Clusters of Characterized Proteins

GapMind for Amino acid biosynthesis

Clusters of Characterized Proteins

Clustering the characterized proteins for argH (argininosuccinate lyase) in L-arginine biosynthesis

Or see other characterized proteins similar to argH

Or see all steps for L-arginine biosynthesis

Or cluster curated proteins matching a keyword

Definition of argH

Curated proteins or TIGRFams with EC 4.3.2.1
Curated proteins matching argininosuccinate lyase
Curated proteins matching arginosuccinate lyase
Ignore hits to items matching Delta crystallin when looking for 'other' hits
Comment: Some ArgH proteins also funciton as Delta crystallin I, so ignore any similarity to those (even proteins not so annotated may be bifuncational).

Fetched 18 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 18 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 433-491 amino acids (not heteromeric)

The first sequence in each cluster is the seed.

Q8DVX5 argininosuccinate lyase (EC 4.3.2.1) from Streptococcus mutans
PFams: Lyase_1, ASL_C2
460 amino acids: PaperBLAST, CDD, Compare to cluster

P9WPY7 argininosuccinate lyase (EC 4.3.2.1) from Mycobacterium tuberculosis
PFams: Lyase_1, ASL_C2
470 amino acids: PaperBLAST, CDD, Compare to cluster

Q9P870 argininosuccinate lyase (EC 4.3.2.1) from Agaricus bisporus
PFams: Lyase_1, ASL_C2
463 amino acids: PaperBLAST, CDD, Compare to cluster

CH_122486 arginosuccinate lyase (Eurofung) from Emericella nidulans
PFams: Lyase_1, ASL_C2
491 amino acids: PaperBLAST, CDD, Compare to cluster

CH_123215 argininosuccinate lyase from Candida albicans
PFams: Lyase_1, ASL_C2
468 amino acids: PaperBLAST, CDD, Compare to cluster

RF|NP_595129.1 argininosuccinate lyase; EC 4.3.2.1 from Schizosaccharomyces pombe
PFams: Lyase_1, ASL_C2
461 amino acids: PaperBLAST, CDD, Compare to cluster

ARLY_YEAST / P04076 Argininosuccinate lyase; ASAL; Arginosuccinase; EC 4.3.2.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: Lyase_1, ASL_C2
463 amino acids: PaperBLAST, CDD, Compare to cluster

P04424 argininosuccinate lyase (EC 4.3.2.1) from Homo sapiens
ARLY_HUMAN / P04424 Argininosuccinate lyase; ASAL; Arginosuccinase; EC 4.3.2.1 from Homo sapiens (Human)
PFams: Lyase_1, ASL_C2
464 amino acids: PaperBLAST, CDD, Compare to cluster

ARLY2_ANAPL / P24058 Argininosuccinate lyase; ASAL; Arginosuccinase; Delta crystallin II; Delta-2 crystallin; EC 4.3.2.1 from Anas platyrhynchos (Mallard) (Anas boschas)
PFams: Lyase_1, ASL_C2
468 amino acids: PaperBLAST, CDD, Compare to cluster

ARLY_ANSAN / P33110 Argininosuccinate lyase; ASAL; Arginosuccinase; Delta crystallin; EC 4.3.2.1 from Anser anser anser (Western greylag goose)
PFams: Lyase_1, ASL_C2
466 amino acids: PaperBLAST, CDD, Compare to cluster

ARLY_COLLI / Q01592 Argininosuccinate lyase; ASAL; Arginosuccinase; Delta crystallin; EC 4.3.2.1 from Columba livia (Rock dove)
PFams: Lyase_1, ASL_C2
466 amino acids: PaperBLAST, CDD, Compare to cluster

ARLY_MOUSE / Q91YI0 Argininosuccinate lyase; ASAL; Arginosuccinase; EC 4.3.2.1 from Mus musculus (Mouse)
PFams: Lyase_1, ASL_C2
464 amino acids: PaperBLAST, CDD, Compare to cluster

ARLY_NOSP7 / Q9LAE5 Argininosuccinate lyase; ASAL; ASL; Arginosuccinase; EC 4.3.2.1 from Nostoc punctiforme (strain ATCC 29133 / PCC 73102)
Q9LAE5 argininosuccinate lyase (EC 4.3.2.1) from Nostoc sp.
PFams: Lyase_1, ASL_C2
461 amino acids: PaperBLAST, CDD, Compare to cluster

b3960 argininosuccinate lyase (EC 4.3.2.1) from Escherichia coli K-12 substr. MG1655
P11447 argininosuccinate lyase (EC 4.3.2.1) from Escherichia coli (strain K12)
PFams: Lyase_1, ASL_C2
457 amino acids: PaperBLAST, CDD, Compare to cluster

BT3733 arginosuccinate lyase (EC 4.3.2.1) from Bacteroides thetaiotaomicron VPI-5482
PFams: Lyase_1
446 amino acids: PaperBLAST, CDD, Compare to cluster

Echvi_3852 arginosuccinate lyase (EC 4.3.2.1) from Echinicola vietnamensis KMM 6221, DSM 17526
PFams: Lyase_1
444 amino acids: PaperBLAST, CDD, Compare to cluster

N515DRAFT_3770 arginosuccinate lyase (EC 4.3.2.1) from Dyella japonica UNC79MFTsu3.2
PFams: Lyase_1
433 amino acids: PaperBLAST, CDD, Compare to cluster

CA265_RS18485 arginosuccinate lyase (EC 4.3.2.1) from Pedobacter sp. GW460-11-11-14-LB5
PFams: Lyase_1
443 amino acids: PaperBLAST, CDD, Compare to cluster