Clusters of Characterized Proteins

Clustering the characterized proteins for galP (galactose:H+ symporter GalP) in D-galactose catabolism

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Definition of galP

• Curated sequence P0AEP1: Galactose-proton symporter; Galactose transporter. Galactose:H+ symporter, GalP. Also transports glucose, xylose, fucose (6-deoxygalactose), 2-deoxygalactose and 2-deoxyglucose) (Henderson and Giddens 1977. ; galactose:H⁺ symporter. galactose:H⁺ symporter. galactose:H+ symporter (galP)
• Curated sequence CH_091493: sugar transport protein 6. Sugar transport protein 6; Hexose transporter 6. High affinity monosaccharide (KM ≈ 20 µM):H+ symporter, Stp6 (takes up glucose, 3-O-methylglucose, mannose, fructose, galactose and to a lesser extent, xylose and ribulose.
• Curated sequence P0AE24: Arabinose-proton symporter; Arabinose transporter. Arabinose (xylose; galactose):H+ symporter, AraE (low affinity high capacity). arabinose:H⁺ symporter. arabinose:H⁺ symporter
• Curated sequence P96710: Arabinose-proton symporter; Arabinose transporter. L-arabinose:proton symporter, AraE (Sa-Nogueira and Ramos, 1997). Also transports xylose, galactose and α-1,5 arabinobiose
• Curated sequence Q9LT15: The high affinity sugar:H+ symporter (sugar uptake) porter of 514 aas and 12 TMSs, STP10. It transports glucose, galactose and mannose, and is therefore a hexose transporter (Rottmann et al. 2016). The 2.4

Fetched 5 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 5 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 464-514 amino acids (not heteromeric)

b2943 galactose:H+ symporter (galP) from Escherichia coli BW25113
b2943 galactose:H⁺ symporter from Escherichia coli K-12 substr. MG1655
P0AEP1 galactose:H⁺ symporter from Escherichia coli (strain K12)
GALP_ECOLI / P0AEP1 Galactose-proton symporter; Galactose transporter from Escherichia coli (strain K12)
TC 2.A.1.1.1 / P0AEP1 Galactose:H+ symporter, GalP. Also transports glucose, xylose, fucose (6-deoxygalactose), 2-deoxygalactose and 2-deoxyglucose) (Henderson and Giddens 1977; from Escherichia coli (strain K12)
PFams: TRI12, Sugar_tr, MFS_1, MFS_2, MFS_1
464 amino acids: PaperBLAST, CDD, Compare to cluster

STP6_ARATH / Q9SFG0 Sugar transport protein 6; Hexose transporter 6 from Arabidopsis thaliana (Mouse-ear cress)
TC 2.A.1.1.56 / Q9SFG0 High affinity monosaccharide (KM ≈ 20 µM):H+ symporter, Stp6 (takes up glucose, 3-O-methylglucose, mannose, fructose, galactose and to a lesser extent, xylose and ribulose. from Arabidopsis thaliana (Mouse-ear cress)
RF|NP_187247.1 sugar transport protein 6 from Arabidopsis thaliana
PFams: Sugar_tr, MFS_1
507 amino acids: PaperBLAST, CDD, Compare to cluster

b2841 arabinose:H⁺ symporter from Escherichia coli K-12 substr. MG1655
P0AE24 arabinose:H⁺ symporter from Escherichia coli (strain K12)
ARAE_ECOLI / P0AE24 Arabinose-proton symporter; Arabinose transporter from Escherichia coli (strain K12)
TC 2.A.1.1.2 / P0AE24 Arabinose (xylose; galactose):H+ symporter, AraE (low affinity high capacity) from Escherichia coli
PFams: TRI12, Sugar_tr, MFS_1
472 amino acids: PaperBLAST, CDD, Compare to cluster

ARAE_BACSU / P96710 Arabinose-proton symporter; Arabinose transporter from Bacillus subtilis (strain 168)
TC 2.A.1.1.55 / P96710 L-arabinose:proton symporter, AraE (Sa-Nogueira and Ramos, 1997). Also transports xylose, galactose and α-1,5 arabinobiose from Bacillus subtilis
PFams: Sugar_tr, MFS_1, MFS_1
464 amino acids: PaperBLAST, CDD, Compare to cluster

TC 2.A.1.1.124 / Q9LT15 The high affinity sugar:H+ symporter (sugar uptake) porter of 514 aas and 12 TMSs, STP10. It transports glucose, galactose and mannose, and is therefore a hexose transporter (Rottmann et al. 2016). The 2.4 from Arabidopsis thaliana
PFams: MFS_1, Sugar_tr
514 amino acids: PaperBLAST, CDD, Compare to cluster