Family Search for PF03649 (UPF0014)

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PF03649 hits 19 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.

YbbM / b0491 putative iron ABC exporter membrane subunit FetB from Escherichia coli K-12 substr. MG1655 (see 4 papers)
FETB_ECOLI / P77307 Probable iron export permease protein FetB from Escherichia coli (strain K12) (see paper)
Aligns to 8:245 / 259 (91.9%), covers 99.2% of PF03649, 273.9 bits

• function: Part of the ABC transporter complex FetAB, which is probably involved in iron export and enhances resistance to H(2)O(2)-mediated oxidative stress. Probably responsible for the translocation of the substrate across the membrane.
  subunit: The complex is composed of two ATP-binding proteins (FetA) and two transmembrane proteins (FetB).
  disruption phenotype: Mutant exhibits increased sensitivity to H(2)O(2) stress.

STAR2_ORYSJ / Q5W7C1 UPF0014 membrane protein STAR2; Protein SENSITIVE TO ALUMINUM RHIZOTOXICITY 2 from Oryza sativa subsp. japonica (Rice) (see 2 papers)
Aligns to 34:271 / 285 (83.5%), covers 98.3% of PF03649, 230.8 bits

• function: Associates with STAR2 to form a functional transmembrane ABC transporter required for detoxification of aluminum (Al) in roots. Can specifically transport UDP-glucose.
  subunit: Interacts with STAR2.
  disruption phenotype: No visible phenotype under normal growth condition, but strong inhibition of root elongation when grown in the presence of Al.

ALS3_ARATH / Q9ZUT3 Protein ALUMINUM SENSITIVE 3; ABC transporter I family member 16; ABC transporter ABCI.16; AtABCI16; ybbM homolog protein from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
Aligns to 22:259 / 273 (87.2%), covers 98.3% of PF03649, 225.4 bits

• function: Required for aluminum (Al) resistance/tolerance, probably by translocating Al from sensitive tissues such as growing roots to tissues less sensisitive to the toxic effects of Al.

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