Family Search for PF10356 (RRG7)

April 2024: See Interactive Tools for Functional Annotation of Bacterial Genomes for advice on using these tools.

PF10356 hits 2 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.

RRG7_YEAST / Q08774 Required for respiratory growth protein 7, mitochondrial from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 4 papers)
NP_014950 Rrg7p from Saccharomyces cerevisiae S288C
YOR305W Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO); YOR305W is not an essential gene from Saccharomyces cerevisiae
Aligns to 29:219 / 242 (78.9%), covers 100.0% of PF10356, 243.8 bits

• disruption phenotype: Impaired respiratory growth and sensitivity to 4- (N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO).
• Single-gene deletions that restore mating competence to diploid yeast.
  Schmidlin, FEMS yeast research 2008 (PubMed)
  • GeneRIF: deletion strains, ylr193cDelta/ylr193cDelta, yor305wDelta/yor305wDelta, and ypr170cDelta/ypr170cDelta, mate at very low frequencies with haploids of either or both MATa/MATalpha mating types.
• Systematic analysis of nuclear gene function in respiratory growth and expression of the mitochondrial genome in S. cerevisiae
  Stenger, Microbial cell (Graz, Austria) 2020
  • “...Proteins of unknown function IRC19 YLL033W RRG9 YNL213C YNL184C YNL184C RRG1 YDR065W SOV1 YMR066W RRG7 YOR305W YDR114C YDR114C Dubious ORFs YBL100C YBL100C YGR219W YGR219W YNL170W YNL170W YCL007C YCL007C YJL120W YJL120W YOR200W YOR200W YDL068W YDL068W YJR114W YJR114W YOR331C YOR331C YDR230W YDR230W YKL169C YKL169C YPR099C YPR099C YGL218W YGL218W...”
• Dynamic identifying protein functional modules based on adaptive density modularity in protein-protein interaction networks
  Shen, BMC bioinformatics 2015
  • “...yir009w yjl188c ykl012w ykl095w ykr019c ylr147c ylr275w ylr298c ylr318w yml046w ymr001c ymr132c ymr157c yor036w yor159c yor305w yor359w ypl213w ypr057w ypr182w 1.31e-21 22 out of 35 genes, 62.9% mRNA metabolic process ybl026w ybl098w ybr055c ycr077c ydl085c-a ydl121c ydl160c ydr055w ydr378c ydr473c yel015w yer112w yer146w yer172c ygl068w ygl173c...”
• Global genetic determinants of mitochondrial DNA copy number
  Zhang, PloS one 2014
  • “...YGR102C Mitochondrial, biological process unknown YGR150C Mitochondrial, biological process unknown YPR116W Mitochondrial, biological process unknown YOR305W Mitochondrial, biological process unknown YLR091W Mitochondrial hypothetical protein, biological process unknown QRI5 Mitochondrial protein of unknown function YOR199W Biological process unknown YOR205C Hypothetical protein, Biological process unknown QRI7 LOC64172 Mitochondrial,...”
• Chemogenomic and transcriptome analysis identifies mode of action of the chemosensitizing agent CTBT (7-chlorotetrazolo[5,1-c]benzo[1,2,4]triazine)
  Batova, BMC genomics 2010
  • “...REF2, RGI1, RNR4, RPL1B, RPL2A, RPL42B, RTC1, SBH1, YIM2 Unknown functions YDR049W, YDR114C, YHR045W, YNR065C, YOR305W Table 2 GO-terms significantly enriched in the 169 genes required for CTBT tolerance (SGD GO-termFinder). GO_term Frequency P-value response to stimulus 27.2% 2.28E-06 transcription 23.1% 2.73E-06 response to stress 20.1%...”
• Genome-wide deletion mutant analysis reveals genes required for respiratory growth, mitochondrial genome maintenance and mitochondrial protein synthesis in Saccharomyces cerevisiae
  Merz, Genome biology 2009
  • “...pet genes ( YDR065w , YGR150c , YJL046w , YLL033w , YLR091w , YMR293c , YOR305w , and YPR116w ) encode previously uncharacterized proteins, and earlier studies have revealed a respiratory-deficient phenotype for two additional ORFs of unknown function that were not covered by all three...”
  • “...RRG6 (HER2) YMR293c [ 6 , 34 , 35 ] - - Altered Absent RRG7 YOR305w [ 35 ] + + ND ND RRG8 YPR116w [ 35 ] - - Altered Absent RRG9 YNL213c [ 34 ] - - Altered WT RRG10 YJL062w-a [ 34 ,...”
• Genomewide screen for negative regulators of sirtuin activity in Saccharomyces cerevisiae reveals 40 loci and links to metabolism
  Raisner, Genetics 2008
  • “...sic1 kem1 pog1 ssd1 ygl081w yop1 rad10 rad54 YOR305w YMR007w ecm33 vrp1 YMR206W YLR079W YGL173C YIL122W YDR293C YGL081W YPR028W YML095C YGL163C YOR305W YMR007W...”
  • “...the genes RAD54, VRP1, ECM33 YOR206W, YMR007W, and YOR305W (Figure 3, F and G) displayed phenotypes that were unaffected by deletion of SIR3, suggesting...”
• Retroviruses and yeast retrotransposons use overlapping sets of host genes
  Irwin, Genome research 2005
  • “...(deletion mutants representing GAL7, GAL10, GAL3, YLR202C, IRA2, YOR305W, GAL4, RIP1, CBP2, YHR116W, MRPS16, COX10, GAL4, and PET494) (Giaever et al. 2002)....”
• Eucaryotic genome evolution through the spontaneous duplication of large chromosomal segments
  Koszul, The EMBO journal 2004
  • “...YOR290c YOR290c YOR290c YOR290c YOR290c YOR267c YOR272w YOR305w YOR307c YOR307c YOR316c YOR362c YOR370c YOR344c YOR372c YOR372c YOR372c YOR372c YOR380w YOR357c...”
  • “...YPR044c Subtelomeric V YCR027c YOR143c YOR267c YOR290c YOR305w YOR273w YOR290c Type indicates intra- and interchromosomal events. For details on classes I-III,...”

YIQ3_SCHPO / Q9UT40 Uncharacterized protein C824.03c, mitochondrial from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
SPAC824.03c conserved fungal protein from Schizosaccharomyces pombe
2 alignments in 50:193 / 247 (58.3%), covering up to 57.3% of PF10356, 137.0 bits

• Improved strains and plasmid vectors for conditional overexpression of His-tagged proteins in Haloferax volcanii
  Allers, Applied and environmental microbiology 2010
  • “...neighbor-joining tree was built using Schizosaccharomyces pombe SPAC824.03c as an outgroup. Nucleotide sequence accession numbers. The sequences of the major...”
  • “...selected archaea and bacteria and Schizosaccharomyces pombe SPAC824.03c (9). Conserved residues are indicated by gray shading, and identical residues are...”

Or search for genetic data about PF10356 in the Fitness Browser