Clusters of Characterized Proteins

Clustering the characterized proteins for uxuL (D-galactaro-1,5-lactonase (UxuL or UxuF)) in D-galacturonate catabolism

Or see other characterized proteins similar to uxuL

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Definition of uxuL

• UniProt sequence B2UIY8: SubName: Full=SMP-30/Gluconolaconase/LRE domain protein {ECO:0000313|EMBL:ACD29539.1};
• UniProt sequence Q888H2: SubName: Full=Senescence marker protein-30 family protein {ECO:0000313|EMBL:AAO54583.1};
• UniProt sequence A4JG52: SubName: Full=3-carboxymuconate cyclase-like protein {ECO:0000313|EMBL:ABO55255.1};
• UniProt sequence A0A0H3KPX2: SubName: Full=6-phosphogluconolactonase {ECO:0000313|EMBL:BAG44069.1}; EC=3.1.1.31 {ECO:0000313|EMBL:BAG44069.1};
• UniProt sequence Q39EM3: SubName: Full=3-carboxymuconate cyclase-like protein {ECO:0000313|EMBL:ABB09093.1};
• UniProt sequence Q881W7: SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AAO56265.1};
• Curated sequence GFF3393: galactaro-1,5-lactonase
• Curated sequence HSERO_RS15795: galactaro-1,5-lactonase
• Comment: Two families of D-galactaro-1,5-lactonase were described, uxuL and uxuF. All of these proteins are active on D-glucaro-1,5-lactone as well, although PSPTO_2765 is much more active on galactaro,1-5-lactone. UxuL = Rpic_4446 PSPTO_1052 UxuF = Bcep1808_2255 BMULJ_02167 Bcep18194_A5499 PSPTO_2765 PS417_17365 (GFF3393) and HSERO_RS15795 were inferred from mutant phenotype

Fetched 8 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 8 of these sequences

Found 2 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 348-359 amino acids (not heteromeric)

A0A0H3KPX2 6-phosphogluconolactonase; EC=3.1.1.31
348 amino acids: PaperBLAST, CDD, Compare to cluster

A4JG52 3-carboxymuconate cyclase-like protein
349 amino acids: PaperBLAST, CDD, Compare to cluster

Q39EM3 3-carboxymuconate cyclase-like protein
349 amino acids: PaperBLAST, CDD, Compare to cluster

Q881W7 Uncharacterized protein
359 amino acids: PaperBLAST, CDD, Compare to cluster

HSERO_RS15795 galactaro-1,5-lactonase from Herbaspirillum seropedicae SmR1
PFams: Lactonase
352 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 291-300 amino acids (not heteromeric)

B2UIY8 SMP-30/Gluconolaconase/LRE domain protein
300 amino acids: PaperBLAST, CDD, Compare to cluster

Q888H2 Senescence marker protein-30 family protein
294 amino acids: PaperBLAST, CDD, Compare to cluster

PS417_17365 galactaro-1,5-lactonase from Pseudomonas simiae WCS417
PFams: SGL
291 amino acids: PaperBLAST, CDD, Compare to cluster