Family Search for PF10290 (YJL171C_Tos1_N)
April 2024: See Interactive Tools for Functional Annotation of Bacterial Genomes for advice on using these tools.
PF10290 hits 15 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.
TOS1_CANAL / A0A1D8PJA8 Probable circularly permuted 1,3-beta-glucanase TOS1; Secreted protein TOS1; EC 3.2.1.39 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see 6 papers)
Aligns to 36:98 / 467 (13.5%), covers 98.4% of PF10290, 99.3 bits
- function: Probable circularly permuted 1,3-beta-glucanase involved in cell wall modification through beta-1,3-glucan network alterations such as increased branching or remodeling (By similarity). Plays a role in engulfment by host macrophages (PubMed:26087349).
catalytic activity: Hydrolysis of (1->3)-beta-D-glucosidic linkages in (1->3)- beta-D-glucans.
disruption phenotype: Leads to a slight sensitivity to the cell wall damaging agent calcofluor white but not Congo red (PubMed:26087349). Increases the phagocytosis rate by host macrophages (PubMed:26087349).
TOS1_YEAST / P38288 Probable circularly permuted 1,3-beta-glucanase TOS1; Target of SBF protein 1; EC 3.2.1.39 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 4 papers)
Aligns to 38:100 / 455 (13.8%), covers 100.0% of PF10290, 96.6 bits
- function: Probable circularly permuted 1,3-beta-glucanase involved in cell wall modification through beta-1,3-glucan network alterations such as increased branching or remodeling.
catalytic activity: Hydrolysis of (1->3)-beta-D-glucosidic linkages in (1->3)- beta-D-glucans.
disruption phenotype: Leads to a slight sensitivity to the cell wall damaging agent calcofluor white (PubMed:15781460). Shows also a slightly decreased ability to grow at 39 degrees Celsius (PubMed:15781460). Results in an increased resistance to Quantazyme, a recombinant beta-1,3-glucanase that hydrolyzes beta-1,3-glucan (PubMed:15781460).
PGA52_CANAL / Q59L72 Probable circularly permuted 1,3-beta-glucanase PGA52; EC 3.2.1.39 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see 3 papers)
Aligns to 23:90 / 384 (17.7%), covers 96.8% of PF10290, 86.6 bits
- function: Probable circularly permuted 1,3-beta-glucanase involved in cell wall modification through beta-1,3-glucan network alterations such as increased branching or remodeling.
catalytic activity: Hydrolysis of (1->3)-beta-D-glucosidic linkages in (1->3)- beta-D-glucans.
TOH1_YEAST / P46992 Probable circularly permuted 1,3-beta-glucanase YJL171C; TOS1 homolog; EC 3.2.1.39 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 7 papers)
Aligns to 26:93 / 396 (17.2%), covers 98.4% of PF10290, 84.7 bits
- function: Probable circularly permuted 1,3-beta-glucanase involved in cell wall modification through beta-1,3-glucan network alterations such as increased branching or remodeling.
catalytic activity: Hydrolysis of (1->3)-beta-D-glucosidic linkages in (1->3)- beta-D-glucans.
PGA52_ARTBC / D4AQ83 Probable circularly permuted 1,3-beta-glucanase; Allergen Asp f 4 homolog; PGA52-like secreted protein ARB_06390; EC 3.2.1.39 from Arthroderma benhamiae (strain ATCC MYA-4681 / CBS 112371) (Trichophyton mentagrophytes) (see paper)
Aligns to 37:97 / 440 (13.9%), covers 96.8% of PF10290, 72.1 bits
- function: Probable circularly permuted 1,3-beta-glucanase involved in cell wall modification through beta-1,3-glucan network alterations such as increased branching or remodeling.
catalytic activity: Hydrolysis of (1->3)-beta-D-glucosidic linkages in (1->3)- beta-D-glucans.
Or search for genetic data about PF10290 in the Fitness Browser
by Morgan Price,
Arkin group
Lawrence Berkeley National Laboratory