Family Search for PF08551 (DUF1751)

April 2024: See Interactive Tools for Functional Annotation of Bacterial Genomes for advice on using these tools.

PF08551 hits 21 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.

TM115_YEAST / Q12239 Transmembrane protein 115 homolog from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
Aligns to 72:170 / 342 (28.9%), covers 100.0% of PF08551, 110.7 bits

• function: May play a role in retrograde transport of proteins from the Golgi to the endoplasmic reticulum.
  subunit: Homooligomer.

TM115_HUMAN / Q12893 Transmembrane protein 115; Placental protein 6; Protein PL6 from Homo sapiens (Human) (see 3 papers)
Aligns to 49:151 / 351 (29.3%), covers 100.0% of PF08551, 99.8 bits

• function: May play a role in retrograde transport of proteins from the Golgi to the endoplasmic reticulum. May indirectly play a role in protein glycosylation in the Golgi.
  subunit: Homooligomer (PubMed:24806965). Interacts with COPB1 (PubMed:24806965). May interact with LMAN1 (PubMed:24806965). Interacts with the COG complex; probably through COG3 (PubMed:24806965).

D4GT94 rhomboid protease (EC 3.4.21.105) from Haloferax volcanii (see paper)
Aligns to 117:214 / 296 (33.1%), covers 88.9% of PF08551, 25.2 bits

Or search for genetic data about PF08551 in the Fitness Browser