Clusters of Characterized Proteins

GapMind for catabolism of small carbon sources

Clusters of Characterized Proteins

Clustering the characterized proteins for puuC (gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase) in L-arginine catabolism

Or see other characterized proteins similar to puuC

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Or cluster curated proteins matching a keyword

Definition of puuC

Curated proteins or TIGRFams with EC 1.2.1.99
Curated sequence MONOMER-11560: 4-guanidinobutyraldehyde dehydrogenase (EC 1.2.1.54)
Curated sequence PfGW456L13_805: gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase (EC 1.2.1.54)
Curated sequence Pf6N2E2_4383: gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase (EC 1.2.1.54)
Curated sequence AO356_12580: gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase (EC 1.2.1.54)
Curated sequence GFF5420: gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase (EC 1.2.1.54)
Comment: The putative kauB (4-guanidinobutyraldehyde dehydrogenase) from P. putida (metacyc::MONOMER-11560) is included because it is closely related to P. aeruginosa kauB (PA5312), which acts on gamma-glutamyl-gamma-aminobutyraldehyde as well (PMID:3141581). Some other P. fluorescens kauB-type proteins seem to be acting in this pathway but were annotated with EC 1.2.1.54 instead, so these were added manually.

Fetched 6 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 6 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 495-497 amino acids (not heteromeric)

The first sequence in each cluster is the seed.

b1300 γ-glutamyl-γ-aminobutyraldehyde dehydrogenase (EC 1.2.1.19; EC 1.2.1.24; EC 1.2.1.99) from Escherichia coli K-12 substr. MG1655
P23883 γ-glutamyl-γ-aminobutyraldehyde dehydrogenase (EC 1.2.1.19; EC 1.2.1.24; EC 1.2.1.99) from Escherichia coli (strain K12)
PUUC_ECOLI / P23883 NADP/NAD-dependent aldehyde dehydrogenase PuuC; ALDH; 3-hydroxypropionaldehyde dehydrogenase; Gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase; Gamma-Glu-gamma-aminobutyraldehyde dehydrogenase; EC 1.2.1.5 from Escherichia coli (strain K12)
P23883 4-(gamma-glutamylamino)butanal dehydrogenase (EC 1.2.1.99) from Escherichia coli
PFams: Aldedh
495 amino acids: PaperBLAST, CDD, Compare to cluster

Q88CA3 4-guanidinobutyraldehyde dehydrogenase (EC 1.2.1.54) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
PFams: Aldedh
497 amino acids: PaperBLAST, CDD, Compare to cluster

PS417_27745 gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase (EC 1.2.1.54) from Pseudomonas simiae WCS417
PFams: Aldedh
497 amino acids: PaperBLAST, CDD, Compare to cluster

PfGW456L13_805 gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase (EC 1.2.1.54) from Pseudomonas fluorescens GW456-L13
PFams: Aldedh
497 amino acids: PaperBLAST, CDD, Compare to cluster

AO356_12580 gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase (EC 1.2.1.54) from Pseudomonas fluorescens FW300-N2C3
PFams: Aldedh
497 amino acids: PaperBLAST, CDD, Compare to cluster

Pf6N2E2_4383 gamma-glutamyl-gamma-aminobutyraldehyde dehydrogenase (EC 1.2.1.54) from Pseudomonas fluorescens FW300-N2E2
PFams: Aldedh
497 amino acids: PaperBLAST, CDD, Compare to cluster