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Family Search for PF04190 (GET4)

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Running HMMer for PF04190

PF04190 hits 13 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.

GET4_ASPFU / Q4WDK4 Golgi to ER traffic protein 4 from Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata) (see 2 papers)
Aligns to 38:314 / 346 (80.1%), covers 100.0% of PF04190, 293.9 bits

GET4_YEAST / Q12125 Golgi to ER traffic protein 4; Guided entry of tail-anchored proteins 4 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 4 papers)
TC 3.A.21.1.1 / Q12125 Golgi to ER traffic protein 4, component of The C-terminal Tail-anchored (TA) membrane protein biogenesis/ insertion complex, Get1/Get2/Get3 (Stefer et al., 2011; Kubota et al. 2012; Wang et al. 2014). The ATPase (Get3) is homologous to ArsA of the arsenite exporters (Castillo and Saier, 2010). Get1 and Get2 but not Get3 are required for mitochondrial autophagy, either because of a requirement for Get1/2-dependent TA protein(s), or because the Get1/2 complex itself acts specifically in mitophagy from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
NP_014807 Get4p from Saccharomyces cerevisiae S288C
YOR164C Protein of unknown function; interacts with Mdy2p from Saccharomyces cerevisiae
Aligns to 46:308 / 312 (84.3%), covers 100.0% of PF04190, 276.9 bits

F1LXF5 Guided entry of tail-anchored proteins factor 4 from Rattus norvegicus
Aligns to 59:309 / 330 (76.1%), covers 100.0% of PF04190, 263.4 bits

Q9D1H7 Golgi to ER traffic protein 4 homolog from Mus musculus
Aligns to 56:306 / 327 (76.8%), covers 100.0% of PF04190, 261.8 bits

GET4_HUMAN / Q7L5D6 Golgi to ER traffic protein 4 homolog; Conserved edge-expressed protein; Transmembrane domain recognition complex 35 kDa subunit; TRC35 from Homo sapiens (Human) (see 7 papers)
NP_057033 Golgi to ER traffic protein 4 homolog from Homo sapiens
Aligns to 56:306 / 327 (76.8%), covers 98.4% of PF04190, 260.5 bits

3lkuE / Q12125 Crystal structure of s. Cerevisiae get4 in complex with an n-terminal fragment of get5 (see paper)
Aligns to 38:291 / 291 (87.3%), covers 96.1% of PF04190, 259.2 bits

GET4_SCHPO / O74432 Golgi to ER traffic protein 4 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
Aligns to 33:290 / 303 (85.1%), covers 100.0% of PF04190, 247.8 bits

GET4_ARATH / Q6GKV1 Protein GET4; AtGET4; Guided entry of tail-anchored proteins 4 homolog from Arabidopsis thaliana (Mouse-ear cress) (see paper)
AT5G63220 hypothetical protein from Arabidopsis thaliana
Aligns to 46:320 / 324 (84.9%), covers 99.6% of PF04190, 242.1 bits

M1ACL9 Golgi to ER traffic protein 4 homolog from Solanum tuberosum
Aligns to 47:322 / 328 (84.1%), covers 99.6% of PF04190, 241.4 bits

B8ADF2 Golgi to ER traffic protein 4 homolog from Oryza sativa subsp. indica
Aligns to 55:328 / 330 (83.0%), covers 100.0% of PF04190, 233.7 bits

CNAG_00673 cytoplasmic protein from Cryptococcus neoformans var. grubii H99
Aligns to 43:334 / 338 (86.4%), covers 99.2% of PF04190, 187.4 bits

PF3D7_1438600 conserved protein, unknown function from Plasmodium falciparum 3D7
Aligns to 38:276 / 277 (86.3%), covers 99.6% of PF04190, 162.8 bits

C9JPA8 Guided entry of tail-anchored proteins factor 4 (Fragment) from Homo sapiens
Aligns to 3:148 / 148 (98.6%), covers 57.6% of PF04190, 143.0 bits

Or search for genetic data about PF04190 in the Fitness Browser

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory