Clusters of Characterized Proteins

Clustering the characterized proteins for fucDH (2-keto-3-deoxy-L-fuconate 4-dehydrogenase) in L-fucose catabolism

Or see other characterized proteins similar to fucDH

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Definition of fucDH

• Curated sequence Q8P3K4: 2-keto-3-deoxy-L-fuconate dehydrogenase; EC 1.1.1.-
• UniProt sequence A0A4P7ABK7: SubName: Full=SDR family oxidoreductase {ECO:0000313|EMBL:QBP77113.1};
• UniProt sequence D8IS13: SubName: Full=Short-chain alcohol dehydrogenase protein {ECO:0000313|EMBL:ADJ65356.1};
• UniProt sequence B2T9V3: SubName: Full=Short-chain dehydrogenase/reductase SDR {ECO:0000313|EMBL:ACD21205.1};
• Comment: No EC number, but XCC4067 (Q8P3K4) is annotated in SwissProt based on PMID:17144652. C785_RS13675 (A0A4P7ABK7) was also shown to have this acivity (PMC6336799) HSERO_RS19365 (D8IS13) and BPHYT_RS34215 (B2T9V3) are important for fucose utilization (The substrate for EC 1.1.1.401 (2-dehydro-3-deoxy-L-rhamnonate 4-dehydrogenase) has the other stereochemistry at position 4.)

Fetched 4 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 4 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 247-300 amino acids (not heteromeric)

FUCDH_XANCP / Q8P3K4 2-keto-3-deoxy-L-fuconate dehydrogenase; EC 1.1.1.- from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25)
PFams: adh_short, adh_short_C2
300 amino acids: PaperBLAST, CDD, Compare to cluster

A0A4P7ABK7 SDR family oxidoreductase
254 amino acids: PaperBLAST, CDD, Compare to cluster

B2T9V3 Short-chain dehydrogenase/reductase SDR
247 amino acids: PaperBLAST, CDD, Compare to cluster

D8IS13 Short-chain alcohol dehydrogenase protein
254 amino acids: PaperBLAST, CDD, Compare to cluster