GapMind for catabolism of small carbon sources

 

Clusters of Characterized Proteins

Clustering the characterized proteins for acn (aconitase) in citrate catabolism

Or see other characterized proteins similar to acn

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Or cluster curated proteins matching a keyword

Definition of acn

Fetched 52 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 52 of these sequences

Found 5 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 780-995 amino acids (not heteromeric)

Q4JFF1 phosphinomethylmalate isomerase (EC 4.2.1.166) (from HMM only) from Streptomyces viridochromogenes
PFams: Aconitase, Aconitase_C
889 amino acids: PaperBLAST, CDD, Compare to cluster

A0A090AMG4 aconitate hydratase (EC 4.2.1.3) from Achromobacter denitrificans
PFams: Aconitase, Aconitase_C
901 amino acids: PaperBLAST, CDD, Compare to cluster

D3GQL0 aconitate hydratase (EC 4.2.1.3) from Citrus clementina
PFams: Aconitase, Aconitase_C
900 amino acids: PaperBLAST, CDD, Compare to cluster

D3GQL1 aconitate hydratase (EC 4.2.1.3) from Citrus clementina
PFams: Aconitase, Aconitase_C
898 amino acids: PaperBLAST, CDD, Compare to cluster

D3GQL2 aconitate hydratase (EC 4.2.1.3) from Citrus clementina
PFams: Aconitase, Aconitase_C
898 amino acids: PaperBLAST, CDD, Compare to cluster

ACNA_BACSU / P09339 Aconitate/2-methylaconitate hydratase; Aconitate hydratase A; ACN; Aconitase; Iron-responsive protein-like; IRP-like; RNA-binding protein; EC 4.2.1.-; EC 4.2.1.3 from Bacillus subtilis (strain 168)
P09339 aconitate hydratase (EC 4.2.1.3) from Bacillus subtilis
PFams: Aconitase, Aconitase_C
909 amino acids: PaperBLAST, CDD, Compare to cluster

P21399 cytoplasmic aconitate hydratase from Homo sapiens
ACOC_HUMAN / P21399 Cytoplasmic aconitate hydratase; Aconitase; Citrate hydro-lyase; Ferritin repressor protein; Iron regulatory protein 1; IRP1; Iron-responsive element-binding protein 1; IRE-BP 1; EC 4.2.1.3 from Homo sapiens (Human)
P21399 aconitate hydratase (EC 4.2.1.3) from Homo sapiens
PFams: Aconitase, Aconitase_C
889 amino acids: PaperBLAST, CDD, Compare to cluster

b1276 aconitate hydratase 1 from Escherichia coli K-12 substr. MG1655
P25516 aconitate hydratase 1 from Escherichia coli (strain K12)
ACNA_ECOLI / P25516 Aconitate hydratase A; ACN; Aconitase; Iron-responsive protein-like; IRP-like; RNA-binding protein; Stationary phase enzyme; EC 4.2.1.3 from Escherichia coli (strain K12)
P25516 aconitate hydratase (EC 4.2.1.3) from Escherichia coli
CH_002745 aconitate hydratase 1; EC 4.2.1.3 from Escherichia coli K12
PFams: Aconitase, Aconitase_C
891 amino acids: PaperBLAST, CDD, Compare to cluster

P28271 aconitate hydratase (EC 4.2.1.3) from Mus musculus
PFams: Aconitase, Aconitase_C
889 amino acids: PaperBLAST, CDD, Compare to cluster

ACOC_CAEEL / Q23500 Probable cytoplasmic aconitate hydratase; Aconitase; Citrate hydro-lyase; Gex-3-interacting protein 22; EC 4.2.1.3 from Caenorhabditis elegans
Q23500 aconitate hydratase (EC 4.2.1.3) from Caenorhabditis elegans
PFams: Aconitase, Aconitase_C
887 amino acids: PaperBLAST, CDD, Compare to cluster

Q42560 aconitase from Arabidopsis thaliana
ACO1_ARATH / Q42560 Aconitate hydratase 1; Aconitase 1; Citrate hydro-lyase 1; EC 4.2.1.3 from Arabidopsis thaliana (Mouse-ear cress)
Q42560 aminocyclopropanecarboxylate oxidase (EC 1.14.17.4) from Arabidopsis thaliana
PFams: Aconitase, Aconitase_C
898 amino acids: PaperBLAST, CDD, Compare to cluster

Q63270 aconitate hydratase (EC 4.2.1.3) from Rattus norvegicus
PFams: Aconitase, Aconitase_C
889 amino acids: PaperBLAST, CDD, Compare to cluster

ACND_SHEON / Q8EJW3 2-methylcitrate dehydratase (2-methyl-trans-aconitate forming); Aconitate hydratase; ACN; Aconitase; EC 4.2.1.117; EC 4.2.1.3 from Shewanella oneidensis (strain MR-1)
Q8EJW3 2-methylcitrate dehydratase (2-methyl-trans-aconitate forming) (EC 4.2.1.117) from Shewanella oneidensis
PFams: Aconitase, Aconitase_C
867 amino acids: PaperBLAST, CDD, Compare to cluster

Q99KI0 aconitate hydratase (EC 4.2.1.3) from Mus musculus
PFams: Aconitase, Aconitase_C
780 amino acids: PaperBLAST, CDD, Compare to cluster

Q9NFX2 aconitate hydratase (EC 4.2.1.3) from Drosophila melanogaster
PFams: Aconitase, Aconitase_C
899 amino acids: PaperBLAST, CDD, Compare to cluster

Q9NFX3 aconitate hydratase (EC 4.2.1.3) from Drosophila melanogaster
PFams: Aconitase, Aconitase_C
902 amino acids: PaperBLAST, CDD, Compare to cluster

Q9RIL1 aconitate hydratase (EC 4.2.1.3) from Streptomyces viridochromogenes
PFams: Aconitase, Aconitase_C
931 amino acids: PaperBLAST, CDD, Compare to cluster

ACO3M_ARATH / Q9SIB9 Aconitate hydratase 3, mitochondrial; Aconitase 3; mACO1; Citrate hydro-lyase 3; EC 4.2.1.3 from Arabidopsis thaliana (Mouse-ear cress)
Q9SIB9 aconitate hydratase (EC 4.2.1.3) from Arabidopsis thaliana
PFams: Aconitase, Aconitase_C
990 amino acids: PaperBLAST, CDD, Compare to cluster

ACON_EMENI / C8VG90 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; Homocitrate dehydratase; EC 4.2.1.3; EC 4.2.1.- from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
PFams: Aconitase, Aconitase_C
783 amino acids: PaperBLAST, CDD, Compare to cluster

O53166 aconitase from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
ACNA_MYCTU / O53166 Aconitate hydratase A; ACN; Aconitase; (2R,3S)-2-methylisocitrate dehydratase; (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase; Iron-responsive protein-like; IRP-like; Probable 2-methyl-cis-aconitate hydratase; RNA-binding protein; EC 4.2.1.3; EC 4.2.1.99 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
PFams: Aconitase, Aconitase_C
943 amino acids: PaperBLAST, CDD, Compare to cluster

ACON_PIG / P16276 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Sus scrofa (Pig)
PFams: Aconitase, Aconitase_C
781 amino acids: PaperBLAST, CDD, Compare to cluster

ACON_LEGPH / P37032 Aconitate hydratase A; ACN; Aconitase; (2R,3S)-2-methylisocitrate dehydratase; (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase; IP210; Iron-responsive protein-like; IRP-like; Major iron-containing protein; MICP; Probable 2-methyl-cis-aconitate hydratase; RNA-binding protein; EC 4.2.1.3; EC 4.2.1.99 from Legionella pneumophila subsp. pneumophila (strain Philadelphia 1 / ATCC 33152 / DSM 7513)
PFams: Aconitase, Aconitase_C
891 amino acids: PaperBLAST, CDD, Compare to cluster

IREB2_HUMAN / P48200 Iron-responsive element-binding protein 2; IRE-BP 2; Iron regulatory protein 2; IRP2 (from HMM only) from Homo sapiens (Human)
PFams: Aconitase, Aconitase, Aconitase_C
963 amino acids: PaperBLAST, CDD, Compare to cluster

ACNA_BRADU / P70920 Aconitate hydratase A; ACN; Aconitase; (2R,3S)-2-methylisocitrate dehydratase; (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase; Iron-responsive protein-like; IRP-like; Probable 2-methyl-cis-aconitate hydratase; RNA-binding protein; EC 4.2.1.3; EC 4.2.1.99 from Bradyrhizobium diazoefficiens (strain JCM 10833 / IAM 13628 / NBRC 14792 / USDA 110)
PFams: Aconitase, Aconitase_C
906 amino acids: PaperBLAST, CDD, Compare to cluster

ACON_ASPFU / Q4WLN1 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; Homocitrate dehydratase; EC 4.2.1.3; EC 4.2.1.- from Neosartorya fumigata (strain ATCC MYA-4609 / Af293 / CBS 101355 / FGSC A1100) (Aspergillus fumigatus)
PFams: Aconitase, Aconitase_C
787 amino acids: PaperBLAST, CDD, Compare to cluster

ACNA_THET8 / Q5SMF6 Aconitate hydratase A; ACN; Aconitase; (2R,3S)-2-methylisocitrate dehydratase; (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase; Iron-responsive protein-like; IRP-like; Probable 2-methyl-cis-aconitate hydratase; RNA-binding protein; EC 4.2.1.3; EC 4.2.1.99 from Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
PFams: Aconitase, Aconitase_C
902 amino acids: PaperBLAST, CDD, Compare to cluster

IREB2_MOUSE / Q811J3 Iron-responsive element-binding protein 2; IRE-BP 2; Iron regulatory protein 2; IRP2 (from HMM only) from Mus musculus (Mouse)
PFams: Aconitase, Aconitase, Aconitase_C
963 amino acids: PaperBLAST, CDD, Compare to cluster

ACNA_CORGL / Q8NQ98 Aconitate hydratase A; ACN; Aconitase; (2R,3S)-2-methylisocitrate dehydratase; (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase; Iron-responsive protein-like; IRP-like; Probable 2-methyl-cis-aconitate hydratase; RNA-binding protein; EC 4.2.1.3; EC 4.2.1.99 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
PFams: Aconitase, Aconitase_C
939 amino acids: PaperBLAST, CDD, Compare to cluster

Q8ZP52 aconitate hydratase 1 (EC 4.2.1.99) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
ACNA_SALTY / Q8ZP52 Aconitate hydratase A; ACN; Aconitase; (2R,3S)-2-methylisocitrate dehydratase; (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase; 2-methyl-cis-aconitate hydratase; Iron-responsive protein-like; IRP-like; RNA-binding protein; EC 4.2.1.3; EC 4.2.1.99 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
PFams: Aconitase, Aconitase_C
891 amino acids: PaperBLAST, CDD, Compare to cluster

ACNA_CUPNE / Q937N8 Aconitate hydratase A; Aconitase; (2R,3S)-2-methylisocitrate dehydratase; (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase; Iron-responsive protein-like; IRP-like; Probable 2-methyl-cis-aconitate hydratase; RNA-binding protein; EC 4.2.1.3; EC 4.2.1.99 from Cupriavidus necator (Alcaligenes eutrophus) (Ralstonia eutropha)
PFams: Aconitase, Aconitase_C
869 amino acids: PaperBLAST, CDD, Compare to cluster

ACO2M_ARATH / Q94A28 Aconitate hydratase 2, mitochondrial; Aconitase 2; mACO2; Citrate hydro-lyase 2; EC 4.2.1.3 from Arabidopsis thaliana (Mouse-ear cress)
PFams: Aconitase, Aconitase_C
995 amino acids: PaperBLAST, CDD, Compare to cluster

A0A0M3N196 phosphinomethylmalate isomerase (EC 4.2.1.166) (from HMM only) from Kitasatospora phosalacinea
PFams: Aconitase, Aconitase_C
882 amino acids: PaperBLAST, CDD, Compare to cluster

HP15_3433 Aconitate hydratase (EC 4.2.1.3) from Marinobacter adhaerens HP15
PFams: Aconitase, Aconitase_C
919 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 747-918 amino acids (not heteromeric)

CH_122731 aconitate hydratase; EC 4.2.1.3 from Candida albicans
PFams: Aconitase, Aconitase_C
777 amino acids: PaperBLAST, CDD, Compare to cluster

ACON_YEAST / P19414 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
P19414 aconitate hydratase (EC 4.2.1.3) from Saccharomyces cerevisiae
PFams: Aconitase, Aconitase_C
778 amino acids: PaperBLAST, CDD, Compare to cluster

Q8RP87 aconitate hydratase (EC 4.2.1.3) from Bacteroides fragilis
PFams: Aconitase, Aconitase_C
747 amino acids: PaperBLAST, CDD, Compare to cluster

Q99798 mitochondrial aconitate hydratase from Homo sapiens
ACON_HUMAN / Q99798 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Homo sapiens (Human)
Q99798 aconitate hydratase (EC 4.2.1.3) from Homo sapiens
PFams: Aconitase, Aconitase_C
780 amino acids: PaperBLAST, CDD, Compare to cluster

Q9ER34 aconitate hydratase (EC 4.2.1.3) from Rattus norvegicus
PFams: Aconitase, Aconitase_C
780 amino acids: PaperBLAST, CDD, Compare to cluster

ACON2_SCHPO / Q9P7D4 Homocitrate dehydratase, mitochondrial; Aconitase 2; EC 4.2.1.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Q9P7D4 aconitate hydratase (EC 4.2.1.3) from Schizosaccharomyces pombe
PFams: Aconitase, Aconitase_C, Ribosomal_L21p
918 amino acids: PaperBLAST, CDD, Compare to cluster

ACON_SCHPO / O13966 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
PFams: Aconitase, Aconitase_C
789 amino acids: PaperBLAST, CDD, Compare to cluster

ACON_BOVIN / P20004 Aconitate hydratase, mitochondrial; Aconitase; Citrate hydro-lyase; EC 4.2.1.3 from Bos taurus (Bovine)
PFams: Aconitase, Aconitase_C
780 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 3 852-930 amino acids (not heteromeric)

A0A2X5AHR8 aconitate hydratase (EC 4.2.1.3) from Helicobacter pylori
PFams: Aconitase_B_N, Aconitase_2_N, Aconitase
852 amino acids: PaperBLAST, CDD, Compare to cluster

b0118 AcnB (EC 4.2.1.99) from Escherichia coli K-12 substr. MG1655
P36683 AcnB (EC 4.2.1.99) from Escherichia coli (strain K12)
ACNB_ECOLI / P36683 Aconitate hydratase B; ACN; Aconitase; (2R,3S)-2-methylisocitrate dehydratase; (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase; 2-methyl-cis-aconitate hydratase; Iron-responsive protein-like; IRP-like; RNA-binding protein; EC 4.2.1.3; EC 4.2.1.99 from Escherichia coli (strain K12)
P36683 aconitate hydratase (EC 4.2.1.3) from Escherichia coli
GB|AAZ86920.1 aconitate hydratas; EC 4.2.1.3 from Escherichia coli
PFams: Aconitase_B_N, Aconitase_2_N, Aconitase
865 amino acids: PaperBLAST, CDD, Compare to cluster

Q8ZRS8 aconitate hydratase 2 (EC 4.2.1.99) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
ACNB_SALTY / Q8ZRS8 Aconitate hydratase B; ACN; Aconitase; (2R,3S)-2-methylisocitrate dehydratase; (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate dehydratase; 2-methyl-cis-aconitate hydratase; Iron-responsive protein-like; IRP-like; RNA-binding protein; EC 4.2.1.3; EC 4.2.1.99 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
PFams: Aconitase_B_N, Aconitase_2_N, Aconitase
865 amino acids: PaperBLAST, CDD, Compare to cluster

P56418 aconitase (EC 4.2.1.3) from Helicobacter pylori (strain ATCC 700392 / 26695)
PFams: Aconitase_B_N, Aconitase_2_N, Aconitase
852 amino acids: PaperBLAST, CDD, Compare to cluster

Dshi_2060 Aconitate hydratase (EC 4.2.1.3) from Dinoroseobacter shibae DFL-12
PFams: Aconitase_B_N, Aconitase_2_N, Aconitase
930 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 4 483-484 amino acids (not heteromeric)

P74840 2-methylcitrate dehydratase (EC 4.2.1.79) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
PRPD_SALTY / P74840 2-methylcitrate dehydratase; 2-MC dehydratase; Aconitate hydratase; ACN; Aconitase; EC 4.2.1.79; EC 4.2.1.3 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
P74840 2-methylcitrate dehydratase (EC 4.2.1.79) from Salmonella enterica
PFams: MmgE_PrpD
483 amino acids: PaperBLAST, CDD, Compare to cluster

b0334 2-methylcitrate dehydratase (EC 4.2.1.79) from Escherichia coli K-12 substr. MG1655
P77243 2-methylcitrate dehydratase (EC 4.2.1.79) from Escherichia coli (strain K12)
PRPD_ECOLI / P77243 2-methylcitrate dehydratase; 2-MC dehydratase; (2S,3S)-2-methylcitrate dehydratase; Aconitate hydratase; ACN; Aconitase; EC 4.2.1.79; EC 4.2.1.3 from Escherichia coli (strain K12)
P77243 2-methylcitrate dehydratase (EC 4.2.1.79) from Escherichia coli
PDB|1SZQ 2-methylcitrate dehydratase; EC 4.2.1.79 from Escherichia coli K12
PFams: MmgE_PrpD
483 amino acids: PaperBLAST, CDD, Compare to cluster

PRPD_CUPNE / Q937N6 2-methylcitrate dehydratase; 2-MC dehydratase; Aconitate hydratase; ACN; Aconitase; EC 4.2.1.79; EC 4.2.1.3 from Cupriavidus necator (Alcaligenes eutrophus) (Ralstonia eutropha)
PFams: MmgE_PrpD
484 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 5 504-526 amino acids (not heteromeric)

PRPD_MYCTE / H8F0D6 2-methylcitrate dehydratase; 2-MC dehydratase; Aconitate hydratase; ACN; Aconitase; EC 4.2.1.79; EC 4.2.1.3 from Mycobacterium tuberculosis (strain ATCC 35801 / TMC 107 / Erdman)
PFams: MmgE_PrpD
505 amino acids: PaperBLAST, CDD, Compare to cluster

PRPD_MYCTU / O06582 2-methylcitrate dehydratase; 2-MC dehydratase; Aconitate hydratase; ACN; Aconitase; EC 4.2.1.79; EC 4.2.1.3 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
PFams: MmgE_PrpD
526 amino acids: PaperBLAST, CDD, Compare to cluster

PRPD2_CORGL / Q8NSL3 2-methylcitrate dehydratase 2; 2-MC dehydratase; Aconitate hydratase; ACN; Aconitase; EC 4.2.1.79; EC 4.2.1.3 from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
PFams: MmgE_PrpD
504 amino acids: PaperBLAST, CDD, Compare to cluster