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Align NP_002102.4 to PF12372 (Htt_N-HEAT)

NP_002102.4 has 3144 amino acids

Query:       Htt_N-HEAT  [M=851]
Accession:   PF12372.12
Description: Huntingtin, N-terminal HEAT
Scores for complete sequences (score includes all domains):
   --- full sequence ---   --- best 1 domain ---    -#dom-
    E-value  score  bias    E-value  score  bias    exp  N  Sequence    Description
    ------- ------ -----    ------- ------ -----   ---- --  --------    -----------
          0 1096.4   5.6          0 1095.2   5.6    1.6  1  NP_002102.4  


Domain annotation for each sequence (and alignments):
>> NP_002102.4  
   #    score  bias  c-Evalue  i-Evalue hmmfrom  hmm to    alifrom  ali to    envfrom  env to     acc
 ---   ------ ----- --------- --------- ------- -------    ------- -------    ------- -------    ----
   1 ! 1095.2   5.6         0         0       1     850 [.     758    1633 ..     758    1634 .. 0.97

  Alignments for each domain:
  == domain 1  score: 1095.2 bits;  conditional E-value: 0
   Htt_N-HEAT    1 yanhsDpqlrgvvllllekfikavlsqqvllyerwlqslesiknrkaqdldalvklllkgLkdessgtlrlaisavesClrnLadSkeflqlLqll 96  
                   y +h Dpq+rg++++l++++i ++ls+++ ++++w+ ++++ ++ ++++l +++ ll k+Lkdess+t++la++av+ C+ +L++S++++++Lql+
  NP_002102.4  758 YIDHGDPQVRGATAILCGTLICSILSRSRFHVGDWMGTIRTLTG-NTFSLADCIPLLRKTLKDESSVTCKLACTAVRNCVMSLCSSSYSELGLQLI 852 
                   679***************************************99.9************************************************** PP

   Htt_N-HEAT   97 iellalktsaywlvkvellellaklkyvlve..............nitassrlqervldsvliallqdedprvrsaaaaaivkaipkLfyktrs.e 177 
                   i++l l +s+ywlv++elle+la+++++lv+              ++t+  +lqervl++v+i+ll+dedprvr++aaa +++++pkLfyk+++ +
  NP_002102.4  853 IDVLTLRNSSYWLVRTELLETLAEIDFRLVSfleakaenlhrgahHYTGLLKLQERVLNNVVIHLLGDEDPRVRHVAAASLIRLVPKLFYKCDQgQ 948 
                   ************************************************************************************************ PP

   Htt_N-HEAT  178 edeitakAkelsekllscltellveleshd..slisaaskayslLakrsnvcrtkdalesslSrivcklselLlvsaskalllgCleallalsley 271 
                   +d ++a+A+++s+ +l+ l++ ++   sh   s+i++++++y lL +      t+ ++e++lSr+++++s++L++s+++al++gC+eal+ ls ++
  NP_002102.4  949 ADPVVAVARDQSSVYLKLLMHETQP-PSHFsvSTITRIYRGYNLLPS-----ITDVTMENNLSRVIAAVSHELITSTTRALTFGCCEALCLLSTAF 1038
                   ********************66644.33335799*************.....6888**************************************** PP

   Htt_N-HEAT  272 pvalyekaWgckvksklkrdasvakdesaqqvelgllslvlsLLsssylnfdltaHldlLilagnLlagaalrnik...lsdsepsk........W 356 
                   pv+ ++ +W+c v+      + +a+des++++++g++ ++l+LLss+++++dl+aH+d+LilagnLla++a ++++   +s++e           W
  NP_002102.4 1039 PVCIWSLGWHCGVP------PLSASDESRKSCTVGMATMILTLLSSAWFPLDLSAHQDALILAGNLLAASAPKSLRsswASEEEANPaatkqeevW 1128
                   *************8......99******************************************************998777765446788999** PP

   Htt_N-HEAT  357 dalsdtvlvrlaeqllrhvlrllnilaevlddvtpgqatkdalpslqalqvlSplkrlkeeekkekepserlarrqssparngi............ 440 
                   +al d+ lv+++eql++h+l+++ni+a+vlddv+pg+a+k+alpsl+++++lSp++r    + kekep+e+ +  + sp++  +            
  NP_002102.4 1129 PALGDRALVPMVEQLFSHLLKVINICAHVLDDVAPGPAIKAALPSLTNPPSLSPIRR----KGKEKEPGEQASV-PLSPKKGSEasaasrqsdtsg 1219
                   *********************************************************....9********9996.8888777778889999999** PP

   Htt_N-HEAT  441 ...vakkeslGsFlhvphylrlyeiLkaaysnYkvtLaggeaedkfaslLlkdLevfsqllelAtlqedgkiaeevLmylkleiqsepkatvrcvq 533 
                      ++k++slGsF+h+p+yl+l+++Lka+++nYkvtL+ +++++kf ++L+++L+v+sq+lelAtlq++gk++ee+L+ylk+++++ep++++ cvq
  NP_002102.4 1220 pvtTSKSSSLGSFYHLPSYLKLHDVLKATHANYKVTLDLQNSTEKFGGFLRSALDVLSQILELATLQDIGKCVEEILGYLKSCFSREPMMATVCVQ 1315
                   *999******************************************************************************************** PP

   Htt_N-HEAT  534 qLLksLFgtNlasnls.....pskqearllRealagslaamlsgfyhkifqhPlarvsealrvansss.skvqaeeeae...wlgllkkkslkvar 620 
                   qLLk+LFgtNlas+++     psk++ r++R   ++s+   ++g+yh++f++P++++++al  a++s  ++vqae+e++   w+++l+k+s + ++
  NP_002102.4 1316 QLLKTLFGTNLASQFDglssnPSKSQGRAQR-LGSSSV---RPGLYHYCFMAPYTHFTQAL--ADASLrNMVQAEQENDtsgWFDVLQKVSTQLKT 1405
                   *******************************.889999...9*******************..8888889********99**************** PP

   Htt_N-HEAT  621 klaavlkgvrndektilnyIRlfEklviksLkqYtvtssvelqkqvleLLaqLvqlrvnyclldsdqvfigfvLkqfeyiEeGqvresedlipkiF 716 
                   +l++v+k +r+d+++i+n+IRlfE+lvik+LkqYt+t+ v+lqkqvl+LLaqLvqlrvnyclldsdqvfigfvLkqfeyiE+Gq+rese++ip+iF
  NP_002102.4 1406 NLTSVTK-NRADKNAIHNHIRLFEPLVIKALKQYTTTTCVQLQKQVLDLLAQLVQLRVNYCLLDSDQVFIGFVLKQFEYIEVGQFRESEAIIPNIF 1500
                   ***9999.9*************************************************************************************** PP

   Htt_N-HEAT  717 qFLvlLSyeryhskaiigipkiiqlcdglmasgqravthciPAlqPivediFlvRnslkaeeakeleaqrevvlakLlrLleyhevvellililds 812 
                   +FLvlLSyeryhsk+iigipkiiqlcdg+masg++avth+iPAlqPiv+d+F++R+++ka+++kele+q+evv+++LlrL++yh+v+e++il+l++
  NP_002102.4 1501 FFLVLLSYERYHSKQIIGIPKIIQLCDGIMASGRKAVTHAIPALQPIVHDLFVLRGTNKADAGKELETQKEVVVSMLLRLIQYHQVLEMFILVLQQ 1596
                   ************************************************************************************************ PP

   Htt_N-HEAT  813 crveaneekwkrasrqvadvvLpllaklkisldsthql 850 
                   c++e ne+kwkr+srq+ad++Lp+lak+++++ds+++l
  NP_002102.4 1597 CHKE-NEDKWKRLSRQIADIILPMLAKQQMHIDSHEAL 1633
                   ****.*******************************97 PP



Or compare NP_002102.4 to CDD or PaperBLAST