Family Search for PF10595 (FAM161A_B)
April 2024: See Interactive Tools for Functional Annotation of Bacterial Genomes for advice on using these tools.
PF10595 hits 12 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.
F161B_HUMAN / Q96MY7 Protein FAM161B from Homo sapiens (Human) (see paper)
Aligns to 167:536 / 647 (57.2%), covers 99.7% of PF10595, 327.1 bits
- subunit: Interacts with FAM161A.
F161A_HUMAN / Q3B820 Protein FAM161A from Homo sapiens (Human) (see 8 papers)
Aligns to 234:592 / 660 (54.4%), covers 93.7% of PF10595, 162.8 bits
- function: Involved in ciliogenesis.
subunit: Interacts (via central region) with CFAP418 (via N-terminus); the interaction is direct (PubMed:36233334). Interacts (via C-terminus) with microtubules (PubMed:22791751). Interacts with LCA5 (PubMed:22940612). Interacts with CEP290 (PubMed:22940612). Interacts with SDCCAG8 (PubMed:22940612). Interacts with FAM161B (PubMed:22791751). Interacts with POC1B (PubMed:25018096). Interacts with CEP78 (PubMed:27588451).
F161A_MOUSE / Q8QZV6 Protein FAM161A from Mus musculus (Mouse) (see 2 papers)
Aligns to 150:336 / 475 (39.4%), covers 45.6% of PF10595, 116.7 bits
- function: Involved in ciliogenesis.
subunit: Interacts (via central region) with CFAP418 (via N-terminus); the interaction is direct (By similarity). Interacts (via C-terminus) with microtubules (By similarity). Interacts with LCA5 (By similarity). Interacts with CEP290 (By similarity). Interacts with SDCCAG8 (By similarity). Interacts with FAM161B (By similarity). Interacts with POC1B (By similarity). Interacts with CEP78 (By similarity).
F161A_RAT / Q6AY14 Protein FAM161A from Rattus norvegicus (Rat) (see paper)
Aligns to 170:378 / 474 (44.1%), covers 44.5% of PF10595, 114.6 bits
- function: Involved in ciliogenesis.
subunit: Interacts (via central region) with CFAP418 (via N-terminus); the interaction is direct (By similarity). Interacts (via C-terminus) with microtubules (By similarity). Interacts with LCA5 (By similarity). Interacts with CEP290 (By similarity). Interacts with SDCCAG8 (By similarity). Interacts with FAM161B (By similarity). Interacts with POC1B (By similarity). Interacts with CEP78 (By similarity).
Or search for genetic data about PF10595 in the Fitness Browser
by Morgan Price,
Arkin group
Lawrence Berkeley National Laboratory