Clusters of Characterized Proteins

Clustering the characterized proteins for tctA (citrate/Na+ symporter, large transmembrane component TctA) in citrate catabolism

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Definition of tctA

• Curated sequence S5Y5N9: Citrate uptake transporter, membrane subunit, component of Pmf-dependent citrate uptake porter, TctABC
• Curated sequence Q9FA44: TctA, component of The tricarboxylate transporter, TctABC
• Curated sequence 3609738: Tricarboxylate transport membrane protein TctA
• UniProt sequence E4PJQ9: SubName: Full=Tricarboxylic transport TctA {ECO:0000313|EMBL:ADP98423.1};
• Comment: TctABC is also studied in S. typhimurium and D. shibae but was missed by the query. Fitness data confirms that HP15_2659:HP15_2661 (E4PJQ9,E4PJR0,E4PJR1) in Marinobacter adhaerens are tctABC

Fetched 4 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 4 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 504-510 amino acids (2/4 heteromeric)

TC 2.A.80.1.1 / Q9FA44 TctA, component of The tricarboxylate transporter, TctABC from Salmonella enterica
PFams: TctA
Heteromeric, 504 amino acids: PaperBLAST, CDD, Compare to cluster

TC 2.A.80.1.4 / S5Y5N9 Citrate uptake transporter, membrane subunit, component of Pmf-dependent citrate uptake porter, TctABC from Corynebacterium glutamicum MB001
PFams: TctA
Heteromeric, 510 amino acids: PaperBLAST, CDD, Compare to cluster

E4PJQ9 Tricarboxylic transport TctA
508 amino acids: PaperBLAST, CDD, Compare to cluster

Dshi_3121 Tricarboxylate transport membrane protein TctA from Dinoroseobacter shibae DFL-12
PFams: TctA
505 amino acids: PaperBLAST, CDD, Compare to cluster