Family Search for PF08522 (DUF1735)
April 2024: See Interactive Tools for Functional Annotation of Bacterial Genomes for advice on using these tools.
PF08522 hits 23 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.
BT4040 putative galactose oxidase precursor from Bacteroides thetaiotaomicron VPI-5482
2 alignments in 25:277 / 447 (54.1%), covering up to 93.3% of PF08522, 120.5 bits
- Iron Deficiency Modulates Metabolic Landscape of Bacteroidetes Promoting Its Resilience during Inflammation
Lewis, Microbiology spectrum 2023 - “...as the Rag/Sus family nutrient uptake protein (BT4724 to BT4725, BT4294 to BT4299, BT4038 to BT4040, BT3958 to BT3959, BT3951 to BT3953, BT3854 to BT3858, BT3786 to BT3792, BT3344 to BT3347, BT3087 to BT3090, BT3045 to BT3047, BT3024 to BT3028, BT3012 to BT3016, BT2804 to BT2809,...”
- Sulfatases and a radical S-adenosyl-L-methionine (AdoMet) enzyme are key for mucosal foraging and fitness of the prominent human gut symbiont, Bacteroides thetaiotaomicron
Benjdia, The Journal of biological chemistry 2011 - “...glycosidases and a galactose oxidase (BT0683, BT0757, BT4040, and BT4295), and several hypothetical proteins from operons containing sulfatase genes (BT0749...”
- “...BT3987 BT3988 BT4034 BT4035 BT4036 BT4037 BT4038 BT4039 BT4040 BT4041 BT4042 BT4043 BT4293 BT4294 BT4295 BT4296 BT4297 BT4298 BT4299 BT4300 BT4627 BT4628 BT4629...”
- Integration and excision of a newly discovered bacteroides conjugative transposon, CTnBST
Wesslund, Journal of bacteriology 2007 - “...is between two genes encoding small hypothetical proteins (BT4040 and BT4041). An analysis of the sequences of several integration sites for CTnBST revealed...”
BT0865, BT_0865 putative chitobiase from Bacteroides thetaiotaomicron VPI-5482
2 alignments in 27:273 / 440 (53.4%), covering up to 85.8% of PF08522, 114.5 bits
- Improving microbial fitness in the mammalian gut by in vivo temporal functional metagenomics
Yaung, Molecular systems biology 2015 - “...). At Day 7 in aerobic LB, enriched genes included metabolic enzymes, such as chitobiase (BT_0865), which degrades chitin, and stress response proteins, such as glycine betaine/Lproline transport system permease (BT_1750), which is involved in the import of osmoprotectants glycine betaine or proline that mitigate effects...”
- Sulfatases and a radical S-adenosyl-L-methionine (AdoMet) enzyme are key for mucosal foraging and fitness of the prominent human gut symbiont, Bacteroides thetaiotaomicron
Benjdia, The Journal of biological chemistry 2011 - “...only three genes, including a putative chitobiase (BT0865) and a periplasmic -glucosidase precursor (BT1872), exhibited significantly increased expression in...”
- “...to modify sulfated oligosaccharides. In contrast, the PUL BT0865- 67 exhibits dramatically diminished expression in the anSME strain, suggesting that the sensor...”
BT1036 hypothetical protein from Bacteroides thetaiotaomicron VPI-5482
2 alignments in 33:301 / 449 (55.7%), covering up to 95.0% of PF08522, 106.7 bits
BT1037, BT_1037 conserved hypothetical protein from Bacteroides thetaiotaomicron VPI-5482
Aligns to 21:137 / 395 (29.6%), covers 97.5% of PF08522, 93.6 bits
BT3790 hypothetical protein from Bacteroides thetaiotaomicron VPI-5482
Aligns to 33:160 / 324 (39.5%), covers 96.7% of PF08522, 79.3 bits
3n91A / A7M003 Crystal structure of a structural genomics, unknown function (bacova_03430) from bacteroides ovatus at 2.40 a resolution
Aligns to 1:132 / 315 (41.9%), covers 97.5% of PF08522, 75.4 bits
- Ligand: calcium ion (3n91A)
BACOVA_03430 hypothetical protein from Bacteroides ovatus ATCC 8483
Aligns to 30:161 / 344 (38.4%), covers 97.5% of PF08522, 75.1 bits
- Glycan complexity dictates microbial resource allocation in the large intestine
Rogowski, Nature communications 2015 - “...cell surface, likely to maximize efficiency of initial glycan capture. PUL-XylL encodes two potential SGBPs, BACOVA_03430 and BACOVA_03431. BACOVA_03430 did not bind to any of the xylans or xylooligosaccharides evaluated and thus is unlikely to be a SGBP. BACOVA_03431, a surface located lipoprotein ( Fig. 2...”
- “...MFS=transporter of the major facilitator superfamily (pink). Grey=unknown function (note, there is a structure of BACOVA_03430, PDB accession code 3N91). SusC-like (yellow) and SusD-like (light tan) proteins are a defining feature of PULs and are responsible for import of complex glycans across the outer membrane 18...”
BT1045, BT_1045 hypothetical protein from Bacteroides thetaiotaomicron VPI-5482
Aligns to 31:148 / 396 (29.8%), covers 95.0% of PF08522, 71.7 bits
- Iron Deficiency Modulates Metabolic Landscape of Bacteroidetes Promoting Its Resilience during Inflammation
Lewis, Microbiology spectrum 2023 - “...component I family protein, BT0995 encoding a PAS domain-containing sensor histidine kinase, locus BT1042 to BT1045 encoding a SusD/RagB transporter system, BT1597 encoding a HAMP domain-containing histidine kinase (followed by a second component of the system and a gene coding for a cation efflux pump, BEX),...”
- “...helix-turn-helix domain-containing protein Bt 3.760234 BT_1043 10.62892 SusD/RagB family nutrient-binding outer membrane protein Bt 8.318422 BT_1045 10.67078 DUF1735 domain-containing protein Bt, Pg, Pi 3.099403 BT_1138 1.56722 hypothetical protein, site-specific integrase Bt 2.279712 BT_1597 3.318077 Tetratricopeptide repeat protein, HAMP domain-containing histidine kinase Bt 3.294873 BT_1895 35.68394 Hypothetical...”
- Preferential packing of acidic glycosidases and proteases into Bacteroides outer membrane vesicles
Elhenawy, mBio 2014 - “...Xylanase Yes Acidic BT_1761 Xylanase Yes Acidic BT_3985 Chitinase Yes Acidic BT_1038 Chitinase Yes Acidic BT_1045 Glucanases Yes Acidic BT_3861 Glucanases Yes Acidic BT_2239 Protease Yes Acidic BT_3577 Serine protease No Acidic BT_2272 Zinc peptidase No Acidic BT_3522 Glucanases Yes Acidic BT_3237 Zinc peptidase Yes Acidic...”
- Structure of a SusD homologue, BT1043, involved in mucin O-glycan utilization in a prominent human gut symbiont
Koropatkin, Biochemistry 2009 - “...reducing end N -acetylglucosamine-containing oligosaccharides from glycosylated mucin proteins ( 13 , 41 ). Likewise, BT1045 encodes a predicted concanavalin A-like lectin/glucanase, that are sometimes found as part of multienzyme mucinase complexes ( 42 ). Both BT1044 and BT1045 contained predicted secretion and lipidation signal sequences...”
BT2624 hypothetical protein from Bacteroides thetaiotaomicron VPI-5482
Aligns to 31:160 / 321 (40.5%), covers 99.2% of PF08522, 67.1 bits
BT4407 conserved hypothetical protein from Bacteroides thetaiotaomicron VPI-5482
Aligns to 30:145 / 391 (29.7%), covers 97.5% of PF08522, 67.0 bits
Ccan_17440 DUF1735 domain-containing protein from Capnocytophaga canimorsus Cc5
Aligns to 30:155 / 440 (28.6%), covers 90.0% of PF08522, 66.9 bits
- Glycan-foraging systems reveal the adaptation of Capnocytophaga canimorsus to the dog mouth
Renzi, mBio 2015 - “...modules ( 31 ) and one F5/8 type C ( 32 ) carbohydrate binding module. Ccan_17440 is the most abundant PUL -encoded protein of the C.canimorsus 5 surfome ( 15 ) and also harbors an F5/8 type C carbohydrate binding module. Ccan_17430 (mucinase) and Ccan_17450 (SusD-like)...”
- “...the eluate identified 35 proteins (see TableS1 in the supplemental material), among which were Ccan_17450, Ccan_17440, and Ccan_17430 . Thirteen proteins were identified in the mock eluate, of which 11 were also present in the Ccan_17470Strep-His eluate. No PUL9 -encoded product was identified in the mock...”
BT3986 putative patatin-like protein from Bacteroides thetaiotaomicron VPI-5482
Aligns to 32:150 / 384 (31.0%), covers 99.2% of PF08522, 66.8 bits
- Structural basis of mammalian high-mannose N-glycan processing by human gut Bacteroides
Trastoy, Nature communications 2020 - “...the released HM is held on the surface of B. thetaiotaomicron through the mannose-binding protein BT3986, while BT3984 recognizes the GlcNAc at the reducing end of the glycan and orientates the glycan into the outer membrane porin BT3983) for transport into the periplasm (Fig. 1 )...”
- “...in the cell surface. The HM product interacts with the surface glycan binding protein (SGBP), BT3986, and the SusD homolog BT3984 interacts with the reducing end GlcNAc, orientating the glycan into the SusC homolog BT3983 porin. The HM glycan is transported to the periplasm where it...”
- Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism
Cuskin, Nature 2015 - “.... The released HMNG is held on the surface of Bt through the mannose-binding protein BT3986, while the SusD homolog, BT3984, by recognizing the reducing end GlcNAc, Extended Data Fig. 7ef and Supplementary Table 5 , likely orientates the glycan into the outer membrane porin (SusC...”
- “...isothermal calorimetry titrations (ITCs) for BT3984 titrated with Gal-1,4-GlcNAc (LacNAc; (25 mM), and f, for BT3986 titrated with mannose (50 mM). The top half of each panel shows the raw ITC heats; the bottom half, the integrated peak areas fitted using a one single binding model...”
BT_RS18570 DUF4361 domain-containing protein from Bacteroides thetaiotaomicron VPI-5482
BT3682 hypothetical protein from Bacteroides thetaiotaomicron VPI-5482
Aligns to 31:154 / 295 (42.0%), covers 99.2% of PF08522, 66.5 bits
- Iron Deficiency Modulates Metabolic Landscape of Bacteroidetes Promoting Its Resilience during Inflammation
Lewis, Microbiology spectrum 2023 - “...protein, PepSY-associated TM helix domain-containing protein, hypothetical protein, DUF4876 domain-containing proteins, TonB-dependent receptor 5.2 0.084 BT_RS18570 BT3682 DUF4361 domain-containing protein 16.5 0.076 BT_RS18690 BT3707 Transposase 3.6 0.437 BT_RS1918590 BT3805 Response regulator, hypothetical protein 16.5 0.076 BT_RS19290 BT3826 Transposase 2.35.0 4E-070.006 BT_RS2002040 BT396872 Efflux RND transporter periplasmic...”
- Iron Deficiency Modulates Metabolic Landscape of Bacteroidetes Promoting Its Resilience during Inflammation
Lewis, Microbiology spectrum 2023 - “...PepSY-associated TM helix domain-containing protein, hypothetical protein, DUF4876 domain-containing proteins, TonB-dependent receptor 5.2 0.084 BT_RS18570 BT3682 DUF4361 domain-containing protein 16.5 0.076 BT_RS18690 BT3707 Transposase 3.6 0.437 BT_RS1918590 BT3805 Response regulator, hypothetical protein 16.5 0.076 BT_RS19290 BT3826 Transposase 2.35.0 4E-070.006 BT_RS2002040 BT396872 Efflux RND transporter periplasmic adaptor...”
Q8A0N4 endo-β-N-acetylglucosaminidase from Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50) (see paper)
AAO79092.1 endo-β-N-acetylglucosaminidase (BT3987;BT_3987) (EC 3.2.1.96) (see protein)
BT3987, BT_3987 endo-beta-N-acetylglucosaminidase F1 precursor from Bacteroides thetaiotaomicron VPI-5482
Q8A0N4 Endo-beta-N-acetylglucosaminidase F1 from Bacteroides thetaiotaomicron (strain ATCC 29148 / DSM 2079 / JCM 5827 / CCUG 10774 / NCTC 10582 / VPI-5482 / E50)
Aligns to 44:163 / 476 (25.2%), covers 99.2% of PF08522, 66.1 bits
- N-glycan breakdown by bacterial CAZymes
Crouch, Essays in biochemistry 2023 - “...[ 24 ]. In contrast, the archetypal human gut microbe Bacteroides thetaiotaomicron has a GH18 (BT3987) that can remove full high-mannose N-glycans, which are then imported into the cell for further degradation [ 12 ]. This species is also capable of utilising complex N-glycans, but there...”
- “...Examples of these include the broad-acting EndoS2 predominantly recognising the 1,3 arm and the high-mannose/hybrid-specific BT3987 as predominantly recognising the 1,6 arm of the glycan ( Figure 5 ). As this impacts on the way high-mannose N-glycans are recognised, the glycans adopt different conformations when bound...”
- GH18 endo-β-N-acetylglucosaminidases use distinct mechanisms to process hybrid-type N-linked glycans
Trastoy, The Journal of biological chemistry 2021 - “...EndoS2 and EndoBT-3984 with GH18 family enzymes with known HM-type N -glycan specificity. Comparison of BT3987 from B.thetaiotaomicron VPI-5482 (Q8A0N4, Uniprot code), EndoF1 from Elizabethkingia meningoseptica (P36911, Uniprot code), BT1285 from B.thetaiotaomicron VPI-5482 (Q8A889, Uniprot code), EndoH from Streptomyces plicatus (P04067, Uniprot code), EF2863 from Enterococcus...”
- Structural basis of mammalian high-mannose N-glycan processing by human gut Bacteroides
Trastoy, Nature communications 2020 - “...these species 7 . Fig. 1 Depolymerization of HM-type N -glycans by B. thetaiotaomicron . BT3987 deglycosylates HM-glycoproteins in the cell surface. The HM product interacts with the surface glycan binding protein (SGBP), BT3986, and the SusD homolog BT3984 interacts with the reducing end GlcNAc, orientating...”
- “...periplasm where it is processed by three mannosidases to the trisaccharide Man--1,6-Man-1,4-GlcNAc. Cartoon representation of BT3987 (PDB CODE 6T8I) and BT3990 (PDB CODE 2WVZ), and surface representation of BT3984 (PDB CODE 3CGH; 7). EndoBT-3987 is an endo-- N -acetylglucosaminidase (ENGase) that specifically catalyzes the hydrolysis of...”
- Structural basis for the specific cleavage of core-fucosylated N-glycans by endo-β-N-acetylglucosaminidase from the fungus Cordyceps militaris
Seki, The Journal of biological chemistry 2019 (secret) - Structural basis for the recognition of complex-type N-glycans by Endoglycosidase S
Trastoy, Nature communications 2018 - “...docking was performed using AutoDock Vina employing standard parameters 60 . Purification of EndoBT EndoBT (BT_3987 ( B. thetaiotaomicron VPI-5482)) in pSpeedET vector was purchased from DNASU plasmid repository ( https://dnasu.org/DNASU/Home.do ). EndoBT was expressed in BL21(DE3) (Novagen) in LB medium supplemented with 50lml 1 ampicillin....”
- Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism
Cuskin, Nature 2015 - “...requires GlcNAc at the reducing end for activity, producing Man-1,6-Man-1,4-GlcNAc, Extended Data Fig. 7b . BT3987 is a surface endo -acting N-acetylglucosaminidase, which cleaves the oligosaccharide from its polypeptide, Extended Data Fig. 7cd . The released HMNG is held on the surface of Bt through the...”
- “...in harness with HPAEC and fluorescence detection was used to measure the endo--N-acetylglucosaminidase activity of BT3987 against Man 9 GlcNAc 2 . The activity of the enzyme was also evaluated against glycoproteins using mass spectrometry using MALDI-TOF mass spectrometry as described below. BT2630 and BT3783 were...”
- Preferential packing of acidic glycosidases and proteases into Bacteroides outer membrane vesicles
Elhenawy, mBio 2014 - “...Acidic BT_3960 Cysteine proteinases Yes Acidic BT_1760 Levan hydrolase Yes Acidic BT_1737 -Amylase Yes Alkaline BT_3987 Endo-- N -acetylglucosaminidase Yes Acidic BT_3523 Glucanases Yes Acidic BT_3381 -Xylosidase Yes Acidic BT_1037 -Sialidase Yes Acidic BT_3745 Xylanase Yes Acidic BT_1761 Xylanase Yes Acidic BT_3985 Chitinase Yes Acidic BT_1038...”
- Structure of a SusD homologue, BT1043, involved in mucin O-glycan utilization in a prominent human gut symbiont
Koropatkin, Biochemistry 2009 - “...the SusC homolog, BT1042. Similarly, the BT3983-88 PUL, also encodes a predicted endo-- N -acetylglucosaminidase (BT3987). The mode of LacNAc binding to BT1043 is quite different from that observed by other LacNAc and/or O -glycan binding carbohydrate binding modules (CBMs). The crystal structures of the family...”
- GH18 endo-β-N-acetylglucosaminidases use distinct mechanisms to process hybrid-type N-linked glycans
Trastoy, The Journal of biological chemistry 2021 - “...GH18 family enzymes with known HM-type N -glycan specificity. Comparison of BT3987 from B.thetaiotaomicron VPI-5482 (Q8A0N4, Uniprot code), EndoF1 from Elizabethkingia meningoseptica (P36911, Uniprot code), BT1285 from B.thetaiotaomicron VPI-5482 (Q8A889, Uniprot code), EndoH from Streptomyces plicatus (P04067, Uniprot code), EF2863 from Enterococcus faecalis (Q830C5, Uniprot code),...”
- Structural basis of mammalian high-mannose N-glycan processing by human gut Bacteroides
Trastoy, Nature communications 2020 - “...N -glycans and inactive against CT-type N -glycans. Comparison of BT3987 from B. thetaiotaomicron VPI-5482 (Q8A0N4, Uniprot code), EndoH from Streptomyces plicatus (P04067, Uniprot code), EndoF1 from Elizabethkingia meningoseptica (P36911, Uniprot code), A6286 from Prevotella melaninogenica (D9RSV7, Uniprot code), BT1285 from B. thetaiotaomicron VPI-5482 (Q8A889, Uniprot...”
- High resolution crystal structure of the endo-N-Acetyl-β-D-glucosaminidase responsible for the deglycosylation of Hypocrea jecorina cellulases
Stals, PloS one 2012 - “...Uniprot access code P36911.1), and Bacteroides thetaiotaomicron Endo BT (PDB ID 3POH, Uniprot access code Q8A0N4). The glycosylated Asn in the sequons of H. jecorina EndoT are shaded grey. Yellow shaded amino acids are the C-terminal residues observed in the respective crystal structures. The Endo T...”
7nwfA / Q8A0N4 Crystal structure of bacteroides thetaiotamicron endobt-3987 in complex with hybrid-type glycan (galglcnacman5glcnac) product (see paper)
Aligns to 1:119 / 432 (27.5%), covers 97.5% of PF08522, 65.2 bits
- Ligands: beta-d-mannopyranose; alpha-d-mannopyranose (7nwfA)
BT2395 hypothetical protein from Bacteroides thetaiotaomicron VPI-5482
Aligns to 30:157 / 298 (43.0%), covers 99.2% of PF08522, 63.2 bits
- Iron Deficiency Modulates Metabolic Landscape of Bacteroidetes Promoting Its Resilience during Inflammation
Lewis, Microbiology spectrum 2023 - “...BT3047, BT3024 to BT3028, BT3012 to BT3016, BT2804 to BT2809, BT2614 to BT2632, BT2392 to BT2395, BT1280 to BT1285, BT1046 to BT1047, BT0438 to BT0440, BT0360 to BT0365, and BT0317 to BT0318) were downregulated ( Table6 ). Finally, conjugative transposon coding genes traN , traM ,...”
BT3485 hypothetical protein from Bacteroides thetaiotaomicron VPI-5482
BT_RS17625 DUF4973 domain-containing protein from Bacteroides thetaiotaomicron VPI-5482
Aligns to 28:155 / 345 (37.1%), covers 93.3% of PF08522, 62.0 bits
BT3344 hypothetical protein from Bacteroides thetaiotaomicron VPI-5482
BT_RS16930 DUF4973 domain-containing protein from Bacteroides thetaiotaomicron VPI-5482
Aligns to 26:157 / 336 (39.3%), covers 89.2% of PF08522, 61.5 bits
- Iron Deficiency Modulates Metabolic Landscape of Bacteroidetes Promoting Its Resilience during Inflammation
Lewis, Microbiology spectrum 2023 - “...0.005 BT_RS16855 BT3329 DUF4988 domain-containing protein 11.1 to 5.3 0 to 4E-07 BT_RS16930 to 45 BT3344 to 47 DUF4973 domain-containing protein, RagB/SusD family nutrient uptake outer memb. protein, TonB-dependent receptor, IPT/TIG domain-containing protein 19.4 0.044 BT_RS17260 to 265 BT3410 Heavy metal-binding domain-containing protein, hypothetical protein 3.1...”
- “...BT4038 to BT4040, BT3958 to BT3959, BT3951 to BT3953, BT3854 to BT3858, BT3786 to BT3792, BT3344 to BT3347, BT3087 to BT3090, BT3045 to BT3047, BT3024 to BT3028, BT3012 to BT3016, BT2804 to BT2809, BT2614 to BT2632, BT2392 to BT2395, BT1280 to BT1285, BT1046 to BT1047, BT0438...”
- A Ribose-Scavenging System Confers Colonization Fitness on the Human Gut Symbiont Bacteroides thetaiotaomicron in a Diet-Specific Manner
Glowacki, Cell host & microbe 2020 - “...PULs of unknown specificity (BT3024 3027 and BT3344 3347 ) were repressed. Further, several genes encoding tricarboxylic acid (TCA) cycle enzymes...”
- Iron Deficiency Modulates Metabolic Landscape of Bacteroidetes Promoting Its Resilience during Inflammation
Lewis, Microbiology spectrum 2023 - “...family protein 2.9 0.005 BT_RS16855 BT3329 DUF4988 domain-containing protein 11.1 to 5.3 0 to 4E-07 BT_RS16930 to 45 BT3344 to 47 DUF4973 domain-containing protein, RagB/SusD family nutrient uptake outer memb. protein, TonB-dependent receptor, IPT/TIG domain-containing protein 19.4 0.044 BT_RS17260 to 265 BT3410 Heavy metal-binding domain-containing protein,...”
BACCAC_03237 DUF1735 domain-containing protein from Bacteroides caccae ATCC 43185
Aligns to 51:183 / 512 (26.0%), covers 82.5% of PF08522, 49.3 bits
Ccan_08730 DUF1735 and LamG domain-containing protein from Capnocytophaga canimorsus Cc5
Aligns to 31:169 / 441 (31.5%), covers 95.8% of PF08522, 49.2 bits
- The N-glycan glycoprotein deglycosylation complex (Gpd) from Capnocytophaga canimorsus deglycosylates human IgG
Renzi, PLoS pathogens 2011 - “...by ermF ; Em r [13] Cc5PUL5 Replacement of Ccan_08700 , Ccan_08710 , Ccan_08720 , Ccan_08730 by ermF : Em r Manfredi et al. , submitted Cc5gpdC Replacement of Ccan_08700 by ermF using primers 5073, 5074, 5075, 5083; Em r This study Cc5 gpdD Replacement of...”
- “...by ermF using primers 5001, 5002, 5005, 5006; Em r This study Cc5gpdE Replacement of Ccan_08730 by ermF using primers 5951, 5952, 5953, 5954; Em r This study Cc5gpdF Replacement of Ccan_08740 by ermF using primers 5955, 5956, 5957, 5958; Em r This study Growth of...”
4jx0A / Q5L9W9 Crystal structure of a two domain protein with unknown function (bf3416) from bacteroides fragilis nctc 9343 at 2.90 a resolution
Aligns to 16:137 / 302 (40.4%), covers 80.0% of PF08522, 42.1 bits
- Ligand: magnesium ion (4jx0A)
BACCELL_00844 hypothetical protein from Bacteroides cellulosilyticus DSM 14838
Aligns to 56:185 / 490 (26.5%), covers 79.2% of PF08522, 39.2 bits
6tcvB / Q8A0N4 Crystal structure of bacteroides thetaiotamicron endobt-3987 in complex with man9glcnac2asn substrate (see paper)
Aligns to 4:93 / 397 (22.7%), covers 59.2% of PF08522, 33.3 bits
- Ligands: beta-d-mannopyranose; alpha-d-mannopyranose (6tcvB)
Or search for genetic data about PF08522 in the Fitness Browser
by Morgan Price,
Arkin group
Lawrence Berkeley National Laboratory