Family Search for PF12015 (Bud3_N)

April 2024: GapMind for amino acid biosynthesis has been updated to include newly-discovered enzymes and comparative genomics predictions (see details)

Running HMMer for PF12015

PF12015 hits 3 sequences in PaperBLAST's database above the trusted cutoff. Showing all hits. Or show only hits to curated sequences or try another family.

BUD3_YEAST / P25558 Bud site selection protein 3 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
YCL014W Bud3p from Saccharomyces cerevisiae
NP_009914 Bud3p from Saccharomyces cerevisiae S288C
Aligns to 27:205 / 1636 (10.9%), covers 99.5% of PF12015, 242.2 bits

• function: Co-assembles with BUD4 at bud sites. BUD4 and BUD3 may cooperate to recognize a spatial landmark (the neck filaments) during mitosis and they subsequently become a landmark for establishing the axial budding pattern in G1
  subunit: Interacts with AXL2.
• Ecological success of a group of Saccharomyces cerevisiae/Saccharomyces kudriavzevii hybrids in the northern european wine-making environment
  Erny, Applied and environmental microbiology 2012
  • “...13 14 15 16 YAL008W YBL021C SK_YCR093w YCL014w YDL003W YDR337fw YEL061wfw YER073w (HE585129) YFR030W SK_YGL035 YGL162W YHL038c YHR043C YIL013C SK_YJL206c...”
  • “...are indicated by an "SK_" prefix. For the locus YCL014w, ARD6.1 (a French isolate) was used in place of IFO1802 as a reference. b Sk, Saccharomyces...”
• Differential selection on gene translation efficiency between the filamentous fungus Ashbya gossypii and yeasts
  Jiang, BMC evolutionary biology 2008
  • “...2005 [ 43 ] AgSPA2 YLL021W 0.812361 Knechtle et al. 2003 [ 44 ] AgBUD3 YCL014W 0.821338 Wendland 2003 [ 45 ] AgCYK1 YPL242C 0.90517 Wendland 2002 [ 46 ] a: Comparison of tAI values between A. gossypii and other yeast species. Discussion Codon usage bias...”
• Yeast genomic expression patterns in response to low-shear modeled microgravity
  Sheehan, BMC genomics 2007
  • “...selection BUD17 YNR027W 1.2 1.0 bud site selection RRP14 YKL082C 1.3 1.4 cell polarity BUD3 YCL014W 1.3 1.4 bud site selection BUD31 YCR063W 1.4 1.3 bud site selection BUD6 YLR319C 1.4 1.4 bud site selection AXL2 YIL140W 1.4 1.4 bud site selection HKR1 YDR420W 1.5 1.7...”
• Improving comparability between microarray probe signals by thermodynamic intensity correction
  Bruun, Nucleic acids research 2007
  • “...YBL002W HTB2 X 396 38 YBR093C PHO5 X 1404 138 YBR243C ALG7 X 1347 266 YCL014W BUD3 4911 489 YDL003W MCD1 1701 168 YDL224C WHI4 1950 193 YER001W MNN1 X 2289 227 YGR044C RME1 903 88 YGR108W CLB1 X 1416 140 YHR086W NAM8 1572 155 YHR175W...”
• Identification of sparsely distributed clusters of cis-regulatory elements in sets of co-expressed genes
  Kreiman, Nucleic acids research 2004
  • “...CLB2 set YLR131C ACE2 YGL021W ALK1 YNL172W APC1 YCL014W BUD3 YJR092W BUD4 YLR353W BUD8 YGL116W CDC20 YMR001C CDC5 YBR038W CHS2 YGR108W CLB1 YPR119W CLB2...”
• Combined analysis of expression data and transcription factor binding sites in the yeast genome
  Nagaraj, BMC genomics 2004
  • “...0.4390 0.0010 - YLR080W EMP46 0.0024 0.6757 0.0016 - YIR039C YPS6 0.0025 0.7843 0.0020 - YCL014W BUD3 0.0027 0.3475 0.0009 - YPL189W GUP2 0.0030 0.3708 0.0011 - YJL077C ICS3 0.0032 0.9540 0.0030 - YML042W CAT2 0.0033 0.7564 0.0025 - YHR004C NEM1 0.0035 0.6396 0.0022 + YFR046C...”
• Identification of stop codon readthrough genes in Saccharomyces cerevisiae
  Namy, Nucleic acids research 2003
  • “...to verify that no error occurred during PCR amplification. Among the 60 SORFs analyzed, two (YCL014w and YJL162c) did not show the presence of the expected stop codon. Since the strain used here (Y349) is not the SC288C strain that has been used for the yeast...”
  • “...YAL019W 570 3495 YAL021C 2514 228 YAL024C 4308 216 YAR066W 612 1284 YCL006C 330 246 YCL014W 4104 807 YCL022C 515 570 YCL074W 927 291 YDL037C 987 2271 YDL050C 372 378 YDR082W 1485 1299 YDR275W 708 216 YDR509W 348 348 YER039Ca 237 807 YER109C 426 1974 YFL052W...”
• Genetic analysis reveals that FLO11 upregulation and cell polarization independently regulate invasive growth in Saccharomyces cerevisiae
  Palecek, Genetics 2000
  • “...Mutant allele Insertion sitea Haploid invasion SEMb BUD3 YCL014W YJR092W BUD10 YIL140W AXL1 BEM2 ELM1 HSL1 HSL7 YDJ1 YPR122W YER155C YKL048C YKL101W YBR133C...”
• Critical Roles of a RhoGEF-Anillin Module in Septin Architectural Remodeling during Cytokinesis.
  Chen, Current biology : CB 2020
  • GeneRIF: Critical Roles of a RhoGEF-Anillin Module in Septin Architectural Remodeling during Cytokinesis.
• Bud3 activates Cdc42 to establish a proper growth site in budding yeast.
  Kang, The Journal of cell biology 2014
  • GeneRIF: Cell polarization in Saccharomyces cerevisiae, to a proper growth site, requires activation of Cdc42 by Bud3.

BUD3_EREGS / Q9HF61 Bud site selection protein 3 homolog from Eremothecium gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056) (Yeast) (Ashbya gossypii) (see paper)
Aligns to 18:189 / 1478 (11.6%), covers 95.1% of PF12015, 228.1 bits

• function: Required for proper septum positioning and septum construction during septation. Acts as a landmark to mark sites for future septation, and as part of a scaffold that recruits components of the contractile ring to the site of septation. Not required to determine the site of lateral branch formation.

bud3 Rho guanyl nucleotide exchange factor from Emericella nidulans (see paper)
Aligns to 13:170 / 1511 (10.5%), covers 69.8% of PF12015, 33.1 bits

• CharProtDB Description: Putative Rho guanyl nucleotide exchange factor (Rho-GEF); required for septum formation; Source:AspGD

Or search for genetic data about PF12015 in the Fitness Browser