Clusters of Characterized Proteins

GapMind for catabolism of small carbon sources

Clusters of Characterized Proteins

Clustering the characterized proteins for manY (glucose PTS, enzyme EIIC) in D-cellobiose catabolism

Or see other characterized proteins similar to manY

Or see all steps for D-cellobiose catabolism

Or cluster curated proteins matching a keyword

Definition of manY

Curated sequence CH_088330: mannose permease IIC component. PTS system mannose-specific EIIC component; EII-P-Man; EIIC-Man; Mannose permease IIC component. PTNC aka MANY aka PTSP aka PEL aka B1818, component of The mannose (glucose, 2-deoxyglucose, glucosamine, N-acetylglucosamine, N-acetylmannosamine, mannosamine and fructose) PTS porter/group translocator, ManXYZ (Rephaeli and Saier 1980; Plumbridge 2015). Catalyzes xylose facilitated diffusion in lactobacilli. The order of D-sugar substrate affinities is: glucose > mannose > 2-deoxyglucose > N-acetylglucosamine > glucosamine > N-acetylmannosamine > mannosamine > fructose. mannose-specific PTS enzyme IIC component (EC 2.7.1.191; EC 2.7.1.199; EC 2.7.1.193). mannose-specific PTS enzyme IIC component (EC 2.7.1.191; EC 2.7.1.199; EC 2.7.1.193)
Curated sequence E1UCI1: PTS system, mannose/fructose/sorbose family, IIC component, component of The primary glucose /mannose uptake transporter, ManLMN
Curated sequence Q04GK0: Mannose-specific PTS system component IIC, component of The hexose (glucose and fructose demonstrated) PTS uptake system
Curated sequence Q2QKM3: ManM aka EIIC, component of Glucose porter, ManLMN
Curated sequence Q5M5W7: ManM, component of The glucose/mannose/2-deoxyglucose/fructose phosphotransferase systems (phosphorylates without transport), ManLMN
Comment: Also similar is Lmo0782 (TC 4.A.6.1.16 / Q8Y8W0) from MpoABCD, a PTS-like glucose sensor; this is not ignored but possibly should be.

Fetched 5 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 5 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 266-275 amino acids (heteromeric)

The first sequence in each cluster is the seed.

b1818 mannose-specific PTS enzyme IIC component (EC 2.7.1.191; EC 2.7.1.199; EC 2.7.1.193) from Escherichia coli K-12 substr. MG1655
P69801 mannose-specific PTS enzyme IIC component (EC 2.7.1.191; EC 2.7.1.199; EC 2.7.1.193) from Escherichia coli (strain K12)
PTNC_ECOLI / P69801 PTS system mannose-specific EIIC component; EII-P-Man; EIIC-Man; Mannose permease IIC component from Escherichia coli (strain K12)
TC 4.A.6.1.1 / P69801 PTNC aka MANY aka PTSP aka PEL aka B1818, component of The mannose (glucose, 2-deoxyglucose, glucosamine, N-acetylglucosamine, N-acetylmannosamine, mannosamine and fructose) PTS porter/group translocator, ManXYZ (Rephaeli and Saier 1980; Plumbridge 2015). Catalyzes xylose facilitated diffusion in lactobacilli. The order of D-sugar substrate affinities is: glucose > mannose > 2-deoxyglucose > N-acetylglucosamine > glucosamine > N-acetylmannosamine > mannosamine > fructose from Escherichia coli
CH_088330 mannose permease IIC component from Escherichia coli K12
PFams: EII-Sor
Heteromeric, 266 amino acids: PaperBLAST, CDD, Compare to cluster

TC 4.A.6.1.15 / E1UCI1 PTS system, mannose/fructose/sorbose family, IIC component, component of The primary glucose /mannose uptake transporter, ManLMN from Listeria monocytogenes serotype 4a (strain L99)
PFams: EII-Sor
Heteromeric, 268 amino acids: PaperBLAST, CDD, Compare to cluster

TC 4.A.6.1.10 / Q04GK0 Mannose-specific PTS system component IIC, component of The hexose (glucose and fructose demonstrated) PTS uptake system from Oenococcus oeni (strain BAA-331 / PSU-1)
PFams: EII-Sor
Heteromeric, 271 amino acids: PaperBLAST, CDD, Compare to cluster

TC 4.A.6.1.6 / Q2QKM3 ManM aka EIIC, component of Glucose porter, ManLMN from Lactobacillus casei
PFams: EII-Sor
Heteromeric, 271 amino acids: PaperBLAST, CDD, Compare to cluster

TC 4.A.6.1.7 / Q5M5W7 ManM, component of The glucose/mannose/2-deoxyglucose/fructose phosphotransferase systems (phosphorylates without transport), ManLMN from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
PFams: EII-Sor
Heteromeric, 275 amino acids: PaperBLAST, CDD, Compare to cluster