Clusters of Characterized Proteins

Clustering the characterized proteins for dctM (L-malate TRAP transporter, large permease component DctM) in L-malate catabolism

Or see other characterized proteins similar to dctM

Or see all steps for L-malate catabolism

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Definition of dctM

• Curated sequence O07838: C4-dicarboxylate TRAP transporter large permease protein DctM. DctM, component of Tripartite dicarboxylate:H+ symporter (substrates include: fumarate, D- and L-malate, succinate, succinamide, orotate, iticonate and mesaconate)
• Curated sequence 5208943: dicarboxylate TRAP transporter (succinate, fumarate, L-malate, and alpha-ketoglutarate), large permease component
• Curated sequence Q9HU16: C4-dicarboxylate TRAP transporter large permease protein DctM
• UniProt sequence I7DRS6: SubName: Full=TRAP transporter, subunit DctM {ECO:0000313|EMBL:AFO91751.1};
• Ignore hits to 6938090 when looking for 'other' hits (alpha-ketoglutarate TRAP transporter, large permease component)
• Comment: 3-component TRAP transporter dctMPQ. In Phaeobacter inhibens, the system is important for L-malate utilization: PGA1_c20660 = dctM = I7DRS6; PGA1_c20680 = dctP = I7END8; PGA1_c20670 = dctQ = I7EY26. A very similar system is present in Shewanella amazonensis SB2B, which cannot grow on L-malate; it is still possible that this system transports L-malate, so it is marked ignore.

Fetched 4 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 4 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 427-467 amino acids (2/4 heteromeric)

DCTM_RHOCA / O07838 C4-dicarboxylate TRAP transporter large permease protein DctM from Rhodobacter capsulatus (Rhodopseudomonas capsulata)
TC 2.A.56.1.1 / O07838 DctM, component of Tripartite dicarboxylate:H+ symporter (substrates include: fumarate, D- and L-malate, succinate, succinamide, orotate, iticonate and mesaconate) from Rhodobacter capsulatus (Rhodopseudomonas capsulata)
PFams: DctM
Heteromeric, 440 amino acids: PaperBLAST, CDD, Compare to cluster

DCTM_PSEAE / Q9HU16 C4-dicarboxylate TRAP transporter large permease protein DctM from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
PFams: DctM
427 amino acids: PaperBLAST, CDD, Compare to cluster

I7DRS6 TRAP transporter, subunit DctM
467 amino acids: PaperBLAST, CDD, Compare to cluster

Shew_1444 dicarboxylate TRAP transporter (succinate, fumarate, L-malate, and alpha-ketoglutarate), large permease component from Shewanella loihica PV-4
PFams: DctM
Heteromeric, 465 amino acids: PaperBLAST, CDD, Compare to cluster