SwissProt::P51112 has 3148 amino acids
Query: Htt_N-HEAT [M=851]
Accession: PF12372.12
Description: Huntingtin, N-terminal HEAT
Scores for complete sequences (score includes all domains):
--- full sequence --- --- best 1 domain --- -#dom-
E-value score bias E-value score bias exp N Sequence Description
------- ------ ----- ------- ------ ----- ---- -- -------- -----------
7e-306 1003.1 4.4 7e-306 1003.1 4.4 1.7 2 SwissProt::P51112
Domain annotation for each sequence (and alignments):
>> SwissProt::P51112
# score bias c-Evalue i-Evalue hmmfrom hmm to alifrom ali to envfrom env to acc
--- ------ ----- --------- --------- ------- ------- ------- ------- ------- ------- ----
1 ? -3.3 0.1 0.12 0.12 65 98 .. 84 118 .. 53 230 .. 0.64
2 ! 1003.1 4.4 7e-306 7e-306 2 850 .. 715 1626 .. 714 1627 .. 0.94
Alignments for each domain:
== domain 1 score: -3.3 bits; conditional E-value: 0.12
Htt_N-HEAT 65 ssgtlrlaisavesClrn....LadSkeflqlLqllie 98
s ++r+ + Cl+ L+dS+ + L+l e
SwissProt::P51112 84 SESDVRM---VADECLNRiikaLMDSNLPRLQLELYKE 118
4455555...2334444444445555555555555444 PP
== domain 2 score: 1003.1 bits; conditional E-value: 7e-306
Htt_N-HEAT 2 anhsDpqlrgvvllllekfikavlsqqvllyerwlqslesiknrkaqdldalvklllkgLkdessgtlrlaisavesClrnLadSkeflq 91
+h Dpq+rg++++l+ i+a ls+ +++ +wl+s++s+++ + +l +lv ll+k+Lkdess+t+++a+sav++C+ +L+ S +++
SwissProt::P51112 715 IDHGDPQIRGATAILCAAIIQAALSKMRYNIHSWLASVQSKTG-NPLSLVDLVPLLQKALKDESSVTCKMACSAVRHCIMSLCGSTLSEL 803
68**************************************999.99******************************************** PP
Htt_N-HEAT 92 lLqlliellalktsaywlvkvellellaklkyvlve..............nitassrlqervldsvliallqdedprvrsaaaaaivkai 167
+L+l+ +l alk s+ywlv++elle+la+++++lv+ ++t+ rlqervl++v+i+ll+d+dprvr++aa+a+ +++
SwissProt::P51112 804 GLRLVVDLFALKDSSYWLVRTELLETLAEMDFRLVNflerksealhkgehHYTGRLRLQERVLNDVVIQLLGDDDPRVRHVAASAVSRLV 893
****************************************************************************************** PP
Htt_N-HEAT 168 pkLfyktrs.eedeitakAkelsekllscltellveleshdslisaaskayslLakrsnvcrtkdalesslSrivcklselLlvsaskal 256
++Lf+ +++ ++d ++a A+++s+ +l+ l++ ++ +++ ++s++ + y + +nv + ++e++lSr+v+++s+ + s+s+al
SwissProt::P51112 894 SRLFFDCDQgQADPVVAIARDQSSVYLQLLMHETQP--PSQLTVSTITRTYRGFNLSNNV--ADVTVENNLSRVVTAVSHAFTSSTSRAL 979
******************************955533..3667899999999999998898..89************************** PP
Htt_N-HEAT 257 llgCleallalsleypvalyekaWgckv.......ksklkrd.......................asvakdesaqqvelgllslvlsLLs 316
++gC+eal+ l ++p+++++++W+c + s+a d + ++g +++vlsLLs
SwissProt::P51112 980 TFGCCEALCLLAVHFPICTWTTGWHCGHissqssfS-----SrvgrsrgrtlsvsqsgstpasstTSSAVDPERRTLTVGTANMVLSLLS 1064
**************************8657666552.....034444777788889999999999999********************** PP
Htt_N-HEAT 317 ssylnfdltaHldlLilagnLlagaalrnik.........lsdsepsk...............Wdalsdtvlvrlaeqllrhvlrllnil 382
s+++++dl+aH+d+L+l+gnLla++a + ++ + W+alsd+ +v ++eql++h+l++lni+
SwissProt::P51112 1065 SAWFPLDLSAHQDALLLCGNLLAAVAPKCLRnpwageddsS------SsstntsggthkmeepWAALSDRAFVAMVEQLFSHLLKVLNIC 1148
*******************************9*85555442......244556689999******************************* PP
Htt_N-HEAT 383 aevlddvtpgqatkdalpslqalqvlSplkrlkeeekkekepserlarr..qssparngi.........vakkeslGsFlhvphylrlye 461
a+vldd +pg++ k+ lpsl+++++lSp++r +++ ++ + s +l+++ + a +g+ v+k+ +lGsF+h+p yl+ly+
SwissProt::P51112 1149 AHVLDDTPPGPPVKATLPSLTNTPSLSPIRRKGKDKDAVDSSSAPLSPKkgNE--ANTGRptestgstaVHKSTTLGSFYHLPPYLKLYD 1236
*******************************7777777777777777643322..222225558888889******************** PP
Htt_N-HEAT 462 iLkaaysnYkvtLaggeaedkfaslLlkdLevfsqllelAtlqedgkiaeevLmylkleiqsepkatvrcvqqLLksLFgtNlasnls.. 549
+Lka+++n+kv L+ +++kf s+L+++L+v+sqllelAtl+++ k++ee+L+ylk+++++ep++++ cvqqLLk+LFgtNlas+++
SwissProt::P51112 1237 VLKATHANFKVMLDLHSNQEKFGSFLRAALDVLSQLLELATLNDINKCVEEILGYLKSCFSREPTMATVCVQQLLKTLFGTNLASQYEgf 1326
***************************************************************************************9** PP
Htt_N-HEAT 550 ...pskqearllRealagslaamlsgfyhkifqhPlarvsealrvansss.skvqaeeeae...wlgllkkkslkvarklaavlkgvrnd 632
ps+++ ++lR ++sl ++g+yh++f++P++++++al a++s ++vqae+e++ w+++++k s + +++a+ r d
SwissProt::P51112 1327 lsgPSRSQGKALR-LGSSSL---RPGLYHYCFMAPYTHFTQAL--ADASLrNMVQAEHEQDtsgWFDVMQKTSNQLRSNIANAAR-HRGD 1409
*************.889999...9*******************..888888999*99999999*****************97766.9*** PP
Htt_N-HEAT 633 ektilnyIRlfEklviksLkqYtvtssvelqkqvleLLaqLvqlrvnyclldsdqvfigfvLkqfeyiEeGqvresedlipkiFqFLvlL 722
+++i+n+IRlfE+lvik+LkqYt+ +sv+lq+qvl+LLaqLvqlrvnyclldsdqvfigfvLkqfeyiE+Gq+r+se++ip+iF+FLvlL
SwissProt::P51112 1410 KNAIHNHIRLFEPLVIKALKQYTTSTSVALQRQVLDLLAQLVQLRVNYCLLDSDQVFIGFVLKQFEYIEVGQFRDSEAIIPNIFFFLVLL 1499
****************************************************************************************** PP
Htt_N-HEAT 723 SyeryhskaiigipkiiqlcdglmasgqravthciPAlqPivediFlvRnslkaeeakeleaqrevvlakLlrLleyhevvellililds 812
Syeryhsk+ii ipkiiqlcdg+masg++avth+iPAlqPiv+d+F++R+s+ka+++kele+q+evv+++LlrL++yh+v+e++il+l++
SwissProt::P51112 1500 SYERYHSKQIISIPKIIQLCDGIMASGRKAVTHAIPALQPIVHDLFVLRGSNKADAGKELETQKEVVVSMLLRLVQYHQVLEMFILVLQQ 1589
****************************************************************************************** PP
Htt_N-HEAT 813 crveaneekwkrasrqvadvvLpllaklkisldsthql 850
c++e ne+kwkr+srq+adv+Lp++ak++++lds ++l
SwissProt::P51112 1590 CHKE-NEDKWKRLSRQIADVILPMIAKQQMHLDSPEAL 1626
****.*****************************9987 PP
Or compare SwissProt::P51112 to CDD or PaperBLAST