Clusters of Characterized Proteins

GapMind for catabolism of small carbon sources

Clusters of Characterized Proteins

Clustering the characterized proteins for citM (citrate:cation:H+ symporter CitM) in citrate catabolism

Or see other characterized proteins similar to citM

Or see all steps for citrate catabolism

Or cluster curated proteins matching a keyword

Definition of citM

Curated sequence P55069: Mg(2+)/citrate complex secondary transporter. [Citrate or D-isocitrate]•M2+ (Mg2+ preferring):H+ symporter, CitM (transports Mg2+, Mn2+, Ni2+, Co2+ & Zn2+)
Curated sequence A4QA05: Citrate-inducible divalent cation:citrate uptake transporter, CitH
Curated sequence P42308: [Citrate]•M2+ (Ca2+ preferring):H+ symporter, CitH (transports Ca2+, Ba2+ & Sr2+)
Curated sequence Q9S242: Citrate-M2+ (Fe3+ preferring): H+ symporter, Cit (transports Fe3+, Ca2+, Pb2+, Ba2+ and Mn2+, but not Mg2+, Ni2+ or Co2+)
Curated sequence Q8DUC7: Citrate•Me2+ (Fe2+/Mn2+ preferring):H+ symporter, CitM
Comment: (Some of these were missed by the query, probably because the substrate field in TCDB mentions the cation only)

Fetched 5 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 5 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 426-526 amino acids (not heteromeric)

The first sequence in each cluster is the seed.

CITM_BACSU / P55069 Mg(2+)/citrate complex secondary transporter from Bacillus subtilis (strain 168)
TC 2.A.11.1.1 / P55069 [Citrate or D-isocitrate]•M2+ (Mg2+ preferring):H+ symporter, CitM (transports Mg2+, Mn2+, Ni2+, Co2+ & Zn2+) from Bacillus subtilis
PFams: CitMHS
433 amino acids: PaperBLAST, CDD, Compare to cluster

TC 2.A.11.1.6 / A4QA05 Citrate-inducible divalent cation:citrate uptake transporter, CitH from Corynebacterium glutamicum (strain R)
PFams: Na_H_antiporter, CitMHS
526 amino acids: PaperBLAST, CDD, Compare to cluster

TC 2.A.11.1.2 / P42308 [Citrate]•M2+ (Ca2+ preferring):H+ symporter, CitH (transports Ca2+, Ba2+ & Sr2+) from Bacillus subtilis
PFams: Na_H_antiporter, CitMHS
426 amino acids: PaperBLAST, CDD, Compare to cluster

TC 2.A.11.1.3 / Q8DUC7 Citrate•Me2+ (Fe2+/Mn2+ preferring):H+ symporter, CitM
PFams: CitMHS
467 amino acids: PaperBLAST, CDD, Compare to cluster

TC 2.A.11.1.4 / Q9S242 Citrate-M2+ (Fe3+ preferring): H+ symporter, Cit (transports Fe3+, Ca2+, Pb2+, Ba2+ and Mn2+, but not Mg2+, Ni2+ or Co2+) from Streptomyces coelicolor
PFams: Na_H_antiporter, CitMHS
483 amino acids: PaperBLAST, CDD, Compare to cluster