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Align NP_001247015.1 to PF12130 (DUF3585)

NP_001247015.1 has 4743 amino acids

Query:       DUF3585  [M=136]
Accession:   PF12130.8
Description: Bivalent Mical/EHBP Rab binding domain
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence       Description
    ------- ------ -----    ------- ------ -----   ---- --  --------       -----------
    2.6e-27   81.8  14.9    2.6e-27   81.8  14.9    4.2  4  NP_001247015.1  


Domain annotation for each sequence (and alignments):
>> NP_001247015.1  
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ?   -4.6   5.6         1         1      68     108 ..       5      47 ..       1      55 [. 0.74
   2 ?   -4.5   1.5         1         1      72      84 ..     816     828 ..     792     843 .. 0.56
   3 ?   -4.7   0.9         1         1      59      95 ..    1971    2008 ..    1962    2024 .. 0.52
   4 !   81.8  14.9   2.6e-27   2.6e-27       1     119 [.    4583    4706 ..    4583    4717 .. 0.96

  Alignments for each domain:
  == domain 1  score: -4.6 bits;  conditional E-value: 1
         DUF3585  68 eqeLedeqadl..eqelrelmakeekeKteedkereeelleel 108
                      q+  +++ +l   q+ ++ m +++++ t ++++++++l++e 
  NP_001247015.1   5 HQRHHQQHHHLppHQQPQQQMPQQQQQLTAQQQQQQQLLMAEH 47 
                     5555566666644577788899999999999999999999885 PP

  == domain 2  score: -4.5 bits;  conditional E-value: 1
         DUF3585  72 edeqadleqelre 84 
                     +++ +++e++ +e
  NP_001247015.1 816 QQRLQEIEENRQE 828
                     2222233333333 PP

  == domain 3  score: -4.7 bits;  conditional E-value: 1
         DUF3585   59 eseLmil.areqeLedeqadleqelrelmakeekeKte 95  
                       + L+ +     +Le+  + l++e r+  +   ++K +
  NP_001247015.1 1971 RESLVSVsDSMSDLEKTMDYLRNEWRNEATNFLQKKRD 2008
                      44444441445567777777777776654443333333 PP

  == domain 4  score: 81.8 bits;  conditional E-value: 2.6e-27
         DUF3585    1 iqreleeieeeqreleergvelEkaLRgea....e.esgeeeeeellqewfeLvneknelvrreseLmilareqeLedeqadleqelrelmak 88  
                      iqre eeie+++++le+rgv +EkaLRgea    + + +++++e+ll+e++e++++  +l +r++eL+i ++e++Le ++a+l++el+ ++++
  NP_001247015.1 4583 IQREQEEIEVQLKDLEARGVLIEKALRGEAqnieNlDATKDNDEKLLKELLEIWRNITALKKRDEELTIRQQELQLEYRHAQLKEELNLRLSC 4675
                      8****************************9999967889999*************************************************** PP

         DUF3585   89 eekeKteedkereeelleelvevVeqRdelv 119 
                      ++ +K+++d ++e  +l+e++e+V +R +l 
  NP_001247015.1 4676 NKLDKSSADVAAEGAILNEMLEIVAKRAALR 4706
                      ***************************9985 PP



Or compare NP_001247015.1 to CDD or PaperBLAST