Family Search for PF04759 (DUF617)
April 2024: See Interactive Tools for Functional Annotation of Bacterial Genomes for advice on using these tools.
PF04759 hits 8 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.
LOC100263245 protein MIZU-KUSSEI 1 from Vitis vinifera
Aligns to 65:222 / 223 (70.9%), covers 100.0% of PF04759, 235.9 bits
MIZ1_ARATH / O22227 Protein MIZU-KUSSEI 1 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
AT2G41660 MIZ1 (mizu-kussei 1) from Arabidopsis thaliana
NP_565953 MIZU-KUSSEI-like protein (Protein of unknown function, DUF617) from Arabidopsis thaliana
Aligns to 129:296 / 297 (56.6%), covers 100.0% of PF04759, 228.6 bits
- function: Plays a role in lateral root development by maintaining auxin levels. This function requires GNOM (GN/MIZ2) activity. Negatively regulates cytokinin sensitivity on root development. Positively regulates hydrotropism in roots.
disruption phenotype: No visible phenotype under normal growth conditions, but mutant plants are impaired in hydrotropic response. - The link between hydrotropism and phototropism in Arabidopsis roots
Yadav, Journal of experimental botany 2023 - “...al., 2007 ). The phenotypic changes result from a single recessive mutation in MIZ1 , At2g41660, which encodes a protein containing a domain (the MIZ domain) that is highly conserved among terrestrial plants such as rice and moss. Unfortunately, MIZ1 is a protein with an uncharacterized...”
- Unraveling the Diverse Roles of Neglected Genes Containing Domains of Unknown Function (DUFs): Progress and Perspective
Lv, International journal of molecular sciences 2023 - “...trichome development Arabidopsis [ 18 , 38 ] Other essential growth and development MIZ1 ( At2g41660 ) DUF617 PF04759 MIZ1 regulates lateral root development in Arabidopsis Arabidopsis [ 20 ] REL2 ( NP_001065395.1 ) DUF630; DUF632 PF04783; PF04782 Controls leaf rolling in rice Oryza sativa [...”
- Transcriptional network underpinning ploidy-related elevated leaf potassium in neo-tetraploids
Fischer, Plant physiology 2022 - “...MOT1 (AT2G25680), CASP3 (AT2G27370), FRU (AT2G28160), (AT2G28990), ZIP3 (AT2G32270), UCC1 (AT2G32300), (AT2G37820), (AT2G39430), (AT2G40240), MIZ1 (AT2G41660), (AT2G43590), VQ18 (AT2G44340), (AT2G45180), NF-YB5 (AT2G47810), (AT3G01345), (AT3G01572), RGF7 (AT3G02240), ABR (AT3G02480), HSFA1E (AT3G02990), (AT3G11150), (AT3G18450), (AT3G24020), NIMIN-2 (AT3G25882), NUDX13 (AT3G26690), (AT3G29647), QQS (AT3G30720), (AT3G46280), (AT3G51340), CYP76G1 (AT3G52970), (AT3G56730), (AT4G07820),...”
- Root electrotropism in Arabidopsis does not depend on auxin distribution but requires cytokinin biosynthesis
Salvalaio, Plant physiology 2022 - “...) under accession numbers: AUX1 , AT2G38120; PIN2 , AT5G57090; CYP735A1 , AT5G38450; MIZ1 , AT2G41660; ATIPT1 , AT1G68460; ATIPT3 , AT3G63110; ATIPT5 , AT5G19040; and ATIPT7 , AT3G23630. Supplemental data The following materials are available in the online version of this article. Supplemental Figure S1...”
- Root Plasticity in the Pursuit of Water
Fromm, Plants (Basel, Switzerland) 2019 - “...response first revealed an ahydrotropic mutant with a point mutation in a gene named MIZ1 (At2g41660) [ 68 ], until recently of unknown cellular or biochemical function. The mutation in MIZ1 that abolished hydrotropism substitutes a Glycine to Glutamic acid at position 235 [ 68 ]....”
- BR-INSENSITIVE1 regulates hydrotropic response by interacting with plasma membrane H+-ATPases in Arabidopsis
Yuan, Plant signaling & behavior 2018 - “...Arabidopsis, such as the Mizu-kussei1 (MIZ1; AT2G41660), Mizu-kussei2 (MIZ2/GNOM; AT1G13980), and altered hydrotropic response1 (ahr1), no hydrotropic response1...”
- A gene essential for hydrotropism in roots
Kobayashi, Proceedings of the National Academy of Sciences of the United States of America 2007 - “...in miz1, one in At2g41570 and the other in At2g41660. Mutant lines for At2g41570 and At2g41660 are shown with their T-DNA insertion sites: SALK113906 for...”
- “...in miz1 plants with an introduced At2g41570 or At2g41660 gene and hydrotropic response of the T-DNA insertion lines. (A) Complementation of miz1 by introduction...”
- Arabidopsis SHORT INTEGUMENTS 2 is a mitochondrial DAR GTPase
Hill, Genetics 2006 - “...comprises four complete predicted coding regions (At2g41660, 41670, 41680, and 41690; TAIR, http://www.arabidopsis. org/). Subclones spanning these coding...”
- Recovery of root hydrotropism in miz1 mutant by eliminating root gravitropism.
Li, Journal of plant physiology 2024 (PubMed)- GeneRIF: Recovery of root hydrotropism in miz1 mutant by eliminating root gravitropism.
- MIZU-KUSSEI1 (MIZ1) and GNOM/MIZ2 control not only positive hydrotropism but also phototropism in Arabidopsis roots.
Pang, Journal of experimental botany 2023 (PubMed)- GeneRIF: MIZU-KUSSEI1 (MIZ1) and GNOM/MIZ2 control not only positive hydrotropism but also phototropism in Arabidopsis roots.
- MIZ1 acts downstream of PGM1 in regulating root hydrotropism.
Liu, Biochemical and biophysical research communications 2023 (PubMed)- GeneRIF: MIZ1 acts downstream of PGM1 in regulating root hydrotropism.
- MIZ1 regulates ECA1 to generate a slow, long-distance phloem-transmitted Ca2+ signal essential for root water tracking in Arabidopsis.
Shkolnik, Proceedings of the National Academy of Sciences of the United States of America 2018 - GeneRIF: the inhibition of ECA1 by MIZ1 changes the balance between cytosolic Ca(2+) influx and efflux and generates the cytosolic Ca(2+) signal required for water tracking.
- MIZ1-regulated hydrotropism functions in the growth and survival of Arabidopsis thaliana under natural conditions.
Iwata, Annals of botany 2013 - GeneRIF: MIZ1-regulated hydrotropism functions in the growth and survival of Arabidopsis thaliana
- MIZ1, an essential protein for root hydrotropism, is associated with the cytoplasmic face of the endoplasmic reticulum membrane in Arabidopsis root cells.
Yamazaki, FEBS letters 2012 (PubMed)- GeneRIF: MIZ1-GFP was detected at high levels in cortical cells and lateral root cap cells and accumulated in compartments in cortical cells.
- Overexpression of MIZU-KUSSEI1 enhances the root hydrotropic response by retaining cell viability under hydrostimulated conditions in Arabidopsis thaliana.
Miyazawa, Plant & cell physiology 2012 (PubMed)- GeneRIF: Overexpression of MIZ1 enhances tolerance to osmotic stress.
- Hormonal regulation of lateral root development in Arabidopsis modulated by MIZ1 and requirement of GNOM activity for MIZ1 function.
Moriwaki, Plant physiology 2011 - GeneRIF: MIZ1 plays a role in lateral root development by maintaining auxin levels and its function requires GNOM activity.
- More
AT5G23100 hypothetical protein from Arabidopsis thaliana
Aligns to 90:276 / 277 (67.5%), covers 100.0% of PF04759, 225.9 bits
- Global gene regulatory network underlying miR165a in Arabidopsis shoot apical meristem
Sinha, Scientific reports 2023 - “...AT1G49475 AP2/B3-like transcriptional factor family protein AT1G68630 PLAC8 family protein AT4G24050 NAD(P)-binding Rossmann-fold superfamily protein AT5G23100 MIZU-KUSSEI-like protein AT3G02000 ROXY1 It is required for proper petal initiation and organogenesis AT5G43810 ZWILLE (ZLL)/ARGONAUTE 10 (AGO10) specifically sequesters miR166/165 AT1G13710 KLUH (KLU) Contributes to growth-stimulating signal AT5G43870 FORKED-LIKE1...”
AT5G42680 hypothetical protein from Arabidopsis thaliana
Aligns to 77:236 / 238 (67.2%), covers 99.4% of PF04759, 219.0 bits
- Differential transcriptome analysis reveals insight into monosymmetric corolla development of the crucifer Iberis amara
Busch, BMC plant biology 2014 - “..., (H) Rcd1-like and (I) a contig with homology to a protein of unknown function (At5g42680). aBp, abaxial petal; aDp, adaxial petal. From these data, a general picture emerges, where adaxial petals are characterized by a pool of transcripts enriched in genes involved in cell wall...”
- “...expression in adaxial petals of a gene that shows highest homology to the Arabidopsis gene At5G42680 encoding for a protein of unknown function (Figure 4 I), confirms the differential expression of a member of this highly abundant class of transcripts upregulated in adaxial petals. In summary,...”
AT1G21050 hypothetical protein from Arabidopsis thaliana
Aligns to 87:244 / 245 (64.5%), covers 100.0% of PF04759, 218.8 bits
GRMZM2G043117 plant-specific domain TIGR01570 family protein from Zea mays
Aligns to 117:292 / 293 (60.1%), covers 100.0% of PF04759, 218.0 bits
AT2G22460 hypothetical protein from Arabidopsis thaliana
Aligns to 85:242 / 245 (64.5%), covers 99.4% of PF04759, 201.6 bits
- The heat is on: a simple method to increase genome editing efficiency in plants
Blomme, BMC plant biology 2022 - “...vectors targeting PDS3 as well as seven additional Cas9 targets: GLABRA1 ( GL1-2; AT3G27920 ), AT2G22460 , IMMUTANS1 ( IM1; AT4G22260 ), VARIEGATED1-1 ( VAR1; AT5G42270 ) and VAR1-2 , TRANSPORT INHIBITOR RESPONSE 1-1 ( TIR1-1; AT3G62980 ) or AT4G12990 (Fig. 3 ). All transformants were...”
- “...results obtained in T2 lines (Figs. 1 and 3 ). For two targets, VAR1-1 and AT2G22460 , the average increase in indels was 27% upon 3xHS. For the four remaining targets, the effect of 3xHS was more pronounced: 44% for IM-1 , 55% for VAR1-2 ,...”
AT1G76610 hypothetical protein from Arabidopsis thaliana
Aligns to 76:225 / 226 (66.4%), covers 100.0% of PF04759, 198.2 bits
Or search for genetic data about PF04759 in the Fitness Browser
by Morgan Price,
Arkin group
Lawrence Berkeley National Laboratory