GapMind for catabolism of small carbon sources

 

Clusters of Characterized Proteins

Clustering the characterized proteins for rocA (1-pyrroline-5-carboxylate dehydrogenase) in L-citrulline catabolism

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Definition of rocA

Fetched 23 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 22 of these sequences

Found 2 clusters of similar sequences. Another 1 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 1053-1333 amino acids (not heteromeric)

B1014 fused DNA-binding transcriptional repressor / proline dehydrogenase / 1-pyrroline-5-carboxylate dehydrogenase PutA (EC 1.5.5.2; EC 1.2.1.88) from Escherichia coli K-12 substr. MG1655
P09546 fused DNA-binding transcriptional repressor / proline dehydrogenase / 1-pyrroline-5-carboxylate dehydrogenase PutA (EC 1.5.5.2; EC 1.2.1.88) from Escherichia coli (strain K12)
PUTA_ECOLI / P09546 Bifunctional protein PutA; EC 1.5.5.2; EC 1.2.1.88 from Escherichia coli (strain K12)
P09546 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88); proline dehydrogenase (EC 1.5.5.2) from Escherichia coli
GB|BAA35791.1 proline dehydrogenase/delta-1-pyrroline-5-carboxylate dehydrogenase; EC 1.5.1.12; EC 1.5.99.8 from Escherichia coli K12
PFams: PRODH, Pro_dh-DNA_bdg, Pro_dh, Aldedh
1320 amino acids: PaperBLAST, CDD, Compare to cluster

Shewana3_0819 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88); Proline dehydrogenase (EC 1.5.5.2) from Shewanella sp. ANA-3
PFams: Pro_dh-DNA_bdg, Pro_dh, Aldedh
1064 amino acids: PaperBLAST, CDD, Compare to cluster

RR42_RS20125 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88); Proline dehydrogenase (EC 1.5.5.2) from Cupriavidus basilensis 4G11
PFams: PRODH, Pro_dh-DNA_bdg, Pro_dh, Aldedh
1333 amino acids: PaperBLAST, CDD, Compare to cluster

HSERO_RS00905 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88); Proline dehydrogenase (EC 1.5.5.2) from Herbaspirillum seropedicae SmR1
PFams: PRODH, Pro_dh-DNA_bdg, Pro_dh, Aldedh
1230 amino acids: PaperBLAST, CDD, Compare to cluster

BWI76_RS10795 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88); Proline dehydrogenase (EC 1.5.5.2) from Klebsiella michiganensis M5al
PFams: PRODH, Pro_dh-DNA_bdg, Pro_dh, Aldedh
1320 amino acids: PaperBLAST, CDD, Compare to cluster

HP15_2688 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88); Proline dehydrogenase (EC 1.5.5.2) from Marinobacter adhaerens HP15
PFams: PRODH, Pro_dh-DNA_bdg, Pro_dh, Aldedh
1209 amino acids: PaperBLAST, CDD, Compare to cluster

PGA1_c11750 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88); Proline dehydrogenase (EC 1.5.5.2) from Phaeobacter inhibens BS107
PFams: Pro_dh-DNA_bdg, Pro_dh, Aldedh
1158 amino acids: PaperBLAST, CDD, Compare to cluster

Sama_2676 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88); Proline dehydrogenase (EC 1.5.5.2) from Shewanella amazonensis SB2B
PFams: Pro_dh-DNA_bdg, Pro_dh, Aldedh
1058 amino acids: PaperBLAST, CDD, Compare to cluster

Ac3H11_2850 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88); Proline dehydrogenase (EC 1.5.5.2) from Acidovorax sp. GW101-3H11
PFams: PRODH, Pro_dh-DNA_bdg, Pro_dh, Aldedh
1261 amino acids: PaperBLAST, CDD, Compare to cluster

AZOBR_RS23695 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88); Proline dehydrogenase (EC 1.5.5.2) from Azospirillum brasilense Sp245
PFams: PRODH, Pro_dh-DNA_bdg, Pro_dh, Aldedh
1235 amino acids: PaperBLAST, CDD, Compare to cluster

Psest_3079 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88); Proline dehydrogenase (EC 1.5.5.2) from Pseudomonas stutzeri RCH2
PFams: PRODH, Pro_dh-DNA_bdg, Pro_dh, Aldedh
1053 amino acids: PaperBLAST, CDD, Compare to cluster

AO353_12810 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88); Proline dehydrogenase (EC 1.5.5.2) from Pseudomonas fluorescens FW300-N2E3
PFams: PRODH, Pro_dh-DNA_bdg, Pro_dh, Aldedh
1317 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 515-575 amino acids (not heteromeric)

P07275 Δ1-pyrroline-5-carboxylate dehydrogenase (EC 1.2.1.88) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
PUT2_YEAST / P07275 Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; P5C dehydrogenase; L-glutamate gamma-semialdehyde dehydrogenase; EC 1.2.1.88 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
P07275 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88) from Saccharomyces cerevisiae
PFams: Aldedh
575 amino acids: PaperBLAST, CDD, Compare to cluster

P30038 Δ1-pyrroline-5-carboxylate dehydrogenase, mitochondrial subunit (EC 1.2.1.88) from Homo sapiens
AL4A1_HUMAN / P30038 Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; P5C dehydrogenase; Aldehyde dehydrogenase family 4 member A1; L-glutamate gamma-semialdehyde dehydrogenase; EC 1.2.1.88 from Homo sapiens (Human)
P30038 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88) from Homo sapiens
PFams: Aldedh
563 amino acids: PaperBLAST, CDD, Compare to cluster

Q4DRT8 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88) from Trypanosoma cruzi
PFams: Aldedh
561 amino acids: PaperBLAST, CDD, Compare to cluster

Q65NN2 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88) from Bacillus licheniformis
PFams: Aldedh
516 amino acids: PaperBLAST, CDD, Compare to cluster

Q72IB9 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88) from Thermus thermophilus
PFams: Aldedh
516 amino acids: PaperBLAST, CDD, Compare to cluster

Q9K9B2 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88) from Bacillus halodurans
PFams: Aldedh
515 amino acids: PaperBLAST, CDD, Compare to cluster

Q9RW56 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88) from Deinococcus radiodurans
PFams: Aldedh
523 amino acids: PaperBLAST, CDD, Compare to cluster

CH_122352 delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; EC 1.5.1.12 (from HMM only) from Emericella nidulans
PFams: Aldedh
572 amino acids: PaperBLAST, CDD, Compare to cluster

ROCA2_BACSU / P94391 1-pyrroline-5-carboxylate dehydrogenase 2; P5C dehydrogenase 2; L-glutamate gamma-semialdehyde dehydrogenase; EC 1.2.1.88 from Bacillus subtilis (strain 168)
PFams: Aldedh
515 amino acids: PaperBLAST, CDD, Compare to cluster

AL4A1_MOUSE / Q8CHT0 Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial; P5C dehydrogenase; Aldehyde dehydrogenase family 4 member A1; L-glutamate gamma-semialdehyde dehydrogenase; EC 1.2.1.88 from Mus musculus (Mouse)
Q8CHT0 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88) from Mus musculus
PFams: Aldedh
562 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/1 heteromeric)

AL121_ARATH / Q8VZC3 Delta-1-pyrroline-5-carboxylate dehydrogenase 12A1, mitochondrial; AtP5CDH; P5C dehydrogenase; Aldehyde dehydrogenase family 12 member A1; L-glutamate gamma-semialdehyde dehydrogenase; EC 1.2.1.88 from Arabidopsis thaliana (Mouse-ear cress)
Q8VZC3 L-glutamate gamma-semialdehyde dehydrogenase (EC 1.2.1.88) from Arabidopsis thaliana
PFams: Aldedh
556 amino acids: PaperBLAST, CDD