ +P++ VT+E+ GTML+GSEI A LT L+P ID++GLNCATG
Sbjct: 172 KAALNGIEEVFAKRGERIPLMVSVTMESMGTMLVGSEINAVLTILEPFPIDILGLNCATG 231
Query: 243 PDEMSEHLRYLSKHADIPVSVMPNAGLPVLGKNGAEYPLEAEDLAQALAGFVSEYGLSMV 302
PD M H++YL++H+ VS +PNAGLP A Y L +L AL FV + G+ ++
Sbjct: 232 PDLMKPHIKYLAEHSPFVVSCIPNAGLPENVGGQAHYRLTPMELRMALMHFVEDLGVQVI 291
Query: 303 GGCCGTTPEHIRAVRDAVVGVPEQETSTLTKIPAGPVEQASREVEKEDSVASLYTSVPLS 362
GGCCGT PEHI+ + + A ++ R+ E + AS+Y++
Sbjct: 292 GGCCGTRPEHIQQLAEI----------------AKDLKPKVRQPSLEPAAASIYSTQTYE 335
Query: 363 QETGISMIGERTNSNGSKAFREAMLSGDWEKCVDIAKQQTRDGAHMLDLCVDYVGRDGTA 422
Q+ ++GER N++GSK R+ + + DW+ V +A+ Q ++GAH+LD+ VDYVGRDG
Sbjct: 336 QDNSFLIVGERLNASGSKKCRDLLNAEDWDGLVSMARSQVKEGAHILDVNVDYVGRDGVR 395
Query: 423 DMATLAALLATSSTLPIMIDSTEPEVIRTGLEHLGGRSIVNSVNFEDGDGPESRYQRIMK 482
DM L + + + TLP+M+DSTE E + GL+ GG+ ++NS N+EDG E R+ ++++
Sbjct: 396 DMHELVSRIVNNVTLPLMLDSTEWEKMEAGLKVAGGKCLLNSTNYEDG---EPRFLKVLE 452
Query: 483 LVKQHGAAVVALTIDEEGQARTAEHKVRIAKRLIDDITGSYGLDIKDIVVDCLTFPISTG 542
L K++GA VV TIDEEG ARTAE K +IA+R YG+ +I D L PISTG
Sbjct: 453 LAKKYGAGVVIGTIDEEGMARTAEKKFQIAQRAYRQAV-EYGIPPTEIFFDTLALPISTG 511
Query: 543 QEETRRDGIETIEAIRELKKLYPEIHTTLGLSNISFGLNPAARQVLNSVFLNECIEAGLD 602
EE R +G TIE+I +++ P H LG+SNISFGL+PA+R VLNSVFL+E AG+D
Sbjct: 512 IEEDRENGKATIESISRIRQQLPGCHVILGVSNISFGLSPASRMVLNSVFLHEATAAGMD 571
Query: 603 SAIAHSSKILPMNRIDDRQREVALDMVYDRRTED-----YDPLQEFMQLFEGVSAADAKD 657
+AI +SKILP+++I+DR +EV ++YD+R D YDPL E +LFEGV+ K
Sbjct: 572 AAIVSASKILPLSKIEDRHQEVCRQLIYDQRQFDGDVCIYDPLTELTKLFEGVTTKRNKG 631
Query: 658 ARAEQLAAMPLFERLAQRIIDGDKNGLEDDLEAGMKEKSPIAIINEDLLNGMKTVGELFG 717
++P+ ERL + IIDG++ GLE L +++ P+ IIN LL+GMK VGELFG
Sbjct: 632 VD----ESLPIEERLKRHIIDGERIGLEAQLTKALEQYPPLEIINTFLLDGMKVVGELFG 687
Query: 718 SGQMQLPFVLQSAETMKTAVAYLEPFMEEEAEATGSAQAEGKGKIVVATVKGDVHDIGKN 777
SGQMQLPFVLQSAETMK AVAYLEPFME+ + KGK+++ATVKGDVHDIGKN
Sbjct: 688 SGQMQLPFVLQSAETMKAAVAYLEPFMEKSESGNNA-----KGKVIIATVKGDVHDIGKN 742
Query: 778 LVDIILSNNGYDVVNLGIKQPLSAMLEAAEEHKADVIGMSGLLVKSTVVMKENLEEMNNA 837
LVDIILSNNGY V+NLGIKQP+ ++EA +HKAD I MSGLLVKST MKENLE N
Sbjct: 743 LVDIILSNNGYKVINLGIKQPVENIIEAYNQHKADCIAMSGLLVKSTAFMKENLEVFNEK 802
Query: 838 GASNYPVILGGAALTRTYVENDLNEVYTGEVYYARDAFEGLRLMDEVMAEKRGEGLDP-- 895
G N PVILGGAALT +V D Y G+V Y +DAF L MD++M K D
Sbjct: 803 GI-NVPVILGGAALTPKFVHKDCQNTYKGKVIYGKDAFSDLHFMDKLMPAKATGKWDNFL 861
Query: 896 ---NSPEAIEQAKKKAERKARNERSRKIAAERKANAAPVIVPERSDVSTDTPTAAPPFWG 952
+ E E ++ N +S + PV V+ D P PPFWG
Sbjct: 862 GFLDEVETEETEPTNSQSPVPNSQS---PVPSPQSPVPVDTRRSEAVAVDIPRPTPPFWG 918
Query: 953 TRIVK--GLPLAEFLGNLDERALFMGQWGLKSTRGNEGPSYEDLVETEGRPRLRYWLDRL 1010
T++++ + L E ++D +AL GQW + + Y+ + + P L W R+
Sbjct: 919 TQLLQPSDISLEEIFWHMDLQALVAGQWQFRKPKEQSKEEYQAFLNEQVYPILETWKQRI 978
Query: 1011 KSEGILDHVALVYGYFPAVAEGDDVVILESPDPHAAERMRFSFPRQQRGRFLCIADFIRP 1070
+E +L H ++YGYFP +EG+ + + +S P+A E +F FPRQ+ R LCIADF P
Sbjct: 979 IAENLL-HPQVIYGYFPCQSEGNTLYVYDSNSPNAKEITQFEFPRQKSSRRLCIADFFAP 1037
Query: 1071 REQAVKDGQVDVMPFQLVTMGNPIADFANELFAANEYREYLEVHGIGVQLTEALAEYWHS 1130
++ G +DV P Q VT+G+ +FA +LFA N+Y +YL HG+ VQ+ EALAE+ H+
Sbjct: 1038 KD----SGIIDVFPMQAVTVGDIATEFAQKLFANNQYTDYLYFHGLAVQVAEALAEWTHA 1093
Query: 1131 RVRSELKLNDGGSVADFDPEDKTKFFDLDYRGARFSFGYGSCPDLEDRAKLVELLEPGRI 1190
R+R EL G A+ +P++ Y+G+R+SFGY +CP+++D+ K ++LLE RI
Sbjct: 1094 RIRREL-----GFGAE-EPDNIRDILAQRYQGSRYSFGYPACPNIQDQFKQLDLLETSRI 1147
Query: 1191 GVELSEELQLHPEQSTDAFVLYHPEAKYF 1219
+ + E QL+PEQST A + YHP AKYF
Sbjct: 1148 NLYMDESEQLYPEQSTTAIITYHPVAKYF 1176
Lambda K H
0.316 0.135 0.386
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 1
Number of Hits to DB: 3198
Number of extensions: 157
Number of successful extensions: 17
Number of sequences better than 1.0e-02: 1
Number of HSP's gapped: 1
Number of HSP's successfully gapped: 1
Length of query: 1221
Length of database: 1178
Length adjustment: 47
Effective length of query: 1174
Effective length of database: 1131
Effective search space: 1327794
Effective search space used: 1327794
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 59 (27.3 bits)
Align candidate WP_011319793.1 AVA_RS15430 (methionine synthase)
to HMM TIGR02082 (metH: methionine synthase (EC 2.1.1.13))
../bin/blast/fastacmd -i /tmp/list.10636.in -d ../tmp/orgsDef_201/orgs.faa -p T > /tmp/gapView.10636.genome.faa failed: Inappropriate ioctl for device at ../lib/pbutils.pm line 379.
For help, please send mail to the webmaster (help@microbesonline.org), giving this error message and the time and date of the error.