Clusters of Characterized Proteins

GapMind for catabolism of small carbon sources

Clusters of Characterized Proteins

Clustering the characterized proteins for bglG (cellobiose PTS system, EII-BC or EII-BCA components) in D-cellobiose catabolism

Or see other characterized proteins similar to bglG

Or see all steps for D-cellobiose catabolism

Or cluster curated proteins matching a keyword

Definition of bglG

Curated sequence P24241: PTS system arbutin-, cellobiose-, and salicin-specific EIIBC component; EIIBC-Asc; EII-Asc; EC 2.7.1.-. β-Glucoside [arbutin-salicin-cellobiose] (ASC) group translocator, AscF. β-glucoside specific PTS enzyme IIBC component (EC 2.7.1.199). β-glucoside specific PTS enzyme IIBC component (EC 2.7.1.199)
Curated sequence ART98499: PTS beta-glucoside transporter, EIIBCA of 672 aas and 12 predicted TMSs
Curated sequence P08722: β-Glucoside (salicin, arbutin, cellobiose, etc) group translocator, BglF. β-glucoside specific PTS enzyme II / BglG kinase / BglG phosphatase (EC 2.7.1.199). β-glucoside specific PTS enzyme II / BglG kinase / BglG phosphatase (EC 2.7.1.199)
Curated sequence Q8GGK3: β-glucoside (methyl-β-glucoside, salicin, arbutin) porter, BglF [a V317A or V317M mutation allows it to transport cellobiose as well]
Comment: Lactobacillus gasseri has EII-BCA, and E. coli has EII-BCA (bglG). E. coli also has a similar system, EII-BC (ascF); the EII-A component is not known. A single-a.a. mutation to a EII-BCA from Corynebacterium glutamicum (TC 4.A.1.2.5 / Q8GGK3) allows it to transport cellobiose, so that is included as well.

Fetched 4 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 4 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 485-672 amino acids (not heteromeric)

The first sequence in each cluster is the seed.

TC 4.A.1.2.14 / ART98499 PTS beta-glucoside transporter, EIIBCA of 672 aas and 12 predicted TMSs from Lactobacillus gasseri
PFams: PTS_EIIB, PTS_EIIC, PTS_EIIA_1
672 amino acids: PaperBLAST, CDD, Compare to cluster

b2715 β-glucoside specific PTS enzyme IIBC component (EC 2.7.1.199) from Escherichia coli K-12 substr. MG1655
P24241 β-glucoside specific PTS enzyme IIBC component (EC 2.7.1.199) from Escherichia coli (strain K12)
PTIBC_ECOLI / P24241 PTS system arbutin-, cellobiose-, and salicin-specific EIIBC component; EIIBC-Asc; EII-Asc; EC 2.7.1.- from Escherichia coli (strain K12)
TC 4.A.1.2.3 / P24241 β-Glucoside [arbutin-salicin-cellobiose] (ASC) group translocator, AscF
PFams: PTS_EIIB, PTS_EIIC
485 amino acids: PaperBLAST, CDD, Compare to cluster

b3722 β-glucoside specific PTS enzyme II / BglG kinase / BglG phosphatase (EC 2.7.1.199) from Escherichia coli K-12 substr. MG1655
P08722 β-glucoside specific PTS enzyme II / BglG kinase / BglG phosphatase (EC 2.7.1.199) from Escherichia coli (strain K12)
TC 4.A.1.2.2 / P08722 β-Glucoside (salicin, arbutin, cellobiose, etc) group translocator, BglF from Escherichia coli
PFams: PTS_EIIB, PTS_EIIC, PTS_EIIA_1
625 amino acids: PaperBLAST, CDD, Compare to cluster

TC 4.A.1.2.5 / Q8GGK3 β-glucoside (methyl-β-glucoside, salicin, arbutin) porter, BglF [a V317A or V317M mutation allows it to transport cellobiose as well] from Corynebacterium glutamicum (Brevibacterium flavum)
PFams: PTS_EIIB, PTS_EIIC, PTS_EIIA_1
618 amino acids: PaperBLAST, CDD, Compare to cluster