Family Search for PF10224 (DUF2205)

April 2024: See Interactive Tools for Functional Annotation of Bacterial Genomes for advice on using these tools.

PF10224 hits 10 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.

SCOC_HUMAN / Q9UIL1 Short coiled-coil protein from Homo sapiens (Human) (see 3 papers)
Aligns to 79:154 / 159 (47.8%), covers 86.7% of PF10224, 92.4 bits

• function: Positive regulator of amino acid starvation-induced autophagy.
  subunit: Homodimer (PubMed:24098481). Interacts with ARL1, ARL2 and ARL3 (PubMed:11303027). Directly interacts with FEZ1 and UVRAG (PubMed:22354037, PubMed:24098481). The interaction with UVRAG is reduced by amino acid starvation, but the complex is stabilized in the presence of FEZ1. Interacts with NRBF2 (PubMed:22354037).

SLO1_YEAST / Q3E784 SCOCO-like protein 1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
Aligns to 12:85 / 85 (87.1%), covers 77.3% of PF10224, 35.8 bits

• subunit: Interacts with ARL3.

Or search for genetic data about PF10224 in the Fitness Browser