Clusters of Characterized Proteins

Clustering the characterized proteins for deh (acetate/haloacid transporter) in acetate catabolism

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Definition of deh

• Curated sequence F8SVK1: Acetate/haloacid transporter, Dehp2, with a possible atypical topology
• Curated sequence Q7X4L6: The acetate/monochloroacetate (haloacid) permease, Deh4p (Km = 5.5 mμM for acetate; 9 mμM for monochloroacetate)
• Curated sequence M1Q159: Acetate/monochloroacetate permease, Deh4p, of 468 aas and 12 TMSs
• Comment: Added the singleton Deh4p (M1Q159) from Dehalococcoides mccartyi, which has the same domain

Fetched 3 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 2 of these sequences

Found 1 clusters of similar sequences. Another 1 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 552-552 amino acids (not heteromeric)

TC 2.A.1.6.11 / F8SVK1 Acetate/haloacid transporter, Dehp2, with a possible atypical topology from Burkholderia sp. MBA4
PFams: Sugar_tr, MFS_1, Sugar_tr
552 amino acids: PaperBLAST, CDD, Compare to cluster

TC 2.A.1.6.8 / Q7X4L6 The acetate/monochloroacetate (haloacid) permease, Deh4p (Km = 5.5 mμM for acetate; 9 mμM for monochloroacetate) from Burkholderia cepacia
PFams: Sugar_tr, MFS_1, Sugar_tr
552 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/1 heteromeric)

TC 2.A.1.6.13 / M1Q159 Acetate/monochloroacetate permease, Deh4p, of 468 aas and 12 TMSs from Dehalococcoides mccartyi DCMB5
PFams: Sugar_tr, MFS_1
468 amino acids: PaperBLAST, CDD