# Candidate

orgId: FitnessBrowser__ANA3
pathwayId: arg
stepId: argA
locusId: 7026634
sysName: Shewana3_3767
desc: N-acetylglutamate synthase (RefSeq)
hmmId: TIGR01890
hmmDesc: argA: amino-acid N-acetyltransferase (EC 2.3.1.1)
otherIds: BRENDA::Q6V1L5
curatedIds:
CharProtDB::CH_024150,SwissProt::P0A6C5,ecocyc::N-ACETYLTRANSFER-MONOMER,metacyc::N-ACETYLTRANSFER-MONOMER


orgId: FitnessBrowser__ANA3
pathwayId: arg
stepId: argB
locusId: 7026772
sysName: Shewana3_3904
desc: acetylglutamate kinase (RefSeq)
hmmId: TIGR00761
hmmDesc: argB: acetylglutamate kinase (EC 2.7.2.8)
curatedIds:
BRENDA::A0A140NEG9,CharProtDB::CH_001694,SwissProt::P0A6C8,ecocyc::ACETYLGLUTKIN-MONOMER,metacyc::ACETYLGLUTKIN-MONOMER


orgId: FitnessBrowser__ANA3
pathwayId: arg
stepId: argC
locusId: 7026773
sysName: Shewana3_3905
desc: N-acetyl-gamma-glutamyl-phosphate reductase (RefSeq)
hmmId: TIGR01850
hmmDesc: argC: N-acetyl-gamma-glutamyl-phosphate reductase (EC 1.2.1.38)
otherIds: BRENDA::C7ACH5
curatedIds:
BRENDA::P11446,SwissProt::P11446,ecocyc::N-ACETYLGLUTPREDUCT-MONOMER,metacyc::N-ACETYLGLUTPREDUCT-MONOMER


orgId: FitnessBrowser__ANA3
pathwayId: arg
stepId: argD
locusId: 7023380
sysName: Shewana3_0610
curatedIds: BRENDA::O30508,SwissProt::O30508,metacyc::MONOMER-11526
desc:
bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein (RefSeq)


orgId: FitnessBrowser__ANA3
pathwayId: chorismate
stepId: tpiA
locusId: 7023804
sysName: Shewana3_1026
desc: triosephosphate isomerase (RefSeq)
hmmId: TIGR00419
hmmDesc: tpiA: triose-phosphate isomerase (EC 5.3.1.1)
curatedIds:
BRENDA::P0A858,CharProtDB::CH_024675,SwissProt::B1XB85,SwissProt::P0A858,ecocyc::TPI-MONOMER,metacyc::TPI-MONOMER


orgId: FitnessBrowser__ANA3
pathwayId: cys
stepId: CBS
locusId: 7024369
sysName: Shewana3_1561
desc: cysteine synthase (RefSeq)
curatedIds: metacyc::HP_RS00545-MONOMER
otherIds:
BRENDA::P0ABK5,CharProtDB::CH_024343,SwissProt::P0ABK5,ecocyc::ACSERLYA-MONOMER,metacyc::ACSERLYA-MONOMER


orgId: FitnessBrowser__ANA3
pathwayId: cys
stepId: CGL
locusId: 7025253
sysName: Shewana3_2414
desc: cystathionine beta-lyase (RefSeq)
curatedIds: metacyc::HP_RS00540-MONOMER
otherIds:
BRENDA::P06721,SwissProt::P06721,ecocyc::CYSTATHIONINE-BETA-LYASE-MONOMER,metacyc::CYSTATHIONINE-BETA-LYASE-MONOMER


orgId: FitnessBrowser__ANA3
pathwayId: cys
stepId: moeZ
locusId: 7022880
sysName: Shewana3_0130
desc: molybdopterin biosynthesis protein MoeB (RefSeq)
curatedIds: SwissProt::P9WMN7,metacyc::G185E-7476-MONOMER
otherIds:
BRENDA::P12282,CharProtDB::CH_002527,SwissProt::P12282,ecocyc::EG10154-MONOMER,metacyc::EG10154-MONOMER


orgId: FitnessBrowser__ANA3
pathwayId: cys
stepId: serA
locusId: 7026274
sysName: Shewana3_3416
desc: D-3-phosphoglycerate dehydrogenase (RefSeq)
curatedIds:
BRENDA::C3SVM7,BRENDA::P0A9T0,CharProtDB::CH_088336,SwissProt::P0A9T0,ecocyc::PGLYCDEHYDROG-MONOMER,metacyc::PGLYCDEHYDROG-MONOMER


orgId: FitnessBrowser__ANA3
pathwayId: cys
stepId: serC
locusId: 7024795
sysName: Shewana3_1973
desc: phosphoserine aminotransferase (RefSeq)
hmmId: TIGR01364
hmmDesc: serC: phosphoserine transaminase (EC 2.6.1.52)
curatedIds:
BRENDA::P23721,CharProtDB::CH_002572,SwissProt::P23721,ecocyc::PSERTRANSAM-MONOMER,metacyc::PSERTRANSAM-MONOMER


orgId: FitnessBrowser__ANA3
pathwayId: his
stepId: hisA
locusId: 7024671
sysName: Shewana3_1849
curatedIds: BRENDA::P10372
hmmId: TIGR00007
desc:
1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase (RefSeq)

hmmDesc:
hisA: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase (EC 5.3.1.16)


orgId: FitnessBrowser__ANA3
pathwayId: his
stepId: hisG
locusId: 7024676
sysName: Shewana3_1854
desc: ATP phosphoribosyltransferase (RefSeq)
hmmId: TIGR00070
hmmDesc: hisG: ATP phosphoribosyltransferase (EC 2.4.2.17)
curatedIds:
CharProtDB::CH_024688,SwissProt::P60757,ecocyc::ATPPHOSRIBOSTRANS-MONOMER,metacyc::ATPPHOSRIBOSTRANS-MONOMER


orgId: FitnessBrowser__ANA3
pathwayId: his
stepId: hisH
locusId: 7024672
sysName: Shewana3_1850
desc: imidazole glycerol phosphate synthase subunit HisH (RefSeq)
hmmId: TIGR01855
hmmDesc: hisH: imidazole glycerol phosphate synthase, glutamine amidotransferase subunit (EC 2.4.2.-)
curatedIds:
CharProtDB::CH_024511,SwissProt::P60595,ecocyc::GLUTAMIDOTRANS-MONOMER,metacyc::GLUTAMIDOTRANS-MONOMER


orgId: FitnessBrowser__ANA3
pathwayId: ile
stepId: ilvD
locusId: 7023120
sysName: Shewana3_0358
desc: dihydroxy-acid dehydratase (RefSeq)
hmmId: TIGR00110
hmmDesc: ilvD: dihydroxy-acid dehydratase (EC 4.2.1.9)
curatedIds:
CharProtDB::CH_024768,SwissProt::P05791,ecocyc::DIHYDROXYACIDDEHYDRAT-MONOMER,metacyc::DIHYDROXYACIDDEHYDRAT-MONOMER


orgId: FitnessBrowser__ANA3
pathwayId: ile
stepId: ilvD
locusId: 7024978
sysName: Shewana3_2149
desc: phosphogluconate dehydratase (RefSeq)
curatedIds: curated2:A8AB39
otherIds:
CharProtDB::CH_024239,SwissProt::P0ADF6,ecocyc::PGLUCONDEHYDRAT-MONOMER,metacyc::PGLUCONDEHYDRAT-MONOMER


orgId: FitnessBrowser__ANA3
pathwayId: ile
stepId: ilvH
locusId: 7025107
sysName: Shewana3_2270
desc: acetolactate synthase 3 regulatory subunit (RefSeq)
hmmId: TIGR00119
hmmDesc: ilvN: acetolactate synthase, small subunit (EC 2.2.1.6)
curatedIds:
BRENDA::P00894,CharProtDB::CH_002163,ecocyc::ACETOLACTSYNIII-HCHAIN-MONOMER,metacyc::ACETOLACTSYNIII-HCHAIN-MONOMER


orgId: FitnessBrowser__ANA3
pathwayId: lys
stepId: dapB
locusId: 7023736
sysName: Shewana3_0966
desc: dihydrodipicolinate reductase (RefSeq)
hmmId: TIGR00036
hmmDesc: dapB: 4-hydroxy-tetrahydrodipicolinate reductase (EC 1.17.1.8)
curatedIds:
CharProtDB::CH_002128,SwissProt::P04036,ecocyc::DIHYDROPICRED-MONOMER,metacyc::DIHYDROPICRED-MONOMER


orgId: FitnessBrowser__ANA3
pathwayId: lys
stepId: dapH
locusId: 7025324
sysName: Shewana3_2484
desc: hexapaptide repeat-containing transferase (RefSeq)
curatedIds: curated2:Q9K9H8
otherIds:
CharProtDB::CH_088634,SwissProt::P77791,ecocyc::MALTACETYLTRAN-MONOMER,metacyc::MALTACETYLTRAN-MONOMER


orgId: FitnessBrowser__ANA3
pathwayId: met
stepId: metH
locusId: 7026140
sysName: Shewana3_3282
desc: B12-dependent methionine synthase (RefSeq)
hmmId: TIGR02082
hmmDesc: metH: methionine synthase (EC 2.1.1.13)
curatedIds:
CharProtDB::CH_090726,SwissProt::P13009,ecocyc::HOMOCYSMETB12-MONOMER,metacyc::HOMOCYSMETB12-MONOMER


orgId: FitnessBrowser__ANA3
pathwayId: phe
stepId: PPYAT
locusId: 7024947
sysName: Shewana3_2121
desc: aromatic amino acid aminotransferase (RefSeq)
curatedIds:
BRENDA::A0A140ND68,BRENDA::D3H0F7,BRENDA::P00509,SwissProt::P00509,ecocyc::ASPAMINOTRANS-MONOMER,metacyc::ASPAMINOTRANS-MONOMER


orgId: FitnessBrowser__ANA3
pathwayId: phe
stepId: cmutase
locusId: 7025858
sysName: Shewana3_3007
desc: chorismate mutase / prephenate dehydratase (RefSeq)
hmmId: TIGR01797
hmmDesc: chorismate mutase (EC 5.4.99.5)
curatedIds:
CharProtDB::CH_024084,SwissProt::P0A9J8,ecocyc::CHORISMUTPREPHENDEHYDRAT-MONOMER,metacyc::CHORISMUTPREPHENDEHYDRAT-MONOMER


orgId: FitnessBrowser__ANA3
pathwayId: pro
stepId: proB
locusId: 7023724
sysName: Shewana3_0954
desc: gamma-glutamyl kinase (RefSeq)
hmmId: TIGR01027
hmmDesc: proB: glutamate 5-kinase (EC 2.7.2.11)
curatedIds:
BRENDA::P0A7B5,CharProtDB::CH_108540,SwissProt::P0A7B5,ecocyc::GLUTKIN-MONOMER,metacyc::GLUTKIN-MONOMER


orgId: FitnessBrowser__ANA3
pathwayId: thr
stepId: thrC
locusId: 7023929
sysName: Shewana3_1141
desc: threonine synthase (RefSeq)
hmmId: TIGR00260
hmmDesc: thrC: threonine synthase (EC 4.2.3.1)
otherIds: SwissProt::Q86YJ6
curatedIds:
BRENDA::P00934,CharProtDB::CH_002114,SwissProt::P00934,ecocyc::THRESYN-MONOMER,metacyc::THRESYN-MONOMER


orgId: FitnessBrowser__ANA3
pathwayId: trp
stepId: trpD_1
locusId: 7024028
sysName: Shewana3_1236
desc: GMP synthase (RefSeq)
curatedIds: curated2:O28670
otherIds:
BRENDA::P04079,CharProtDB::CH_003303,SwissProt::P04079,ecocyc::GMP-SYN-MONOMER,metacyc::GMP-SYN-MONOMER


orgId: FitnessBrowser__ANA3
pathwayId: trp
stepId: trpE
locusId: 7025140
sysName: Shewana3_2303
desc: aminodeoxychorismate synthase, subunit I (RefSeq)
curatedIds: curated2:Q9X6J4
otherIds:
CharProtDB::CH_002963,SwissProt::P05041,ecocyc::PABASYN-COMPI-MONOMER,metacyc::PABASYN-COMPI-MONOMER


orgId: FitnessBrowser__BFirm
pathwayId: lys
stepId: lysA
locusId: BPHYT_RS35090
sysName: BPHYT_RS35090
desc: diaminopimelate decarboxylase
hmmId: TIGR01048
hmmDesc: lysA: diaminopimelate decarboxylase (EC 4.1.1.20)
curatedIds:
BRENDA::P00861,SwissProt::E0IWI3,SwissProt::P00861,ecocyc::DIAMINOPIMDECARB-MONOMER,metacyc::DIAMINOPIMDECARB-MONOMER


orgId: FitnessBrowser__Btheta
pathwayId: his
stepId: hisA
locusId: 350907
sysName: BT1379
curatedIds: reanno::Btheta:350907
hmmId: TIGR00007
desc:
phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase (NCBI ptt file)

hmmDesc:
hisA: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase (EC 5.3.1.16)


orgId: FitnessBrowser__Caulo
pathwayId: phe
stepId: PPYAT
locusId: CCNA_03024
sysName: CCNA_03024
desc: branched-chain amino acid aminotransferase
curatedIds:
CharProtDB::CH_024500,ecocyc::BRANCHED-CHAINAMINOTRANSFER-MONOMER,metacyc::BRANCHED-CHAINAMINOTRANSFER-MONOMER


orgId: FitnessBrowser__Caulo
pathwayId: trp
stepId: trpD_1
locusId: CCNA_01974
sysName: CCNA_01974
curatedIds: SwissProt::P26922
hmmId: TIGR00566
hmmDesc: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase
desc:
anthranilate synthase component II/para-aminobenzoate synthase glutamine amidotransferase component II


orgId: FitnessBrowser__Cola
pathwayId: trp
stepId: trpD_1
locusId: Echvi_0152
sysName: Echvi_0152
curatedIds: BRENDA::P09786,SwissProt::P09786,metacyc::MONOMER-16008
desc:
GMP synthase (glutamine-hydrolyzing), C-terminal domain or B subunit/GMP synthase (glutamine-hydrolyzing), N-terminal domain or A subunit


orgId: FitnessBrowser__Cup4G11
pathwayId: arg
stepId: argD
locusId: RR42_RS16955
sysName: RR42_RS16955
desc: acetylornithine aminotransferase
curatedIds:
CharProtDB::CH_002469,SwissProt::P77581,ecocyc::SUCCORNTRANSAM-MONOMER,metacyc::SUCCORNTRANSAM-MONOMER


orgId: FitnessBrowser__Cup4G11
pathwayId: phe
stepId: ptransferase
locusId: RR42_RS12545
sysName: RR42_RS12545
desc: aminotransferase
curatedIds: SwissProt::A3PMF8
otherIds:
BRENDA::D2AFZ3,BRENDA::P0A959,CharProtDB::CH_024885,SwissProt::P0A959,ecocyc::G7184-MONOMER,metacyc::G7184-MONOMER


orgId: FitnessBrowser__Dyella79
pathwayId: ile
stepId: prpE
locusId: N515DRAFT_1417
sysName: N515DRAFT_1417
desc: long-chain acyl-CoA synthetase
curatedIds: SwissProt::M4IQQ5,metacyc::MONOMER-20125
otherIds:
CharProtDB::CH_000804,SwissProt::P69451,TCDB::P69451,ecocyc::ACYLCOASYN-MONOMER,metacyc::ACYLCOASYN-MONOMER


orgId: FitnessBrowser__Dyella79
pathwayId: lys
stepId: dapH
locusId: N515DRAFT_4103
sysName: N515DRAFT_4103
curatedIds: curated2:C4L2D4
otherIds: BRENDA::Q2P7P9
desc:
bifunctional UDP-N-acetylglucosamine pyrophosphorylase / Glucosamine-1-phosphate N-acetyltransferase


orgId: FitnessBrowser__Keio
pathwayId: chorismate
stepId: aroE
locusId: 15811
sysName: b1692
desc: quinate/shikimate 5-dehydrogenase, NAD(P)-binding (NCBI)
otherIds: metacyc::MONOMER-21745
curatedIds:
BRENDA::P0A6D5,CharProtDB::CH_024574,SwissProt::P0A6D5,ecocyc::EG11234-MONOMER,metacyc::EG11234-MONOMER


orgId: FitnessBrowser__Keio
pathwayId: chorismate
stepId: asd
locusId: 17495
sysName: b3433
desc: aspartate-semialdehyde dehydrogenase (NCBI)
hmmId: TIGR01745
hmmDesc: asd: aspartate-semialdehyde dehydrogenase (EC 1.2.1.11)
curatedIds:
CharProtDB::CH_024631,SwissProt::P0A9Q9,ecocyc::ASP-SEMIALDEHYDE-DEHYDROGENASE-MONOMER,metacyc::ASP-SEMIALDEHYDE-DEHYDROGENASE-MONOMER


orgId: FitnessBrowser__Keio
pathwayId: chorismate
stepId: fbp
locusId: 17004
sysName: b2925
desc: fructose-bisphosphate aldolase (NCBI)
hmmId: TIGR01520
hmmDesc: fbaA: fructose-bisphosphate aldolase, class II (EC 4.1.2.13)
curatedIds:
CharProtDB::CH_024118,SwissProt::P0AB71,ecocyc::FRUCTBISALD-CLASSII-MONOMER,metacyc::FRUCTBISALD-CLASSII-MONOMER


orgId: FitnessBrowser__Keio
pathwayId: chorismate
stepId: fbp
locusId: 17210
sysName: b3137
desc: tagatose 6-phosphate aldolase 1, kbaY subunit (NCBI)
curatedIds: SwissProt::Q703I2
otherIds:
CharProtDB::CH_024465,SwissProt::P0AB74,ecocyc::TAGAALDOL1-MONOMER,metacyc::MONOMER-18279,metacyc::TAGAALDOL1-MONOMER


orgId: FitnessBrowser__Keio
pathwayId: cys
stepId: cysE
locusId: 17668
sysName: b3607
desc: serine acetyltransferase (NCBI)
hmmId: TIGR01172
hmmDesc: cysE: serine O-acetyltransferase (EC 2.3.1.30)
curatedIds:
BRENDA::P0A9D4,CharProtDB::CH_024412,SwissProt::P0A9D4,ecocyc::SERINE-O-ACETTRAN-MONOMER,metacyc::SERINE-O-ACETTRAN-MONOMER


orgId: FitnessBrowser__Keio
pathwayId: cys
stepId: cysE
locusId: 18041
sysName: b4013
desc: homoserine O-succinyltransferase (NCBI)
curatedIds: SwissProt::A0A1D3PCK2
otherIds:
BRENDA::P07623,CharProtDB::CH_004029,SwissProt::P07623,ecocyc::HOMSUCTRAN-MONOMER,metacyc::HOMSUCTRAN-MONOMER


orgId: FitnessBrowser__Keio
pathwayId: cys
stepId: cysE
locusId: 14480
sysName: b0342
desc: galactoside O-acetyltransferase (NCBI)
curatedIds: BRENDA::Q6F4D7
otherIds:
BRENDA::P07464,SwissProt::P07464,ecocyc::GALACTOACETYLTRAN-MONOMER,metacyc::GALACTOACETYLTRAN-MONOMER


orgId: FitnessBrowser__Keio
pathwayId: gly
stepId: glyA
locusId: 16650
sysName: b2551
desc: serine hydroxymethyltransferase (NCBI)
curatedIds:
BRENDA::P0A825,CharProtDB::CH_024268,SwissProt::P0A825,ecocyc::GLYOHMETRANS-MONOMER,metacyc::GLYOHMETRANS-MONOMER


orgId: FitnessBrowser__Keio
pathwayId: his
stepId: hisA
locusId: 16132
sysName: b2024
curatedIds: ecocyc::PRIBFAICARPISOM-MONOMER,metacyc::PRIBFAICARPISOM-MONOMER
hmmId: TIGR00007
desc:
N-(5'-phospho-L-ribosyl-formimino)-5-amino-1-(5'- phosphoribosyl)-4-imidazolecarboxamide isomerase (VIMSS)


orgId: FitnessBrowser__Keio
pathwayId: ile
stepId: ilvC
locusId: 17826
sysName: b3774
desc: ketol-acid reductoisomerase (NCBI)
hmmId: TIGR00465
hmmDesc: ilvC: ketol-acid reductoisomerase (EC 1.1.1.86)
curatedIds:
BRENDA::P05793,CharProtDB::CH_003903,SwissProt::P05793,ecocyc::KETOLREDUCTOISOM-MONOMER,metacyc::KETOLREDUCTOISOM-MONOMER


orgId: FitnessBrowser__Keio
pathwayId: ile
stepId: leuB
locusId: 14219
sysName: b0073
desc: 3-isopropylmalate dehydrogenase (VIMSS)
hmmId: TIGR00169
hmmDesc: leuB: 3-isopropylmalate dehydrogenase (EC 1.1.1.85)
curatedIds:
BRENDA::P30125,SwissProt::P30125,ecocyc::3-ISOPROPYLMALDEHYDROG-MONOMER,metacyc::3-ISOPROPYLMALDEHYDROG-MONOMER


orgId: FitnessBrowser__Keio
pathwayId: ile
stepId: leuC
locusId: 15396
sysName: b1276
desc: aconitate hydratase (NCBI)
curatedIds: curated2:Q9WZ24
otherIds:
BRENDA::P25516,CharProtDB::CH_002745,SwissProt::P25516,ecocyc::ACONITASE-MONOMER,metacyc::ACONITASE-MONOMER


orgId: FitnessBrowser__Keio
pathwayId: lys
stepId: dapA
locusId: 17296
sysName: b3225
desc: N-acetylneuraminate lyase (NCBI)
curatedIds: BRENDA::Q6G468
otherIds:
BRENDA::P0A6L4,CharProtDB::CH_024068,SwissProt::P0A6L4,ecocyc::ACNEULY-MONOMER,metacyc::ACNEULY-MONOMER


orgId: FitnessBrowser__Keio
pathwayId: pro
stepId: proC
locusId: 14524
sysName: b0386
desc: pyrroline-5-carboxylate reductase (NCBI)
hmmId: TIGR00112
hmmDesc: proC: pyrroline-5-carboxylate reductase (EC 1.5.1.2)
curatedIds:
CharProtDB::CH_024367,SwissProt::P0A9L8,ecocyc::PYRROLINECARBREDUCT-MONOMER,metacyc::PYRROLINECARBREDUCT-MONOMER


orgId: FitnessBrowser__Keio
pathwayId: val
stepId: ilvE
locusId: 1937060
sysName: b3572
desc: valine--pyruvate transaminase (NCBI)
curatedIds:
BRENDA::P09053,SwissProt::P09053,ecocyc::VALINE-PYRUVATE-AMINOTRANSFER-MONOMER,metacyc::VALINE-PYRUVATE-AMINOTRANSFER-MONOMER


orgId: FitnessBrowser__Korea
pathwayId: his
stepId: hisA
locusId: Ga0059261_1047
sysName: Ga0059261_1047
curatedIds: reanno::Korea:Ga0059261_1047
hmmId: TIGR00007
desc:
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase (EC 5.3.1.16)


orgId: FitnessBrowser__Korea
pathwayId: ile
stepId: ilvE
locusId: Ga0059261_3317
sysName: Ga0059261_3317
curatedIds: reanno::acidovorax_3H11:Ac3H11_1358
otherIds: BRENDA::Q72LL6,SwissProt::Q72LL6
desc:
Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs


orgId: FitnessBrowser__Korea
pathwayId: ile
stepId: ilvI
locusId: Ga0059261_0285
sysName: Ga0059261_0285
curatedIds: SwissProt::P0DP90,CharProtDB::CH_003896
otherIds: BRENDA::B1XMM5,metacyc::MONOMER-17040
desc:
Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase]


orgId: FitnessBrowser__Marino
pathwayId: ile
stepId: ilvI
locusId: GFF974
sysName: HP15_953
curatedIds: curated2:O53554
desc:
protein containing thiamine pyrophosphate enzyme, C-terminal TPP-binding / Thiamine pyrophosphate enzyme, N-terminal TPP binding region


orgId: FitnessBrowser__Marino
pathwayId: ile
stepId: leuC
locusId: GFF2253
sysName: HP15_2203
desc: bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase
curatedIds: curated2:O27439
otherIds:
BRENDA::P36683,CharProtDB::CH_002191,SwissProt::P36683,ecocyc::ACONITATEDEHYDRB-MONOMER,metacyc::ACONITATEDEHYDRB-MONOMER


orgId: FitnessBrowser__Phaeo
pathwayId: his
stepId: hisA
locusId: GFF911
sysName: PGA1_c09270
curatedIds: reanno::Smeli:SMc02570
hmmId: TIGR00007
desc:
1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase HisA


orgId: FitnessBrowser__Phaeo
pathwayId: his
stepId: hisA
locusId: GFF1767
sysName: PGA1_c17910
curatedIds: reanno::Caulo:CCNA_03852
desc:
1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase-like protein


orgId: FitnessBrowser__SB2B
pathwayId: cys
stepId: serA
locusId: 6938020
sysName: Sama_2153
desc: erythronate-4-phosphate dehydrogenase (RefSeq)
curatedIds: BRENDA::A4VGK3
otherIds:
BRENDA::P05459,SwissProt::P05459,ecocyc::ERYTHRON4PDEHYDROG-MONOMER,metacyc::ERYTHRON4PDEHYDROG-MONOMER


orgId: FitnessBrowser__Smeli
pathwayId: lys
stepId: dapH
locusId: SMc00232
sysName: SMc00232
curatedIds: curated2:B1L0V4
desc:
bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase

otherIds:
BRENDA::P0ACC7,CharProtDB::CH_014350,SwissProt::P0ACC7,ecocyc::NAG1P-URIDYLTRANS-MONOMER,metacyc::NAG1P-URIDYLTRANS-MONOMER


orgId: FitnessBrowser__SynE
pathwayId: lys
stepId: dapH
locusId: Synpcc7942_0931
sysName: Synpcc7942_0931
desc: UDP-N-acetylglucosamine acyltransferase
curatedIds: curated2:Q9K9H8
otherIds:
CharProtDB::CH_024383,SwissProt::P0A722,ecocyc::UDPNACETYLGLUCOSAMACYLTRANS-MONOMER,metacyc::UDPNACETYLGLUCOSAMACYLTRANS-MONOMER


orgId: FitnessBrowser__acidovorax_3H11
pathwayId: asn
stepId: gatA
locusId: Ac3H11_3338
curatedIds: SwissProt::O06491,metacyc::MONOMER-13955
hmmId: TIGR00132
hmmDesc: gatA: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, A subunit (EC 6.3.5.-)
desc:
Aspartyl-tRNA(Asn) amidotransferase subunit A (EC 6.3.5.6) @ Glutamyl-tRNA(Gln) amidotransferase subunit A (EC 6.3.5.7)


orgId: FitnessBrowser__acidovorax_3H11
pathwayId: asn
stepId: gatB
locusId: Ac3H11_3339
curatedIds: metacyc::MONOMER-13956
hmmId: TIGR00133
hmmDesc: gatB: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, B subunit (EC 6.3.5.-)
desc:
Aspartyl-tRNA(Asn) amidotransferase subunit B (EC 6.3.5.6) @ Glutamyl-tRNA(Gln) amidotransferase subunit B (EC 6.3.5.7)


orgId: FitnessBrowser__acidovorax_3H11
pathwayId: asn
stepId: gatC
locusId: Ac3H11_3337
curatedIds: curated2:Q12H06
hmmId: TIGR00135
hmmDesc: gatC: aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase, C subunit (EC 6.3.5.-)
desc:
Aspartyl-tRNA(Asn) amidotransferase subunit C (EC 6.3.5.6) @ Glutamyl-tRNA(Gln) amidotransferase subunit C (EC 6.3.5.7)


orgId: FitnessBrowser__acidovorax_3H11
pathwayId: cys
stepId: serA
locusId: Ac3H11_2599
curatedIds: curated2:O27051
otherIds: BRENDA::F8AEA4
desc:
Glyoxylate reductase (EC 1.1.1.79) / Glyoxylate reductase (EC 1.1.1.26) / Hydroxypyruvate reductase (EC 1.1.1.81); 2-ketoaldonate reductase, broad specificity (EC 1.1.1.215) (EC 1.1.1.-)


orgId: FitnessBrowser__acidovorax_3H11
pathwayId: ile
stepId: leuB
locusId: Ac3H11_3259
curatedIds: BRENDA::P76251,CharProtDB::CH_008421,SwissProt::P76251,ecocyc::G6986-MONOMER,metacyc::G6986-MONOMER
otherIds: SwissProt::Q51945,metacyc::MONOMER-12928
desc:
Tartrate dehydrogenase (EC 1.1.1.93) @ Tartrate decarboxylase (EC 4.1.1.73) @ D-malic enzyme (EC 1.1.1.83)


orgId: FitnessBrowser__acidovorax_3H11
pathwayId: trp
stepId: trpD_1
locusId: Ac3H11_769
curatedIds: SwissProt::P00901
hmmId: TIGR00566
hmmDesc: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase
desc:
Anthranilate synthase, amidotransferase component (EC 4.1.3.27) @ Para-aminobenzoate synthase, amidotransferase component (EC 2.6.1.85)


orgId: FitnessBrowser__acidovorax_3H11
pathwayId: trp
stepId: trpE
locusId: Ac3H11_3836
curatedIds: curated2:Q9Y8T0
otherIds: CharProtDB::CH_014435
desc:
Para-aminobenzoate synthase, aminase component (EC 2.6.1.85) / Aminodeoxychorismate lyase (EC 4.1.3.38)


orgId: FitnessBrowser__pseudo13_GW456_L13
pathwayId: arg
stepId: argD
locusId: PfGW456L13_494
curatedIds: SwissProt::P22256,ecocyc::GABATRANSAM-MONOMER,metacyc::GABATRANSAM-MONOMER
desc:
5-aminovalerate aminotransferase (EC 2.6.1.48) / Gamma-aminobutyrate:alpha-ketoglutarate aminotransferase (EC 2.6.1.19)


orgId: FitnessBrowser__pseudo13_GW456_L13
pathwayId: arg
stepId: lysJ
locusId: PfGW456L13_2301
curatedIds: metacyc::MONOMER-18314
otherIds: metacyc::MONOMER-15309
desc:
Pyoverdin biosynthesis protein PvdH, L-2,4-diaminobutyrate:2-oxoglutarate aminotransferase (EC 2.6.1.76)


orgId: FitnessBrowser__pseudo13_GW456_L13
pathwayId: chorismate
stepId: aroA
locusId: PfGW456L13_2178
curatedIds: BRENDA::Q83E11,SwissProt::Q83E11
hmmId: TIGR01356
hmmDesc: aroA: 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19)
desc:
Cyclohexadienyl dehydrogenase (EC 1.3.1.12)(EC 1.3.1.43) / 5-Enolpyruvylshikimate-3-phosphate synthase (EC 2.5.1.19)


orgId: FitnessBrowser__pseudo13_GW456_L13
pathwayId: ile
stepId: ilvE
locusId: PfGW456L13_3960
curatedIds: BRENDA::P04693,CharProtDB::CH_004054,SwissProt::P04693,ecocyc::TYRB-MONOMER,metacyc::TYRB-MONOMER
otherIds: BRENDA::W0PFQ7
desc:
Biosynthetic Aromatic amino acid aminotransferase alpha (EC 2.6.1.57) @ Aromatic-amino-acid aminotransferase (EC 2.6.1.57)


orgId: FitnessBrowser__pseudo1_N1B4
pathwayId: ile
stepId: ilvA
locusId: Pf1N1B4_4257
curatedIds: BRENDA::Q96GA7,SwissProt::Q96GA7,metacyc::HS06616-MONOMER
otherIds: BRENDA::A0A0X1KHE6
desc:
L-serine dehydratase, (PLP)-dependent (EC 4.3.1.17) @ Threonine dehydratase biosynthetic (EC 4.3.1.19)


orgId: FitnessBrowser__pseudo1_N1B4
pathwayId: ile
stepId: leuB
locusId: Pf1N1B4_4932
curatedIds: BRENDA::P76251,CharProtDB::CH_008421,SwissProt::P76251,ecocyc::G6986-MONOMER,metacyc::G6986-MONOMER
otherIds: SwissProt::Q51945,metacyc::MONOMER-12928
desc:
Tartrate dehydrogenase (EC 1.1.1.93) / Tartrate decarboxylase (EC 4.1.1.73) / D-malic enzyme (EC 1.1.1.83)


orgId: NCBI__GCF_000008325.1
pathwayId: lys
stepId: dapH
locusId: WP_010959387.1
sysName: MCA_RS00070
curatedIds: curated2:C4L2D4
otherIds: BRENDA::Q2P7P9
desc:
bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU


orgId: NCBI__GCF_000015305.1
pathwayId: gly
stepId: aceA
locusId: WP_011778075.1
sysName: MVAN_RS04040
desc: isocitrate lyase
hmmId: TIGR01346
hmmDesc: aceA: isocitrate lyase (EC 4.1.3.1)
curatedIds:
BRENDA::P9WKK7,SwissProt::H8EVV4,SwissProt::P0A5H4,SwissProt::P9WKK6,SwissProt::P9WKK7,metacyc::G185E-4594-MONOMER


orgId: NCBI__GCF_000015305.1
pathwayId: his
stepId: hisA
locusId: WP_036373015.1
sysName: MVAN_RS14105
curatedIds: BRENDA::P16250,SwissProt::P16250
desc:
bifunctional 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase/phosphoribosylanthranilate isomerase PriA


orgId: NCBI__GCF_000016745.1
pathwayId: chorismate
stepId: aroG
locusId: WP_011936974.1
sysName: GURA_RS00135
desc: 3-deoxy-7-phosphoheptulonate synthase
curatedIds: BRENDA::Q9WYH8
hmmId: TIGR01361
hmmDesc: aroF: 3-deoxy-7-phosphoheptulonate synthase (EC 2.5.1.54)
otherIds:
BRENDA::P0A715,CharProtDB::CH_024702,SwissProt::P0A715,ecocyc::KDO-8PSYNTH-MONOMER,metacyc::KDO-8PSYNTH-MONOMER


orgId: NCBI__GCF_000020045.1
pathwayId: met
stepId: asd-S-ferredoxin
locusId: WP_012403804.1
sysName: BPHY_RS22725
desc: formate dehydrogenase subunit beta
curatedIds: SwissProt::Q8TPT3
otherIds:
BRENDA::P0AAJ3,CharProtDB::CH_024503,SwissProt::P0AAJ3,TCDB::P0AAJ3,ecocyc::FDNH-MONOMER,metacyc::FDNH-MONOMER


orgId: NCBI__GCF_000025465.1
pathwayId: trp
stepId: trpD_1
locusId: WP_004148109.1
sysName: KVAR_RS15165
curatedIds: SwissProt::P00900
hmmId: TIGR00566
hmmDesc: glutamine amidotransferase of anthranilate synthase or aminodeoxychorismate synthase
desc:
bifunctional anthranilate synthase glutamate amidotransferase component TrpG/anthranilate phosphoribosyltransferase TrpD


orgId: NCBI__GCF_000336675.1
pathwayId: gly
stepId: glyXS
locusId: WP_007694463.1
sysName: C447_RS12600
desc: formyltetrahydrofolate deformylase
curatedIds: uniprot:Q8G509
otherIds:
BRENDA::P37051,CharProtDB::CH_002039,SwissProt::P37051,ecocyc::FORMYLTHFDEFORMYL-MONOMER,metacyc::FORMYLTHFDEFORMYL-MONOMER


orgId: NCBI__GCF_000733765.1
pathwayId: chorismate
stepId: aroE
locusId: WP_043766139.1
sysName: U743_RS05350
desc: glutamyl-tRNA reductase
curatedIds: curated2:A4ST49
otherIds:
BRENDA::P0A6X1,CharProtDB::CH_024665,SwissProt::P0A6X1,ecocyc::GLUTRNAREDUCT-MONOMER,metacyc::GLUTRNAREDUCT-MONOMER


# RequirementNotMet

orgId: NCBI__GCF_001401755.1
pathwayId: cys
ruleId: from-serine-homocysteine
requiredPathwayId: met
requiredRuleId: homocysteine
comment:
Cysteine biosynthesis via the reverse transsulfuration pathway requires homocysteine, which is an intermediate in methionine biosynthesis. Homocysteine is also an intermediate in the S-adenosylmethionine cycle, so many organisms that cannot synthesize methionine can convert it to homocysteine.


