Clusters of Characterized Proteins

Clustering the characterized proteins for natF (aspartate ABC transporter, substrate-binding component NatF) in L-asparagine catabolism

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Definition of natF

• Curated sequence Q8YPM9: NatF, component of Acidic and neutral amino acid uptake transporter NatFGH/BgtA. BgtA is shared with BgtAB
• UniProt sequence Q31RP1: SubName: Full=Extracellular solute-binding protein, family 3 {ECO:0000313|EMBL:ABB56278.1};
• Comment: dmeA is described in TCDB as an aspartate transporter, but the cited paper (PMC:PMC4507348) instead suggests that Synpcc7942_0246 to Synpcc7942_0249 is an ABC transporter for aspartate and glutamate. 3/4 subunits are closely related to those of Anabaena N-II (NatFGH-BgtA), which is the main aspartate transporter (PMID:18208492). (For N-II, TC 3.A.1.3.18 lists 3 components NatFGH). Of Synpcc7942_0246 to Synpcc7942_0249: _0246 = Q31RP1 is similar to NatF, _0247 = Q31RP0 is a permease component and is usually named BgtB (but is *not* closely related to Anabaena BgtB), _0248 = Q31RN9 is NatH-like, and _0249 = Q31RN8 is BgtA-like. Anabaena bgtB = alr3187 is not closely related to _0247.

Fetched 2 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 2 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 359-369 amino acids (1/2 heteromeric)

TC 3.A.1.3.18 / Q8YPM9 NatF, component of Acidic and neutral amino acid uptake transporter NatFGH/BgtA. BgtA is shared with BgtAB
PFams: SBP_bac_3, NMT1
Heteromeric, 369 amino acids: PaperBLAST, CDD, Compare to cluster

Q31RP1 Extracellular solute-binding protein, family 3
359 amino acids: PaperBLAST, CDD, Compare to cluster