Clusters of Characterized Proteins

Clustering the characterized proteins for gamP (glucosamine PTS system, EII-CBA components (GamP/NagE)) in D-glucosamine (chitosamine) catabolism

Or see other characterized proteins similar to gamP

Or see all steps for D-glucosamine (chitosamine) catabolism

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Definition of gamP

• Curated sequence P09323: protein-Npi-phosphohistidine-N-acetyl-D-glucosamine phosphotransferase (EC 2.7.1.193). PTS system N-acetylglucosamine-specific EIICBA component; EIICBA-Nag; EII-Nag; EC 2.7.1.193. N-Acetyl glucosamine (NAG) porter (NagE). N-acetylglucosamine-specific PTS enzyme IIABC component (EC 2.7.1.193; EC 2.7.1.191). N-acetylglucosamine-specific PTS enzyme IIABC component (EC 2.7.1.193; EC 2.7.1.191)
• Curated sequence P39816: Putative PTS system glucosamine-specific EIICBA component; EC 2.7.1.193. The glucosamine IICBA porter (GamP) (40% identical to 4.A.1.1.2) (Plumbridge 2015). The IIA domain in this protein can transfer the phosphoryl moiety to the maltose, N-acetylglucosamine, sucrose and trehalose PTS systems (MalP, NagP, SacP and TreP, respectively)
• Ignore hits to P45604 when looking for 'other' hits (protein-Npi-phosphohistidine-N-acetyl-D-glucosamine phosphotransferase (EC 2.7.1.193))
• Comment: Unified EII-CBA systems from E. coli ("nagE") or B. subtilis ("gamP"). Ignore a close homolog of NagE from Klebsiella, annotated as a NAG PTS system, which is not well studied and may well act on glucosamine as well.

Fetched 2 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 2 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 631-648 amino acids (not heteromeric)

b0679 N-acetylglucosamine-specific PTS enzyme IIABC component (EC 2.7.1.193; EC 2.7.1.191) from Escherichia coli K-12 substr. MG1655
P09323 N-acetylglucosamine-specific PTS enzyme IIABC component (EC 2.7.1.193; EC 2.7.1.191) from Escherichia coli (strain K12)
PTW3C_ECOLI / P09323 PTS system N-acetylglucosamine-specific EIICBA component; EIICBA-Nag; EII-Nag; EC 2.7.1.193 from Escherichia coli (strain K12)
P09323 protein-Npi-phosphohistidine-N-acetyl-D-glucosamine phosphotransferase (EC 2.7.1.193) from Escherichia coli
TC 4.A.1.1.2 / P09323 N-Acetyl glucosamine (NAG) porter (NagE) from Escherichia coli
PFams: PTS_EIIC, PTS_EIIB, PTS_EIIA_1
648 amino acids: PaperBLAST, CDD, Compare to cluster

PTW3C_BACSU / P39816 Putative PTS system glucosamine-specific EIICBA component; EC 2.7.1.193 from Bacillus subtilis (strain 168)
TC 4.A.1.1.6 / P39816 The glucosamine IICBA porter (GamP) (40% identical to 4.A.1.1.2) (Plumbridge 2015). The IIA domain in this protein can transfer the phosphoryl moiety to the maltose, N-acetylglucosamine, sucrose and trehalose PTS systems (MalP, NagP, SacP and TreP, respectively) from Bacillus subtilis
PFams: PTS_EIIC, PTS_EIIB, PTS_EIIA_1
631 amino acids: PaperBLAST, CDD, Compare to cluster