Clusters of Characterized Proteins

GapMind for catabolism of small carbon sources

Clusters of Characterized Proteins

Clustering the characterized proteins for kdgK (2-keto-3-deoxygluconate kinase) in D-galacturonate catabolism

Or see other characterized proteins similar to kdgK

Or see all steps for D-galacturonate catabolism

Or cluster curated proteins matching a keyword

Definition of kdgK

Curated proteins or TIGRFams with EC 2.7.1.45
Curated proteins or TIGRFams with EC 2.7.1.178
Ignore hits to Q9ZU29 when looking for 'other' hits (2-dehydro-3-deoxyglucono/galactono-kinase (EC 2.7.1.178))
Ignore hits to DEHYDDEOXGALACTKIN-MONOMER when looking for 'other' hits (2-dehydro-3-deoxygalactonokinase (EC 2.7.1.178; EC 2.7.1.58). 2-dehydro-3-deoxygalactonokinase (EC 2.7.1.178))
Comment: The entry for Q9ZU29 is erroneous (the correct accession is Q97U29). EcoCyc 2-dehydro-3-deoxygalactonokinase (dgoK) is given this EC number as well but I could not determine why. It doesn't link to the ketodeoxygluconate kinase reaction.

Fetched 14 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 12 of these sequences

Found 1 clusters of similar sequences. Another 3 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 309-339 amino acids (not heteromeric)

The first sequence in each cluster is the seed.

KDGK_THET8 / Q53W83 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
PFams: PfkB
309 amino acids: PaperBLAST, CDD, Compare to cluster

D4GR05 6-phosphofructokinase (EC 2.7.1.11); 2-dehydro-3-deoxyglucono/galactono-kinase (EC 2.7.1.178); 2-dehydro-3-deoxygalactonokinase (EC 2.7.1.58) from Haloferax volcanii
PFams: PfkB
318 amino acids: PaperBLAST, CDD, Compare to cluster

D4GSE6 2-dehydro-3-deoxyglucono/galactono-kinase (EC 2.7.1.178); 2-dehydro-3-deoxygluconokinase (EC 2.7.1.45) from Haloferax volcanii
PFams: PfkB
320 amino acids: PaperBLAST, CDD, Compare to cluster

Q96XN9 2-dehydro-3-deoxygluconokinase (EC 2.7.1.45) from Sulfurisphaera tokodaii
PFams: PfkB
311 amino acids: PaperBLAST, CDD, Compare to cluster

Q97U29 2-dehydro-3-deoxyglucono/2-dehydro-3-deoxygalactonokinase monomer (EC 2.7.1.178) from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
KDGK_SACS2 / Q97U29 2-dehydro-3-deoxygluconokinase/2-dehydro-3-deoxygalactonokinase; 2-dehydro-3-deoxyglucono/galactono-kinase; 2-keto-3-deoxy-galactonokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; KDGal kinase; EC 2.7.1.178 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus)
Q97U29 2-dehydro-3-deoxyglucono/galactono-kinase (EC 2.7.1.178) from Saccharolobus solfataricus
PFams: PfkB
313 amino acids: PaperBLAST, CDD, Compare to cluster

Q9WXS2 2-keto-3-deoxygluconate kinase (EC 2.7.1.178) from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
Q9WXS2 2-dehydro-3-deoxygluconokinase (EC 2.7.1.45) from Thermotoga maritima
PFams: PfkB
339 amino acids: PaperBLAST, CDD, Compare to cluster

KDGK_ECOLW / E0J5J4 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Escherichia coli (strain ATCC 9637 / CCM 2024 / DSM 1116 / NCIMB 8666 / NRRL B-766 / W)
PFams: PfkB
309 amino acids: PaperBLAST, CDD, Compare to cluster

b3526 2-dehydro-3-deoxygluconokinase (EC 2.7.1.178; EC 2.7.1.45) from Escherichia coli K-12 substr. MG1655
P37647 2-dehydro-3-deoxygluconokinase (EC 2.7.1.178) from Escherichia coli (strain K12)
KDGK_ECOLI / P37647 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Escherichia coli (strain K12)
PFams: PfkB
309 amino acids: PaperBLAST, CDD, Compare to cluster

KDGK_BACSU / P50845 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Bacillus subtilis (strain 168)
PFams: PfkB
324 amino acids: PaperBLAST, CDD, Compare to cluster

KDGK_THETE / Q704D0 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Thermoproteus tenax
PFams: PfkB
325 amino acids: PaperBLAST, CDD, Compare to cluster

RR42_RS28860 2-dehydro-3-deoxygluconokinase (EC 2.7.1.45) from Cupriavidus basilensis 4G11
PFams: PfkB
311 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/3 heteromeric)

P45416 2-dehydro-3-deoxy-D-gluconate kinase (EC 2.7.1.178) from Dickeya dadantii (strain 3937)
KDGK_DICD3 / P45416 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxygluconokinase; 3-deoxy-2-oxo-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937))
PFams: PfkB
310 amino acids: PaperBLAST, CDD
(similar to SwissProt::E0J5J4 from Cluster 1, but similarity to seed sequence is below thresholds)

KDGK_THEAC / Q9HLV3 2-dehydro-3-deoxygluconokinase; 2-keto-3-deoxy-D-gluconate kinase; KDG kinase; EC 2.7.1.45 from Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
PFams: BcrAD_BadFG
336 amino acids: PaperBLAST, CDD

CA265_RS19865 2-dehydro-3-deoxygluconate kinase (EC 2.7.1.45) from Pedobacter sp. GW460-11-11-14-LB5
PFams: PfkB
351 amino acids: PaperBLAST, CDD