Clusters of Characterized Proteins

GapMind for catabolism of small carbon sources

Clusters of Characterized Proteins

Clustering the characterized proteins for artP (L-arginine ABC transporter, ATPase component ArtP/HisP/AotP/BgtA) in L-arginine catabolism

Or see other characterized proteins similar to artP

Or see all steps for L-arginine catabolism

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Definition of artP

Curated sequence CH_003210: histidine transport ATP-binding protein hisP. Histidine transport ATP-binding protein HisP, component of Histidine/Arginine/Lysine (basic amino acid) uptake porter, HisJ/ArgT/HisP/HisM/HisQ [R, R, C, M, M, respectively] (Gilson et al. 1982). HisJ binds L-His (preferred), but 1-methyl-L-His and 3-methyl-L-His also bind, while the dipeptide carnosine binds weakly; D-histidine and the histidine degradation products, histamine, urocanic acid and imidazole do not bind. L-Arg, homo-L-Arg, and post-translationally modified methylated Arg-analogs also bind with the exception of symmetric dimethylated-L-Arg. L-Lys and L-Orn show weaker interactions with HisJ and methylated and acetylated Lys variants show poor binding.The carboxylate groups of these amino acids and their variants are essential. lysine/arginine/ornithine ABC transporter / histidine ABC transporter, ATP binding subunit (EC 7.4.2.1)
Curated sequence P02915: Histidine transport ATP-binding protein HisP. histidine transport atp-binding protein hisp. HisP aka STM2351, component of Histidine/arginine/lysine/ornithine porter (Heuveling et al. 2014). In contrast to some homologous homodimeric systems, the heterodimeric histidine transporter of Salmonella enterica Typhimurium
Curated sequence P0AAF6: Arginine transport ATP-binding protein ArtP; EC 7.4.2.-. Arginine transport ATP-binding protein ArtP aka B0864, component of Arginine porter. L-arginine ABC transporter ATP binding subunit (EC 7.4.2.1). L-arginine ABC transporter ATP binding subunit (EC 7.4.2.1)
Curated sequence P54537: Arginine transport ATP-binding protein ArtM
Curated sequence O30506: AotP aka PA0892, component of Arginine/ornithine (but not lysine) porter
Curated sequence P73721: BgtA aka SLR1735, component of Arginine/lysine/histidine/glutamine porter
Curated sequence Q9HU32: Probable ATP-binding component of ABC transporter, component of Amino acid transporter, PA5152-PA5155. Probably transports numerous amino acids including lysine, arginine, histidine, D-alanine and D-valine (Johnson et al. 2008). Regulated by ArgR
Curated sequence BPHYT_RS07685: ABC transporter for L-Arginine, putative ATPase component
Curated sequence Pf1N1B4_3435: ABC transporter for L-Arginine and L-Citrulline, ATPase component
Curated sequence AO353_03040: ABC transporter for L-Arginine and L-Citrulline, ATPase component
Curated sequence AO356_18715: L-Arginine ABC transporter, ATPase component
Curated sequence Pf6N2E2_5663: L-Arginine ABC transporter, ATPase component
Ignore hits to AO356_09895 when looking for 'other' hits (ABC transporter for L-Lysine, ATPase component)
Ignore hits to AO356_05515 when looking for 'other' hits (ABC transporter for L-Lysine, ATPase component)
Ignore hits to Pf6N2E2_2962 when looking for 'other' hits (ABC transporter for L-Lysine, ATPase component)
Comment: Ignore closely related lysine transporters from P. fluorescens (which may well transport arginine; AO356_09895 has a subtle defect in arginine utilization)

Fetched 12 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 12 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 240-263 amino acids (11/12 heteromeric)

The first sequence in each cluster is the seed.

b2306 lysine/arginine/ornithine ABC transporter / histidine ABC transporter, ATP binding subunit (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655
TC 3.A.1.3.29 / P07109 Histidine transport ATP-binding protein HisP, component of Histidine/Arginine/Lysine (basic amino acid) uptake porter, HisJ/ArgT/HisP/HisM/HisQ [R, R, C, M, M, respectively] (Gilson et al. 1982). HisJ binds L-His (preferred), but 1-methyl-L-His and 3-methyl-L-His also bind, while the dipeptide carnosine binds weakly; D-histidine and the histidine degradation products, histamine, urocanic acid and imidazole do not bind. L-Arg, homo-L-Arg, and post-translationally modified methylated Arg-analogs also bind with the exception of symmetric dimethylated-L-Arg. L-Lys and L-Orn show weaker interactions with HisJ and methylated and acetylated Lys variants show poor binding.The carboxylate groups of these amino acids and their variants are essential from Escherichia coli (strain K12)
GB|AAC75366.1 histidine transport ATP-binding protein hisP from Escherichia coli K12
PFams: ABC_tran, AAA_21
Heteromeric, 257 amino acids: PaperBLAST, CDD, Compare to cluster

HISP_SALTY / P02915 Histidine transport ATP-binding protein HisP from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
TC 3.A.1.3.1 / P02915 HisP aka STM2351, component of Histidine/arginine/lysine/ornithine porter (Heuveling et al. 2014). In contrast to some homologous homodimeric systems, the heterodimeric histidine transporter of Salmonella enterica Typhimurium from Salmonella typhimurium
RF|NP_461293.1 histidine transport atp-binding protein hisp from Salmonella enterica subsp. enterica serovar Typhimurium
PFams: ABC_tran, AAA_21
Heteromeric, 258 amino acids: PaperBLAST, CDD, Compare to cluster

b0864 L-arginine ABC transporter ATP binding subunit (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655
P0AAF6 L-arginine ABC transporter ATP binding subunit (EC 7.4.2.1) from Escherichia coli (strain K12)
ARTP_ECOLI / P0AAF6 Arginine transport ATP-binding protein ArtP; EC 7.4.2.- from Escherichia coli (strain K12)
TC 3.A.1.3.3 / P0AAF6 Arginine transport ATP-binding protein ArtP aka B0864, component of Arginine porter from Escherichia coli
PFams: ABC_tran, AAA_21
Heteromeric, 242 amino acids: PaperBLAST, CDD, Compare to cluster

ARTM_BACSU / P54537 Arginine transport ATP-binding protein ArtM from Bacillus subtilis (strain 168)
PFams: ABC_tran, AAA_21
240 amino acids: PaperBLAST, CDD, Compare to cluster

TC 3.A.1.3.11 / O30506 AotP aka PA0892, component of Arginine/ornithine (but not lysine) porter from Pseudomonas aeruginosa
PFams: ABC_tran, AAA_21
Heteromeric, 254 amino acids: PaperBLAST, CDD, Compare to cluster

TC 3.A.1.3.12 / P73721 BgtA aka SLR1735, component of Arginine/lysine/histidine/glutamine porter
PFams: ABC_tran
Heteromeric, 252 amino acids: PaperBLAST, CDD, Compare to cluster

TC 3.A.1.3.23 / Q9HU32 Probable ATP-binding component of ABC transporter, component of Amino acid transporter, PA5152-PA5155. Probably transports numerous amino acids including lysine, arginine, histidine, D-alanine and D-valine (Johnson et al. 2008). Regulated by ArgR from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
PFams: ABC_tran, AAA_21
Heteromeric, 257 amino acids: PaperBLAST, CDD, Compare to cluster

BPHYT_RS07685 ABC transporter for L-Arginine, putative ATPase component from Burkholderia phytofirmans PsJN
PFams: ABC_tran, AAA_21
Heteromeric, 263 amino acids: PaperBLAST, CDD, Compare to cluster

Pf1N1B4_3435 ABC transporter for L-Arginine and L-Citrulline, ATPase component from Pseudomonas fluorescens FW300-N1B4
PFams: ABC_tran, AAA_21
Heteromeric, 254 amino acids: PaperBLAST, CDD, Compare to cluster

AO353_03040 ABC transporter for L-Arginine and L-Citrulline, ATPase component from Pseudomonas fluorescens FW300-N2E3
PFams: ABC_tran, AAA_21
Heteromeric, 254 amino acids: PaperBLAST, CDD, Compare to cluster

AO356_18715 L-Arginine ABC transporter, ATPase component from Pseudomonas fluorescens FW300-N2C3
PFams: ABC_tran
Heteromeric, 254 amino acids: PaperBLAST, CDD, Compare to cluster

Pf6N2E2_5663 L-Arginine ABC transporter, ATPase component from Pseudomonas fluorescens FW300-N2E2
PFams: ABC_tran
Heteromeric, 254 amino acids: PaperBLAST, CDD, Compare to cluster