Clusters of Characterized Proteins

GapMind for Amino acid biosynthesis

Clusters of Characterized Proteins

Clustering the characterized proteins for argI (ornithine carbamoyltransferase) in L-arginine biosynthesis

Or see other characterized proteins similar to argI

Or see all steps for L-arginine biosynthesis

Or cluster curated proteins matching a keyword

Definition of argI

Curated proteins or TIGRFams with EC 2.1.3.3
Ignore hits to items matching EC 2.1.3.6 when looking for 'other' hits
Comment: ArgI converts ornithine to citrulline. (E. coli has two paralogs, argI and argF.) Some putrescine carbamoyltransferases (EC 2.1.3.6) are also active on ornithine (Q837U7) so any similarity to those is ignored.

Fetched 32 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 32 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 295-375 amino acids (not heteromeric)

The first sequence in each cluster is the seed.

O93656 ornithine carbamoyltransferase (EC 2.1.3.3) from Pyrococcus abyssi
PFams: OTCace_N, OTCace
317 amino acids: PaperBLAST, CDD, Compare to cluster

P00480 Ornithine carbamoyltransferase, mitochondrial (EC 2.1.3.3) from Homo sapiens
OTC_HUMAN / P00480 Ornithine transcarbamylase, mitochondrial; OTCase; Ornithine carbamoyltransferase, mitochondrial; EC 2.1.3.3 from Homo sapiens (Human)
P00480 ornithine carbamoyltransferase (EC 2.1.3.3) from Homo sapiens
PFams: OTCace_N, OTCace
354 amino acids: PaperBLAST, CDD, Compare to cluster

OTC_MYCBO / P0A5M9 Ornithine carbamoyltransferase; OTCase; EC 2.1.3.3 from Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97)
OTC_MYCTU / P9WIT9 Ornithine carbamoyltransferase; OTCase; EC 2.1.3.3 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
P0A5M9 ornithine carbamoyltransferase (EC 2.1.3.3) from Mycobacterium tuberculosis variant bovis
P9WIT9 ornithine carbamoyltransferase (EC 2.1.3.3) from Mycobacterium tuberculosis
PFams: OTCace_N, OTCace
307 amino acids: PaperBLAST, CDD, Compare to cluster

OTC2A_PSESH / P68747 Ornithine carbamoyltransferase 2, anabolic; OTCase 2; Ornithine carbamoyltransferase 2, phaseolotoxin-insensitive; Phaseolotoxin-resistant ornithine carbamoyltransferase; Toxin-resistant enzyme; ROCT; EC 2.1.3.3 from Pseudomonas savastanoi pv. phaseolicola (Pseudomonas syringae pv. phaseolicola)
P68747 ornithine carbamoyltransferase (EC 2.1.3.3) from Pseudomonas savastanoi pv. phaseolicola
PFams: OTCace_N, OTCace
327 amino acids: PaperBLAST, CDD, Compare to cluster

Q48296 ArcB (EC 2.1.3.3) from Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1)
OTCC_HALSA / Q48296 Ornithine carbamoyltransferase, catabolic; cOTCase; EC 2.1.3.3 from Halobacterium salinarum (strain ATCC 700922 / JCM 11081 / NRC-1) (Halobacterium halobium)
Q48296 ornithine carbamoyltransferase (EC 2.1.3.3) from Halobacterium salinarum
PFams: OTCace_N, OTCace
295 amino acids: PaperBLAST, CDD, Compare to cluster

OTCA_PYRFU / Q51742 Ornithine carbamoyltransferase, anabolic; OTCase; EC 2.1.3.3 from Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Q51742 ornithine carbamoyltransferase (EC 2.1.3.3) from Pyrococcus furiosus
PFams: OTCace_N, OTCace
315 amino acids: PaperBLAST, CDD, Compare to cluster

Q5SJ15 ornithine carbamoyltransferase (EC 2.1.3.3) from Thermus thermophilus
PFams: OTCace_N, OTCace
301 amino acids: PaperBLAST, CDD, Compare to cluster

PTC_ENTFA / Q837U7 Putrescine carbamoyltransferase; PTC; PTCase; Agmatine catabolism protein B; Putrescine transcarbamoylase; Putrescine transcarbamylase; EC 2.1.3.6 from Enterococcus faecalis (strain ATCC 700802 / V583)
Q837U7 ornithine carbamoyltransferase (EC 2.1.3.3); putrescine carbamoyltransferase (EC 2.1.3.6) from Enterococcus faecalis
PFams: OTCace_N, OTCace
339 amino acids: PaperBLAST, CDD, Compare to cluster

Q98BB6 ornithine carbamoyltransferase (EC 2.1.3.3) from Mesorhizobium loti
PFams: OTCace_N, OTCace
303 amino acids: PaperBLAST, CDD, Compare to cluster

Q9PNU6 ornithine carbamoyltransferase (EC 2.1.3.3) from Campylobacter jejuni
PFams: OTCace_N, OTCace
306 amino acids: PaperBLAST, CDD, Compare to cluster

b4254 ornithine carbamoyltransferase ArgI (EC 2.1.3.3) from Escherichia coli K-12 substr. MG1655
P04391 ornithine carbamoyltransferase ArgI (EC 2.1.3.3) from Escherichia coli (strain K12)
OTC1_ECOLI / P04391 Ornithine carbamoyltransferase subunit I; OTCase-1; EC 2.1.3.3 from Escherichia coli (strain K12)
GB|AAA23483.1 ornithine carbamoyltransferase, subunit I; EC 2.1.3.3 from Escherichia coli K12
PFams: OTCace_N, OTCace
334 amino acids: PaperBLAST, CDD, Compare to cluster

GI|168017 ornithine carbamoyltransferase, mitochondrial; EC 2.1.3.3 from Emericella nidulans
PFams: OTCace_N, OTCace
359 amino acids: PaperBLAST, CDD, Compare to cluster

OTC_SCHPO / P31317 Ornithine carbamoyltransferase, mitochondrial; Ornithine transcarbamylase; OTCase; EC 2.1.3.3 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
GI|1204211 ornithine carbamoyltransferase Arg3; EC 2.1.3.3 from Schizosaccharomyces pombe
PFams: OTCace_N, OTCace
327 amino acids: PaperBLAST, CDD, Compare to cluster

OTC_MYCS2 / A0QYS8 Ornithine carbamoyltransferase; OTCase; EC 2.1.3.3 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
PFams: OTCace_N, OTCace
307 amino acids: PaperBLAST, CDD, Compare to cluster

OTC_RAT / P00481 Ornithine transcarbamylase, mitochondrial; OTCase; Ornithine carbamoyltransferase, mitochondrial; EC 2.1.3.3 from Rattus norvegicus (Rat)
PFams: OTCace_N, OTCace
354 amino acids: PaperBLAST, CDD, Compare to cluster

P05150 ornithine carbamoyltransferase (EC 2.1.3.3) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
OTC_YEAST / P05150 Ornithine carbamoyltransferase; Ornithine transcarbamylase; OTCase; EC 2.1.3.3 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: OTCace_N, OTCace
338 amino acids: PaperBLAST, CDD, Compare to cluster

b0273 CP4-6 prophage; ornithine carbamoyltransferase ArgF (EC 2.1.3.3) from Escherichia coli K-12 substr. MG1655
P06960 CP4-6 prophage; ornithine carbamoyltransferase ArgF (EC 2.1.3.3) from Escherichia coli (strain K12)
OTC2_ECOLI / P06960 Ornithine carbamoyltransferase subunit F; OTCase-2; EC 2.1.3.3 from Escherichia coli (strain K12)
PFams: OTCace_N, OTCace
334 amino acids: PaperBLAST, CDD, Compare to cluster

OTCC_PSEAE / P08308 Ornithine carbamoyltransferase, catabolic; OTCase; EC 2.1.3.3 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
PFams: OTCace_N, OTCace
336 amino acids: PaperBLAST, CDD, Compare to cluster

OTCA_PSEAE / P11724 Ornithine carbamoyltransferase, anabolic; OTCase; EC 2.1.3.3 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
PFams: OTCace_N, OTCace
305 amino acids: PaperBLAST, CDD, Compare to cluster

OTC_MOUSE / P11725 Ornithine transcarbamylase, mitochondrial; OTCase; Ornithine carbamoyltransferase, mitochondrial; EC 2.1.3.3 from Mus musculus (Mouse)
PFams: OTCace_N, OTCace
354 amino acids: PaperBLAST, CDD, Compare to cluster

OTC_SHEEP / P84010 Ornithine transcarbamylase, mitochondrial; OTCase; Ornithine carbamoyltransferase, mitochondrial; EC 2.1.3.3 from Ovis aries (Sheep)
PFams: OTCace_N, OTCace
355 amino acids: PaperBLAST, CDD, Compare to cluster

OTC_THET2 / P96134 Ornithine carbamoyltransferase; OTC; OTCase; EC 2.1.3.3 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27)
PFams: OTCace_N, OTCace
301 amino acids: PaperBLAST, CDD, Compare to cluster

OTC1A_PSESH / Q02047 Ornithine carbamoyltransferase 1, anabolic; OTCase 1; Ornithine carbamoyltransferase 1, phaseolotoxin-sensitive; SOCT; EC 2.1.3.3 from Pseudomonas savastanoi pv. phaseolicola (Pseudomonas syringae pv. phaseolicola)
PFams: OTCace_N, OTCace
306 amino acids: PaperBLAST, CDD, Compare to cluster

OTCC_MALP2 / Q8EVF5 Ornithine carbamoyltransferase, catabolic; OTCase; EC 2.1.3.3 from Malacoplasma penetrans (strain HF-2) (Mycoplasma penetrans)
PFams: OTCace_N, OTCace
342 amino acids: PaperBLAST, CDD, Compare to cluster

OTCC_LENHI / Q8G998 Ornithine carbamoyltransferase, catabolic; OTCase; EC 2.1.3.3 from Lentilactobacillus hilgardii (Lactobacillus hilgardii)
PFams: OTCace_N, OTCace
343 amino acids: PaperBLAST, CDD, Compare to cluster

OTC_MORAB / Q9K4Y9 Ornithine carbamoyltransferase; OTCase; EC 2.1.3.3 from Moritella abyssi
PFams: OTCace_N, OTCace
301 amino acids: PaperBLAST, CDD, Compare to cluster

OTC_CHICK / Q9YHY9 Ornithine transcarbamylase, mitochondrial; OTCase; Ornithine carbamoyltransferase, mitochondrial; EC 2.1.3.3 from Gallus gallus (Chicken)
PFams: OTCace_N, OTCace
354 amino acids: PaperBLAST, CDD, Compare to cluster

P18186 ArgF (EC 2.1.3.3) from Bacillus subtilis (strain 168)
PFams: OTCace_N, OTCace
319 amino acids: PaperBLAST, CDD, Compare to cluster

O50039 ornithine carbamoyltransferase (EC 2.1.3.3) from Arabidopsis thaliana
PFams: OTCace_N, OTCace
375 amino acids: PaperBLAST, CDD, Compare to cluster

P75473 ornithine carbamoyltransferase, catabolic (EC 2.1.3.3) from Mycoplasma pneumoniae (strain ATCC 29342 / M129 / Subtype 1)
PFams: OTCace_N, OTCace
346 amino acids: PaperBLAST, CDD, Compare to cluster

E3PX87 ornithine carbamoyltransferase (EC 2.1.3.3) from Acetoanaerobium sticklandii (strain ATCC 12662 / DSM 519 / JCM 1433 / CCUG 9281 / NCIMB 10654 / HF)
PFams: OTCace_N, OTCace
332 amino acids: PaperBLAST, CDD, Compare to cluster

HSERO_RS07185 Ornithine carbamoyltransferase (EC 2.1.3.3) from Herbaspirillum seropedicae SmR1
PFams: OTCace_N, OTCace
304 amino acids: PaperBLAST, CDD, Compare to cluster