Clusters of Characterized Proteins

GapMind for catabolism of small carbon sources

Clusters of Characterized Proteins

Clustering the characterized proteins for etoh-dh-nad (ethanol dehydrogenase (NAD(P))) in ethanol catabolism

Or see other characterized proteins similar to etoh-dh-nad

Or see all steps for ethanol catabolism

Or cluster curated proteins matching a keyword

Definition of etoh-dh-nad

Curated proteins or TIGRFams with EC 1.1.1.1
Ignore hits to CH_121261 when looking for 'other' hits (NAD-dependent alcohol dehydrogenase; EC 1.1.1.1)
Curated proteins or TIGRFams with EC 1.1.1.71
Comment: CH_121261 seems to be a sequence fragment

Fetched 126 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 119 of these sequences

Found 11 clusters of similar sequences. Another 8 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 333-388 amino acids (not heteromeric)

P42328 alcohol dehydrogenase (EC 1.1.1.1) from Geobacillus stearothermophilus
PFams: ADH_N, ADH_zinc_N, ADH_zinc_N_2
339 amino acids: PaperBLAST, CDD, Compare to cluster

A0A060TBM3 alcohol dehydrogenase (EC 1.1.1.1) from Blastobotrys adeninivorans
PFams: ADH_N, ADH_zinc_N
348 amino acids: PaperBLAST, CDD, Compare to cluster

A0A1D8PP43 alcohol dehydrogenase (EC 1.1.1.1); 2-oxoaldehyde dehydrogenase (NAD+) (EC 1.2.1.23) from Candida albicans
PFams: ADH_N, ADH_zinc_N, ADH_zinc_N_2
350 amino acids: PaperBLAST, CDD, Compare to cluster

A1IIA3 alcohol dehydrogenase (EC 1.1.1.1) from Kluyveromyces marxianus
PFams: ADH_N, ADH_zinc_N, ADH_zinc_N_2
375 amino acids: PaperBLAST, CDD, Compare to cluster

A1IIA4 alcohol dehydrogenase (EC 1.1.1.1) from Kluyveromyces marxianus
PFams: ADH_N, ADH_zinc_N
379 amino acids: PaperBLAST, CDD, Compare to cluster

A3MVR8 alcohol dehydrogenase (EC 1.1.1.1) from Pyrobaculum calidifontis
PFams: ADH_N, ADH_zinc_N, ADH_zinc_N_2
348 amino acids: PaperBLAST, CDD, Compare to cluster

B2ZRE3 alcohol dehydrogenase (EC 1.1.1.1) from Thermus sp.
PFams: ADH_N, AlaDh_PNT_C, Glu_dehyd_C, ADH_zinc_N, ADH_zinc_N_2
347 amino acids: PaperBLAST, CDD, Compare to cluster

B6UQD0 alcohol dehydrogenase (EC 1.1.1.1) from Saccharomyces pastorianus
PFams: ADH_N, ADH_zinc_N
348 amino acids: PaperBLAST, CDD, Compare to cluster

C7R702 alcohol dehydrogenase (EC 1.1.1.1); all-trans-retinol dehydrogenase (NAD+) (EC 1.1.1.105) from Kangiella koreensis
PFams: ADH_N, ADH_zinc_N
374 amino acids: PaperBLAST, CDD, Compare to cluster

D4GSN2 alcohol dehydrogenase (EC 1.1.1.1) from Haloferax volcanii
PFams: ADH_N, ADH_zinc_N
353 amino acids: PaperBLAST, CDD, Compare to cluster

F9VMI9 alcohol dehydrogenase (EC 1.1.1.1) from Sulfurisphaera tokodaii
PFams: ADH_N, ADH_zinc_N, ADH_zinc_N_2
344 amino acids: PaperBLAST, CDD, Compare to cluster

G3FFC9 alcohol dehydrogenase (EC 1.1.1.1) from Kluyveromyces marxianus
PFams: ADH_N, ADH_zinc_N, ADH_zinc_N_2
348 amino acids: PaperBLAST, CDD, Compare to cluster

H9ZGN0 alcohol dehydrogenase (EC 1.1.1.1) from Ogataea angusta
PFams: ADH_N, ADH_zinc_N
381 amino acids: PaperBLAST, CDD, Compare to cluster

ADH1G_HUMAN / P00326 Alcohol dehydrogenase 1C; Alcohol dehydrogenase subunit gamma; EC 1.1.1.1 from Homo sapiens (Human)
P00326 alcohol dehydrogenase (EC 1.1.1.1) from Homo sapiens
PFams: ADH_N, ADH_zinc_N
375 amino acids: PaperBLAST, CDD, Compare to cluster

P39462 alcohol dehydrogenase (EC 1.1.1.1) from Saccharolobus solfataricus
PFams: ADH_N, ADH_zinc_N, ADH_zinc_N_2
347 amino acids: PaperBLAST, CDD, Compare to cluster

P50381 alcohol dehydrogenase (EC 1.1.1.1) from Sulfolobus sp.
PFams: ADH_N, ADH_zinc_N, ADH_zinc_N_2
347 amino acids: PaperBLAST, CDD, Compare to cluster

P86883 alcohol dehydrogenase (EC 1.1.1.1) from Columba livia
PFams: ADH_N, ADH_zinc_N
375 amino acids: PaperBLAST, CDD, Compare to cluster

Q6RS93 alcohol dehydrogenase (EC 1.1.1.1) from Parageobacillus thermoglucosidasius
PFams: ADH_N, ADH_zinc_N, ADH_zinc_N_2
340 amino acids: PaperBLAST, CDD, Compare to cluster

Q8H0L8 alcohol dehydrogenase [NAD(P)+] (EC 1.1.1.71) from Solanum tuberosum
PFams: ADH_N, ADH_zinc_N
359 amino acids: PaperBLAST, CDD, Compare to cluster

Q8KLT9 alcohol dehydrogenase (EC 1.1.1.1) from Rhodococcus ruber
PFams: ADH_N, ADH_zinc_N, ADH_zinc_N_2
346 amino acids: PaperBLAST, CDD, Compare to cluster

Q8L3C9 alcohol dehydrogenase (EC 1.1.1.1) from Flavobacterium frigidimaris
PFams: ADH_N, ADH_zinc_N
344 amino acids: PaperBLAST, CDD, Compare to cluster

Q9CEN0 alcohol dehydrogenase (EC 1.1.1.1) from Lactococcus lactis subsp. lactis
PFams: ADH_N, ADH_zinc_N
340 amino acids: PaperBLAST, CDD, Compare to cluster

Q9P6C8 alcohol dehydrogenase (EC 1.1.1.1) from Neurospora crassa
PFams: ADH_N, ADH_zinc_N, ADH_zinc_N_2
353 amino acids: PaperBLAST, CDD, Compare to cluster

Q9UXF1 alcohol dehydrogenase (EC 1.1.1.1) from Saccharolobus solfataricus
PFams: ADH_N, CMAS, ADH_zinc_N, ADH_zinc_N_2
333 amino acids: PaperBLAST, CDD, Compare to cluster

Q9Y9P9 alcohol dehydrogenase (EC 1.1.1.1) from Aeropyrum pernix
PFams: ADH_N, ADH_zinc_N, ADH_zinc_N_2
344 amino acids: PaperBLAST, CDD, Compare to cluster

V9SCJ1 alcohol dehydrogenase (EC 1.1.1.1) from Kluyveromyces marxianus
PFams: ADH_N, ADH_zinc_N, ADH_zinc_N_2
375 amino acids: PaperBLAST, CDD, Compare to cluster

W6CX26 alcohol dehydrogenase (EC 1.1.1.1); aryl-alcohol dehydrogenase (EC 1.1.1.90); aryl-alcohol dehydrogenase (NADP+) (EC 1.1.1.91) from Yokenella sp.
PFams: ADH_N, 2-Hacid_dh_C, AlaDh_PNT_C, ADH_zinc_N, ADH_zinc_N_2
339 amino acids: PaperBLAST, CDD, Compare to cluster

W8VSK8 alcohol dehydrogenase (EC 1.1.1.1); diacetyl reductase [(S)-acetoin forming] (EC 1.1.1.304); (S,S)-butanediol dehydrogenase (EC 1.1.1.76) from Mycobacterium sp.
PFams: ADH_N, ADH_zinc_N, ADH_zinc_N_2
344 amino acids: PaperBLAST, CDD, Compare to cluster

CH_122079 alcohol dehydrogenase 1; EC 1.1.1.1 from Emericella nidulans
PFams: ADH_N, ADH_zinc_N
350 amino acids: PaperBLAST, CDD, Compare to cluster

CH_122310 alcohol dehydrogenase 2; EC 1.1.1.1 from Emericella nidulans
PFams: ADH_N, ADH_zinc_N
367 amino acids: PaperBLAST, CDD, Compare to cluster

GB|CAA21988.1 alcohol dehydrogenase 2; EC 1.1.1.1 from Candida albicans
PFams: ADH_N, ADH_zinc_N, ADH_zinc_N_2
348 amino acids: PaperBLAST, CDD, Compare to cluster

PATD_PENEN / A0A075TMP0 Alcohol dehydrogenase patD; Patulin biosynthesis cluster protein D; EC 1.1.1.1 from Penicillium expansum (Blue mold rot fungus)
PFams: ADH_N, ADH_zinc_N
340 amino acids: PaperBLAST, CDD, Compare to cluster

PATD_ASPCL / A1CFL1 Alcohol dehydrogenase patD; Patulin synthesis protein D; EC 1.1.1.1 from Aspergillus clavatus (strain ATCC 1007 / CBS 513.65 / DSM 816 / NCTC 3887 / NRRL 1)
PFams: ADH_N, ADH_zinc_N
388 amino acids: PaperBLAST, CDD, Compare to cluster

NOTN_ASPSM / E1ACQ9 Alcohol dehydrogenase notN; Notoamide biosynthesis cluster protein N; EC 1.1.1.1 from Aspergillus sp. (strain MF297-2)
PFams: ADH_N, ADH_zinc_N
339 amino acids: PaperBLAST, CDD, Compare to cluster

ADH2_YARLI / F2Z678 Alcohol dehydrogenase 2; EC 1.1.1.1 from Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
PFams: ADH_N, ADH_zinc_N
351 amino acids: PaperBLAST, CDD, Compare to cluster

P00325 alcohol dehydrogenase β subunit (EC 1.1.1.1; EC 1.1.1.80) from Homo sapiens
ADH1B_HUMAN / P00325 All-trans-retinol dehydrogenase [NAD(+)] ADH1B; Alcohol dehydrogenase 1B; Alcohol dehydrogenase subunit beta; EC 1.1.1.105 from Homo sapiens (Human)
PFams: ADH_N, ADH_zinc_N
375 amino acids: PaperBLAST, CDD, Compare to cluster

ADH1E_HORSE / P00327 Alcohol dehydrogenase E chain; EC 1.1.1.1 from Equus caballus (Horse)
PFams: ADH_N, ADH_zinc_N
375 amino acids: PaperBLAST, CDD, Compare to cluster

ADH1_MOUSE / P00329 Alcohol dehydrogenase 1; ADH-A2; Alcohol dehydrogenase A subunit; EC 1.1.1.1 from Mus musculus (Mouse)
PFams: ADH_N, ADH_zinc_N, ADH_zinc_N_2
375 amino acids: PaperBLAST, CDD, Compare to cluster

P00331 alcohol dehydrogenase II (EC 1.1.1.1; EC 1.1.1.190) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
ADH2_YEAST / P00331 Alcohol dehydrogenase 2; Alcohol dehydrogenase II; YADH-2; EC 1.1.1.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: ADH_N, ADH_zinc_N, ADH_zinc_N_2
348 amino acids: PaperBLAST, CDD, Compare to cluster

ADH1_ARATH / P06525 Alcohol dehydrogenase class-P; AtADH; EC 1.1.1.1 from Arabidopsis thaliana (Mouse-ear cress)
PFams: ADH_N, ADH_zinc_N
379 amino acids: PaperBLAST, CDD, Compare to cluster

P07246 alcohol dehydrogenase III (EC 1.1.1.1; EC 1.1.1.190) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
ADH3_YEAST / P07246 Alcohol dehydrogenase 3, mitochondrial; Alcohol dehydrogenase III; YADH-3; EC 1.1.1.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: ADH_N, ADH_zinc_N
375 amino acids: PaperBLAST, CDD, Compare to cluster

ADH1A_HUMAN / P07327 Alcohol dehydrogenase 1A; Alcohol dehydrogenase subunit alpha; EC 1.1.1.1 from Homo sapiens (Human)
PFams: ADH_N, ADH_zinc_N
375 amino acids: PaperBLAST, CDD, Compare to cluster

ADH2_HORVU / P10847 Alcohol dehydrogenase 2; EC 1.1.1.1 from Hordeum vulgare (Barley)
PFams: ADH_N, ADH_zinc_N
373 amino acids: PaperBLAST, CDD, Compare to cluster

ADH3_HORVU / P10848 Alcohol dehydrogenase 3; EC 1.1.1.1 from Hordeum vulgare (Barley)
PFams: ADH_N, ADH_zinc_N
379 amino acids: PaperBLAST, CDD, Compare to cluster

P12886 alcohol dehydrogenase (EC 1.1.1.1) from Pisum sativum
ADH1_PEA / P12886 Alcohol dehydrogenase 1; EC 1.1.1.1 from Pisum sativum (Garden pea)
PFams: ADH_N, ADH_zinc_N
380 amino acids: PaperBLAST, CDD, Compare to cluster

P14673 alcohol dehydrogenase (EC 1.1.1.1) from Solanum tuberosum
ADH1_SOLTU / P14673 Alcohol dehydrogenase 1; EC 1.1.1.1 from Solanum tuberosum (Potato)
PFams: ADH_N, ADH_zinc_N
380 amino acids: PaperBLAST, CDD, Compare to cluster

ADH1_PETHY / P25141 Alcohol dehydrogenase 1; EC 1.1.1.1 from Petunia hybrida (Petunia)
PFams: ADH_N, ADH_zinc_N
382 amino acids: PaperBLAST, CDD, Compare to cluster

P38113 alcohol dehydrogenase V (EC 1.1.1.1; EC 1.1.1.190) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
ADH5_YEAST / P38113 Alcohol dehydrogenase 5; Alcohol dehydrogenase V; EC 1.1.1.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: ADH_N, ADH_zinc_N
351 amino acids: PaperBLAST, CDD, Compare to cluster

ADHX_DROME / P46415 Alcohol dehydrogenase class-3; Alcohol dehydrogenase class-III; Glutathione-dependent formaldehyde dehydrogenase; FALDH; FDH; GSH-FDH; Octanol dehydrogenase; S-(hydroxymethyl)glutathione dehydrogenase; EC 1.1.1.1; EC 1.1.1.-; EC 1.1.1.73; EC 1.1.1.284 from Drosophila melanogaster (Fruit fly)
PFams: ADH_N, ADH_zinc_N
379 amino acids: PaperBLAST, CDD, Compare to cluster

ADHD_MYCTU / P9WQB9 Putative alcohol dehydrogenase D; EC 1.1.1.1 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
PFams: ADH_N, ADH_zinc_N, ADH_zinc_N_2
368 amino acids: PaperBLAST, CDD, Compare to cluster

ADH2_ORYSI / Q4R1E8 Alcohol dehydrogenase 2; EC 1.1.1.1 from Oryza sativa subsp. indica (Rice)
PFams: ADH_N, ADH_zinc_N
379 amino acids: PaperBLAST, CDD, Compare to cluster

TDH_PYRFU / Q8U259 L-threonine 3-dehydrogenase; TDH; L-threonine dehydrogenase; EC 1.1.1.103 from Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1)
Q8U259 alcohol dehydrogenase (EC 1.1.1.1) from Pyrococcus furiosus
PFams: ADH_N, Glu_dehyd_C, ADH_zinc_N, ADH_zinc_N_2
348 amino acids: PaperBLAST, CDD, Compare to cluster

b1478 ethanol dehydrogenase / alcohol dehydrogenase (EC 1.1.1.1) from Escherichia coli K-12 substr. MG1655
P39451 ethanol dehydrogenase / alcohol dehydrogenase (EC 1.1.1.1) from Escherichia coli (strain K12)
PFams: ADH_N, ADH_zinc_N, ADH_zinc_N_2
336 amino acids: PaperBLAST, CDD, Compare to cluster

Q8NLX9 Zn²⁺-dependent alcohol dehydrogenase (EC 1.1.1.1; EC 1.1.1.244) from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
PFams: ADH_N, ADH_zinc_N
345 amino acids: PaperBLAST, CDD, Compare to cluster

Q8NTI8 mycothiol-dependent formaldehyde dehydrogenase subunit (EC 1.1.1.1; EC 1.1.1.306) from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025)
PFams: ADH_N, ADH_zinc_N
368 amino acids: PaperBLAST, CDD, Compare to cluster

Q6IVK8 alcohol dehydrogenase (EC 1.1.1.1; EC 1.1.1.22) from Nicotiana tabacum
Q6IVK8 UDP-glucose 6-dehydrogenase (EC 1.1.1.22) from Nicotiana tabacum
PFams: ADH_N, ADH_zinc_N
380 amino acids: PaperBLAST, CDD, Compare to cluster

Q46UZ9 furfuryl alcohol dehydrogenase (EC 1.1.1.1) from Cupriavidus pinatubonensis (strain JMP 134 / LMG 1197)
PFams: ADH_N, ADH_zinc_N, ADH_zinc_N_2
342 amino acids: PaperBLAST, CDD, Compare to cluster

P00330 alcohol dehydrogenase 1 (EC 1.1.1.1; EC 1.1.1.190) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
PFams: ADH_N, ADH_zinc_N
348 amino acids: PaperBLAST, CDD, Compare to cluster

RR42_RS34260 Alcohol dehydrogenase (EC 1.1.1.1) from Cupriavidus basilensis 4G11
PFams: ADH_N, ADH_zinc_N
342 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 347-386 amino acids (not heteromeric)

b0356 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) from Escherichia coli K-12 substr. MG1655
P25437 S-(hydroxymethyl)glutathione dehydrogenase (EC 1.1.1.284) from Escherichia coli (strain K12)
FRMA_ECOLI / P25437 S-(hydroxymethyl)glutathione dehydrogenase; Alcohol dehydrogenase class-3; Alcohol dehydrogenase class-III; Glutathione-dependent formaldehyde dehydrogenase; FALDH; FDH; GSH-FDH; EC 1.1.1.284; EC 1.1.1.1; EC 1.1.1.- from Escherichia coli (strain K12)
GB|BAA22412.1 S-(hydroxymethyl)glutathione dehydrogenase; EC 1.1.1.-; EC 1.1.1.1; EC 1.1.1.284 from Escherichia coli K12
PFams: ADH_N, ADH_zinc_N
369 amino acids: PaperBLAST, CDD, Compare to cluster

P08319 alcohol dehydrogenase 4 subunit (EC 1.1.1.1) from Homo sapiens
ADH4_HUMAN / P08319 All-trans-retinol dehydrogenase [NAD(+)] ADH4; Alcohol dehydrogenase 4; Alcohol dehydrogenase class II pi chain; EC 1.1.1.105 from Homo sapiens (Human)
P08319 alcohol dehydrogenase (EC 1.1.1.1) from Homo sapiens
PFams: ADH_N, ADH_zinc_N
380 amino acids: PaperBLAST, CDD, Compare to cluster

P86884 alcohol dehydrogenase (EC 1.1.1.1) from Scyliorhinus canicula
PFams: ADH_N, ADH_zinc_N
376 amino acids: PaperBLAST, CDD, Compare to cluster

Q9HMB6 alcohol dehydrogenase [NAD(P)+] (EC 1.1.1.71) from Halobacterium sp.
PFams: ADH_N_assoc, ADH_N, ADH_zinc_N
347 amino acids: PaperBLAST, CDD, Compare to cluster

P00333 alcohol dehydrogenase (EC 1.1.1.1) from Zea mays
ADH1_MAIZE / P00333 Alcohol dehydrogenase 1; EC 1.1.1.1 from Zea mays (Maize)
PFams: ADH_N, ADH_zinc_N
379 amino acids: PaperBLAST, CDD, Compare to cluster

ADH1_HORVU / P05336 Alcohol dehydrogenase 1; EC 1.1.1.1 from Hordeum vulgare (Barley)
PFams: ADH_N, ADH_zinc_N
379 amino acids: PaperBLAST, CDD, Compare to cluster

P11766 alcohol dehydrogenase class-3 monomer (EC 1.1.1.284) from Homo sapiens
ADHX_HUMAN / P11766 Alcohol dehydrogenase class-3; Alcohol dehydrogenase 5; Alcohol dehydrogenase class chi chain; Alcohol dehydrogenase class-III; Glutathione-dependent formaldehyde dehydrogenase; FALDH; FDH; GSH-FDH; S-(hydroxymethyl)glutathione dehydrogenase; EC 1.1.1.1; EC 1.1.1.-; EC 1.1.1.284 from Homo sapiens (Human)
PFams: ADH_N, ADH_zinc_N
374 amino acids: PaperBLAST, CDD, Compare to cluster

ADHX_MOUSE / P28474 Alcohol dehydrogenase class-3; Alcohol dehydrogenase 2; Alcohol dehydrogenase 5; Alcohol dehydrogenase B2; ADH-B2; Alcohol dehydrogenase class-III; Glutathione-dependent formaldehyde dehydrogenase; FALDH; FDH; GSH-FDH; S-(hydroxymethyl)glutathione dehydrogenase; EC 1.1.1.1; EC 1.1.1.-; EC 1.1.1.284 from Mus musculus (Mouse)
PFams: ADH_N, ADH_zinc_N
374 amino acids: PaperBLAST, CDD, Compare to cluster

P32771 S-(hydroxymethyl)glutathione dehydrogenase subunit (EC 1.1.1.284; EC 1.1.1.1; EC 1.1.1.190) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
FADH_YEAST / P32771 S-(hydroxymethyl)glutathione dehydrogenase; Alcohol dehydrogenase SFA; Glutathione-dependent formaldehyde dehydrogenase; FALDH; FDH; FLD; GSH-FDH; EC 1.1.1.284; EC 1.1.1.1; EC 1.1.1.- from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: ADH_N, ADH_zinc_N
386 amino acids: PaperBLAST, CDD, Compare to cluster

ADH7_HUMAN / P40394 All-trans-retinol dehydrogenase [NAD(+)] ADH7; Alcohol dehydrogenase class 4 mu/sigma chain; Alcohol dehydrogenase class IV mu/sigma chain; Gastric alcohol dehydrogenase; Omega-hydroxydecanoate dehydrogenase ADH7; Retinol dehydrogenase; EC 1.1.1.105; EC 1.1.1.1; EC 1.1.1.66 from Homo sapiens (Human)
PFams: ADH_N, ADH_zinc_N
386 amino acids: PaperBLAST, CDD, Compare to cluster

ADH7_RAT / P41682 All-trans-retinol dehydrogenase [NAD(+)] ADH7; Alcohol dehydrogenase class 4 mu/sigma chain; Alcohol dehydrogenase class IV mu/sigma chain; Omega-hydroxydecanoate dehydrogenase ADH7; EC 1.1.1.105; EC 1.1.1.1; EC 1.1.1.66 from Rattus norvegicus (Rat)
PFams: ADH_N, ADH_zinc_N
374 amino acids: PaperBLAST, CDD, Compare to cluster

ADHX_SPAAU / P79896 Alcohol dehydrogenase class-3; Alcohol dehydrogenase class-III; Glutathione-dependent formaldehyde dehydrogenase; FALDH; FDH; GSH-FDH; S-(hydroxymethyl)glutathione dehydrogenase; EC 1.1.1.1; EC 1.1.1.-; EC 1.1.1.284 from Sparus aurata (Gilthead sea bream)
PFams: ADH_N, ADH_zinc_N
376 amino acids: PaperBLAST, CDD, Compare to cluster

ADHX_MYXGL / P80360 Alcohol dehydrogenase class-3; Alcohol dehydrogenase class-III; Glutathione-dependent formaldehyde dehydrogenase; FALDH; FDH; GSH-FDH; S-(hydroxymethyl)glutathione dehydrogenase; EC 1.1.1.1; EC 1.1.1.-; EC 1.1.1.284 from Myxine glutinosa (Atlantic hagfish)
PFams: ADH_N, ADH_zinc_N
376 amino acids: PaperBLAST, CDD, Compare to cluster

ADHX_PEA / P80572 Alcohol dehydrogenase class-3; Alcohol dehydrogenase class-III; Glutathione-dependent formaldehyde dehydrogenase; FALDH; FDH; GSH-FDH; S-(hydroxymethyl)glutathione dehydrogenase; EC 1.1.1.1; EC 1.1.1.-; EC 1.1.1.284 from Pisum sativum (Garden pea)
PFams: ADH_N, ADH_zinc_N
378 amino acids: PaperBLAST, CDD, Compare to cluster

ADHH_GADMO / P81600 Alcohol dehydrogenase class-3 chain H; Alcohol dehydrogenase class-III chain H; Glutathione-dependent formaldehyde dehydrogenase; FALDH; FDH; GSH-FDH; S-(hydroxymethyl)glutathione dehydrogenase; EC 1.1.1.1; EC 1.1.1.-; EC 1.1.1.284 from Gadus morhua (Atlantic cod)
PFams: ADH_N, ADH_zinc_N
375 amino acids: PaperBLAST, CDD, Compare to cluster

ADHL_GADMO / P81601 Alcohol dehydrogenase class-3 chain L; Alcohol dehydrogenase class-III chain L; Glutathione-dependent formaldehyde dehydrogenase; FALDH; FDH; GSH-FDH; S-(hydroxymethyl)glutathione dehydrogenase; EC 1.1.1.1; EC 1.1.1.-; EC 1.1.1.284 from Gadus morhua (Atlantic cod)
PFams: ADH_N, ADH_zinc_N
375 amino acids: PaperBLAST, CDD, Compare to cluster

ADHX_MAIZE / P93629 Alcohol dehydrogenase class-3; Alcohol dehydrogenase class-III; Glutathione-dependent formaldehyde dehydrogenase; FALDH; FDH; GSH-FDH; S-(hydroxymethyl)glutathione dehydrogenase; EC 1.1.1.1; EC 1.1.1.-; EC 1.1.1.284 from Zea mays (Maize)
PFams: ADH_N, ADH_zinc_N
381 amino acids: PaperBLAST, CDD, Compare to cluster

ADHX_CAEEL / Q17335 Alcohol dehydrogenase class-3; Alcohol dehydrogenase class-III; Glutathione-dependent formaldehyde dehydrogenase; FALDH; FDH; GSH-FDH; S-(hydroxymethyl)glutathione dehydrogenase; EC 1.1.1.1; EC 1.1.1.-; EC 1.1.1.284 from Caenorhabditis elegans
PFams: ADH_N, ADH_zinc_N
384 amino acids: PaperBLAST, CDD, Compare to cluster

ADH1_ORYSI / Q75ZX4 Alcohol dehydrogenase 1; EC 1.1.1.1 from Oryza sativa subsp. indica (Rice)
PFams: ADH_N, ADH_zinc_N
379 amino acids: PaperBLAST, CDD, Compare to cluster

ADHX_ARATH / Q96533 Alcohol dehydrogenase class-3; Alcohol dehydrogenase class-III; Glutathione-dependent formaldehyde dehydrogenase; FALDH; FDH; GSH-FDH; S-(hydroxymethyl)glutathione dehydrogenase; EC 1.1.1.1; EC 1.1.1.-; EC 1.1.1.284 from Arabidopsis thaliana (Mouse-ear cress)
PFams: ADH_N, ADH_zinc_N
379 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 3 859-954 amino acids (not heteromeric)

A0A0H3W5K4 acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Thermoanaerobacterium saccharolyticum
I3VSF1 alcohol dehydrogenase (EC 1.1.1.1); L-lactate dehydrogenase (EC 1.1.1.27); acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Thermoanaerobacterium saccharolyticum
PFams: Aldedh, Fe-ADH, Fe-ADH_2, Fe-ADH_2
859 amino acids: PaperBLAST, CDD, Compare to cluster

A0A0H3W5U9 alcohol dehydrogenase [NAD(P)+] (EC 1.1.1.71); acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Hungateiclostridium thermocellum
A3DCI2 alcohol dehydrogenase (EC 1.1.1.1); acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Hungateiclostridium thermocellum
PFams: Aldedh, Fe-ADH, Fe-ADH_2, Fe-ADH_2
873 amino acids: PaperBLAST, CDD, Compare to cluster

A0A0H3W5V0 alcohol dehydrogenase [NAD(P)+] (EC 1.1.1.71) from Thermoanaerobacterium saccharolyticum
PFams: Aldedh, Fe-ADH, Fe-ADH_2, Fe-ADH_2
859 amino acids: PaperBLAST, CDD, Compare to cluster

B0K4A2 alcohol dehydrogenase (EC 1.1.1.1); acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Thermoanaerobacter sp. X514
PFams: Aldedh, Fe-ADH, Fe-ADH_2, Fe-ADH_2
872 amino acids: PaperBLAST, CDD, Compare to cluster

B0KBJ9 alcohol dehydrogenase (EC 1.1.1.1) from Thermoanaerobacter pseudethanolicus
PFams: Aldedh, Fe-ADH, Fe-ADH_2, Fe-ADH_2
872 amino acids: PaperBLAST, CDD, Compare to cluster

C7IV28 alcohol dehydrogenase (EC 1.1.1.1); acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Thermoanaerobacter ethanolicus
PFams: Aldedh, Fe-ADH, Fe-ADH_2, Fe-ADH_2
872 amino acids: PaperBLAST, CDD, Compare to cluster

Q0PH30 alcohol dehydrogenase (EC 1.1.1.1) from Thermoanaerobacter ethanolicus
PFams: Aldedh, Fe-ADH, Fe-ADH_2, Fe-ADH_2
874 amino acids: PaperBLAST, CDD, Compare to cluster

Q70YJ9 alcohol dehydrogenase (EC 1.1.1.1); acetaldehyde dehydrogenase (acetylating) (EC 1.2.1.10) from Polytomella sp. Pringsheim 198.80
PFams: Aldedh, Fe-ADH
885 amino acids: PaperBLAST, CDD, Compare to cluster

ADH2_ENTHI / Q24803 Aldehyde-alcohol dehydrogenase 2; EC 1.1.1.1; EC 1.2.1.10 from Entamoeba histolytica
GB|AAA81906.1 aldehyde-alcohol dehydrogenase 2; EC 1.1.1.1; EC 1.2.1.10 from Entamoeba histolytica
PFams: Aldedh, Fe-ADH, Fe-ADH_2, Fe-ADH_2
870 amino acids: PaperBLAST, CDD, Compare to cluster

P33744 alcohol/aldehyde dehydrogenase (EC 1.1.1.1; EC 1.2.1.10; EC 1.2.1.57) from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
ADHE_CLOAB / P33744 Aldehyde-alcohol dehydrogenase; AAD; EC 1.1.1.1; EC 1.2.1.3 from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
GB|AAD04638.1 aldehyde-alcohol dehydrogenase; EC 1.1.1.1; EC 1.2.1.10 from Clostridium acetobutylicum ATCC 824
PFams: Aldedh, Fe-ADH
862 amino acids: PaperBLAST, CDD, Compare to cluster

b1241 aldehyde/alcohol dehydrogenase AdhE (EC 1.1.1.1; EC 1.2.1.10) from Escherichia coli K-12 substr. MG1655
P0A9Q7 aldehyde/alcohol dehydrogenase AdhE (EC 1.1.1.1; EC 1.2.1.10) from Escherichia coli (strain K12)
MB|P0A9Q7 aldehyde-alcohol dehydrogenase; EC 1.1.1.1; EC 1.2.1.10 from Escherichia coli K12
PFams: Aldedh, Fe-ADH, Fe-ADH_2
891 amino acids: PaperBLAST, CDD, Compare to cluster

A8JI07 alcohol dehydrogenase / acetaldehyde dehydrogenase (EC 1.2.1.10; EC 1.1.1.1) from Chlamydomonas reinhardtii
PFams: Aldedh, Fe-ADH, Fe-ADH_2
954 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 4 370-422 amino acids (not heteromeric)

ADH1_GEOTN / A4IP64 Long-chain-alcohol dehydrogenase 1; Alcohol dehydrogenase 1; ADH1; Fatty alcohol oxidoreductase 1; Glycerol dehydrogenase; EC 1.1.1.192; EC 1.1.1.6 from Geobacillus thermodenitrificans (strain NG80-2)
A4IP64 alcohol dehydrogenase (EC 1.1.1.1); long-chain-alcohol dehydrogenase (EC 1.1.1.192) from Geobacillus thermodenitrificans
PFams: Fe-ADH, Fe-ADH_2
395 amino acids: PaperBLAST, CDD, Compare to cluster

A0A1D3TV27 alcohol dehydrogenase (EC 1.1.1.1) from Anaerobium acetethylicum
PFams: Fe-ADH, Fe-ADH_2
373 amino acids: PaperBLAST, CDD, Compare to cluster

ADHA_THEET / Q9F282 Long-chain primary alcohol dehydrogenase AdhA; EC 1.1.1.2 from Thermoanaerobacter ethanolicus (Clostridium thermohydrosulfuricum)
B0K3U7 alcohol dehydrogenase (EC 1.1.1.1); alcohol dehydrogenase (NADP+) (EC 1.1.1.2) from Thermoanaerobacter sp.
PFams: Fe-ADH, Fe-ADH_2
399 amino acids: PaperBLAST, CDD, Compare to cluster

P0DJA2 ethanol dehydrogenase (EC 1.1.5.5) from Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4)
P0DJA2 alcohol dehydrogenase (EC 1.1.1.1) from Zymomonas mobilis subsp. mobilis
PFams: Fe-ADH, Fe-ADH_2
383 amino acids: PaperBLAST, CDD, Compare to cluster

ADH4_SCHPO / Q09669 Alcohol dehydrogenase 4; Alcohol dehydrogenase IV; EC 1.1.1.1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Q09669 alcohol dehydrogenase (EC 1.1.1.1) from Schizosaccharomyces pombe
RF|NP_592819.1 alcohol dehydrogenase Adh4; EC 1.1.1.1 from Schizosaccharomyces pombe
PFams: Fe-ADH, Fe-ADH_2
422 amino acids: PaperBLAST, CDD, Compare to cluster

P13604 NADPH-dependent butanol dehydrogenase (EC 1.1.1.2) from Clostridium saccharobutylicum
GB|AAA83520.1 NADPH-dependent butanol dehydrogenase; EC 1.1.1.1 from Clostridium saccharobutylicum
PFams: Fe-ADH, Fe-ADH_2
388 amino acids: PaperBLAST, CDD, Compare to cluster

P10127 alcohol dehydrogenase IV (EC 1.1.1.1; EC 1.1.1.190) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
ADH4_YEAST / P10127 Alcohol dehydrogenase 4; Alcohol dehydrogenase IV; ADHIV; EC 1.1.1.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: Fe-ADH, Fe-ADH_2
382 amino acids: PaperBLAST, CDD, Compare to cluster

P71017 choline dehydrogenase from Bacillus subtilis (strain 168)
GBSB_BACSU / P71017 Choline dehydrogenase; Alcohol dehydrogenase; EC 1.1.1.- from Bacillus subtilis (strain 168)
CH_005199 alcohol dehydrogenase; EC 1.1.1.1 from Bacillus subtilis
PFams: Fe-ADH, Fe-ADH_2
402 amino acids: PaperBLAST, CDD, Compare to cluster

Q9XDN0 propanol dehydrogenase (EC 1.1.1.1) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
PFams: Fe-ADH, Fe-ADH_2
370 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 5 345-384 amino acids (not heteromeric)

D4GP73 alcohol dehydrogenase [NAD(P)+] (EC 1.1.1.71) from Haloferax volcanii
PFams: ADH_N, ADH_zinc_N
349 amino acids: PaperBLAST, CDD, Compare to cluster

B0KBL1 alcohol dehydrogenase (EC 1.1.1.1) from Thermoanaerobacter pseudethanolicus
PFams: ADH_N, ADH_zinc_N
353 amino acids: PaperBLAST, CDD, Compare to cluster

Q5M4K4 alcohol dehydrogenase (EC 1.1.1.1) from Streptococcus thermophilus
PFams: ADH_N, ADH_zinc_N, ADH_zinc_N_2
345 amino acids: PaperBLAST, CDD, Compare to cluster

Q5V676 alcohol dehydrogenase [NAD(P)+] (EC 1.1.1.71) from Haloarcula marismortui
PFams: ADH_N, ADH_zinc_N
384 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 6 234-264 amino acids (not heteromeric)

Q4J9F2 alcohol dehydrogenase (EC 1.1.1.1) from Sulfolobus acidocaldarius
PFams: adh_short, KR, adh_short_C2
255 amino acids: PaperBLAST, CDD, Compare to cluster

C6A190 alcohol dehydrogenase (NADP+) (EC 1.1.1.2); alcohol dehydrogenase [NAD(P)+] (EC 1.1.1.71) from Thermococcus sibiricus
PFams: adh_short, KR, adh_short_C2
234 amino acids: PaperBLAST, CDD, Compare to cluster

Q4J702 alcohol dehydrogenase (EC 1.1.1.1) from Sulfolobus acidocaldarius
PFams: adh_short, KR, adh_short_C2
264 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 7 232-271 amino acids (not heteromeric)

OXI1_COCH4 / N4WE73 Dehydrogenase OXI1; T-toxin biosynthesis protein OXI1; EC 1.1.1.1 from Cochliobolus heterostrophus (strain C4 / ATCC 48331 / race T) (Southern corn leaf blight fungus) (Bipolaris maydis)
PFams: adh_short_C2, adh_short
232 amino acids: PaperBLAST, CDD, Compare to cluster

A0A075B5H4 alcohol dehydrogenase (EC 1.1.1.1) from Sphingomonas sp. A1
PFams: adh_short, KR, adh_short_C2
258 amino acids: PaperBLAST, CDD, Compare to cluster

ASQE_EMENI / Q5AR48 Short chain dehydrogenase asqE; 4'-methoxyviridicatin/aspoquinolone biosynthesis cluster protein asqE; Aspoquinolone biosynthesis protein E; EC 1.1.1.1 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans)
PFams: adh_short, KR, adh_short_C2
271 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 8 387-387 amino acids (not heteromeric)

ADH2_GEOTN / A4ISB9 Long-chain-alcohol dehydrogenase 2; Alcohol dehydrogenase 2; ADH2; Fatty alcohol oxidoreductase 2; EC 1.1.1.192 from Geobacillus thermodenitrificans (strain NG80-2)
A4ISB9 alcohol dehydrogenase (EC 1.1.1.1); long-chain-alcohol dehydrogenase (EC 1.1.1.192) from Geobacillus thermodenitrificans
PFams: Fe-ADH, Fe-ADH_2
387 amino acids: PaperBLAST, CDD, Compare to cluster

U6CL97 alcohol dehydrogenase (NADP+) (EC 1.1.1.2); alcohol dehydrogenase [NAD(P)+] (EC 1.1.1.71) from Pectobacterium atrosepticum
PFams: Fe-ADH, Fe-ADH_2
387 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 9 278-278 amino acids (not heteromeric)

Q5JI09 alcohol dehydrogenase (EC 1.1.1.1) from Thermococcus kodakarensis
PFams: Aldo_ket_red
278 amino acids: PaperBLAST, CDD, Compare to cluster

Q8TZM9 alcohol dehydrogenase (EC 1.1.1.1) from Pyrococcus furiosus
PFams: Aldo_ket_red
278 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 10 317-328 amino acids (not heteromeric)

Q9HIM3 alcohol dehydrogenase (EC 1.1.1.1) from Thermoplasma acidophilum
PFams: ADH_N, ADH_zinc_N
328 amino acids: PaperBLAST, CDD, Compare to cluster

Q6L0S1 alcohol dehydrogenase (EC 1.1.1.1) from Picrophilus torridus
PFams: ADH_N, ADH_zinc_N, ADH_zinc_N_2
317 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 11 254-256 amino acids (not heteromeric)

ADH_DROME / P00334 Alcohol dehydrogenase; EC 1.1.1.1 from Drosophila melanogaster (Fruit fly)
PFams: adh_short, KR, adh_short_C2
256 amino acids: PaperBLAST, CDD, Compare to cluster

ADH_DROLE / P10807 Alcohol dehydrogenase; EC 1.1.1.1 from Drosophila lebanonensis (Fruit fly) (Scaptodrosophila lebanonensis)
PFams: adh_short, KR, adh_short_C2
254 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/8 heteromeric)

Q1G151 alcohol dehydrogenase (EC 1.1.1.1) from Bombyx mori
PFams: adh_short, KR, 3Beta_HSD, Epimerase, adh_short_C2
274 amino acids: PaperBLAST, CDD

Q76HN6 alcohol dehydrogenase (EC 1.1.1.1) from Pseudomonas putida
PFams: GMC_oxred_N, Lycopene_cycl, GMC_oxred_C
526 amino acids: PaperBLAST, CDD

RDH14_HUMAN / Q9HBH5 Retinol dehydrogenase 14; Alcohol dehydrogenase PAN2; Short chain dehydrogenase/reductase family 7C member 4; EC 1.1.1.300 from Homo sapiens (Human)
Q9HBH5 NADP-retinol dehydrogenase (EC 1.1.1.300); alcohol dehydrogenase [NAD(P)+] (EC 1.1.1.71) from Homo sapiens
PFams: adh_short, KR, Epimerase, adh_short_C2
336 amino acids: PaperBLAST, CDD

DHS3_CAEEL / A5JYX5 Protein dhs-3; Alcohol dehydrogenase dhs-3; EC 1.1.1.1 from Caenorhabditis elegans
PFams: adh_short, KR, adh_short_C2
309 amino acids: PaperBLAST, CDD

RED2_COCH4 / N4WE43 Dehydrogenase RED2; T-toxin biosynthesis protein RED2; EC 1.1.1.1 from Cochliobolus heterostrophus (strain C4 / ATCC 48331 / race T) (Southern corn leaf blight fungus) (Bipolaris maydis)
PFams: adh_short, KR, adh_short_C2
265 amino acids: PaperBLAST, CDD

RED3_COCH4 / N4WW42 Dehydrogenase RED3; T-toxin biosynthesis protein RED3; EC 1.1.1.1 from Cochliobolus heterostrophus (strain C4 / ATCC 48331 / race T) (Southern corn leaf blight fungus) (Bipolaris maydis)
PFams: adh_short_C2, adh_short, KR
196 amino acids: PaperBLAST, CDD

ADH_CUPNH / Q0KDL6 Alcohol dehydrogenase; EC 1.1.1.1; EC 1.1.1.4; EC 1.2.1.3 from Cupriavidus necator (strain ATCC 17699 / H16 / DSM 428 / Stanier 337) (Ralstonia eutropha)
PFams: ADH_N, ADH_zinc_N, ADH_zinc_N_2
366 amino acids: PaperBLAST, CDD
(similar to BRENDA::B0KBL1 from Cluster 5, but similarity to seed sequence is below thresholds)

Q12177 NADH-dependent aldehyde reductase (EC 1.1.1.77; EC 1.1.1.244; EC 1.1.1.1) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
PFams: Epimerase, NmrA, GDP_Man_Dehyd, 3Beta_HSD, NAD_binding_10
298 amino acids: PaperBLAST, CDD