Family Search for PF12263 (DUF3611)

April 2024: See Interactive Tools for Functional Annotation of Bacterial Genomes for advice on using these tools.

PF12263 hits 6 sequences in PaperBLAST's database above the trusted cutoff. Showing hits to curated sequences only. Or see all hits or try another family.

TIC21_ARATH / Q9SHU7 Protein TIC 21, chloroplastic; Protein CHLOROPLAST IMPORT APPARATUS 5; AtCIA5; Protein PERMEASE IN CHLOROPLASTS 1; AtPIC1; Translocon at the inner envelope membrane of chloroplasts 21; AtTIC21 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
Aligns to 107:283 / 296 (59.8%), covers 98.9% of PF12263, 179.4 bits

• function: Involved in chloroplast protein import across the inner envelope membrane. Acts also as a chloroplast permease regulating the iron transport and homeostasis. Involved in the uptake and sequestration of iron in plastids.
  subunit: Homomultimer. Part of the translocon complex.
  disruption phenotype: Seedling lethal when grown on soil. Albino or chlorotic dwarfed plants that accumulate unprocessed precursor proteins and chloroplast ferritin clusters when grown in vitro.

Or search for genetic data about PF12263 in the Fitness Browser