Clusters of Characterized Proteins

GapMind for catabolism of small carbon sources

Clusters of Characterized Proteins

Clustering the characterized proteins for glk (glucokinase) in D-glucose catabolism

Or see other characterized proteins similar to glk

Or see all steps for D-glucose catabolism

Or cluster curated proteins matching a keyword

Definition of glk

Curated proteins or TIGRFams with EC 2.7.1.1
Curated proteins or TIGRFams with EC 2.7.1.2
UniProt sequence A8LLL9: SubName: Full=Glucokinase {ECO:0000313|EMBL:ABV93397.1}; EC=2.7.1.2 {ECO:0000313|EMBL:ABV93397.1};
UniProt sequence Q5GAN8: SubName: Full=General specificity hexokinase {ECO:0000313|EMBL:AAT74901.1};
Curated sequence MONOMER-19002: N-acetylglucosamine kinase (EC 2.7.1.59)
Ignore hits to CH_123431 when looking for 'other' hits (N-acetylglucosamine kinase)
Ignore hits to Q9ADE8 when looking for 'other' hits (polyphosphate-glucose phosphotransferase (EC 2.7.1.63))
UniProt sequence I7DXX1: SubName: Full=Glucokinase Glk {ECO:0000313|EMBL:AFO90274.1}; EC=2.7.1.2 {ECO:0000313|EMBL:AFO90274.1};
Comment: Dshi_1655 (A8LLL9) was identified using fitness data, is very important for growth on glucose and several glucose-containing disaccharides; and functional residues seem to be conserved. The related protein PGA1_c05420 (I7DXX1) also seems to be glk. Q5GAN8 = hexA from B. fragilis is a broad-specificity hexokinase (PMID:15659667). Q5GBH5 = rokA = MONOMER-19002 from B. fragilis is a glucose/mannose/NAG kinase (PMID:15659667). (MetaCyc lists it as NAG kinase only but it is just as active on glucose.) CH_123431 is nearly identical to a characterized broad-specificity hexose kinase, so ignore. SCO5059 (Q9ADE8) is reported to have ATP-glucokinase activity (PMID:24200789), so ignore.

Fetched 98 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 91 of these sequences

Found 4 clusters of similar sequences. Another 8 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 445-572 amino acids (not heteromeric)

A9SJG4 hexokinase (EC 2.7.1.1) from Physcomitrella patens
PFams: Hexokinase_1, Hexokinase_2
522 amino acids: PaperBLAST, CDD, Compare to cluster

A0A0P0I1H5 hexokinase (EC 2.7.1.1) from Helicoverpa armigera
PFams: Hexokinase_1, Hexokinase_2
450 amino acids: PaperBLAST, CDD, Compare to cluster

A0A172WCE4 hexokinase (EC 2.7.1.1) from Eimeria tenella
PFams: Hexokinase_1, Hexokinase_2
468 amino acids: PaperBLAST, CDD, Compare to cluster

A1Z0M6 glucokinase (EC 2.7.1.2) from Botrytis cinerea
PFams: Hexokinase_1, Hexokinase_2
559 amino acids: PaperBLAST, CDD, Compare to cluster

A1Z0M7 hexokinase (EC 2.7.1.1) from Botrytis cinerea
PFams: Hexokinase_1, Hexokinase_2
491 amino acids: PaperBLAST, CDD, Compare to cluster

A3EYB3 glucokinase (EC 2.7.1.2) from Felis catus
PFams: Hexokinase_1, Hexokinase_2
465 amino acids: PaperBLAST, CDD, Compare to cluster

A9RIW3 hexokinase (EC 2.7.1.1) from Physcomitrella patens
PFams: Hexokinase_1, Hexokinase_2
521 amino acids: PaperBLAST, CDD, Compare to cluster

A9S3H4 hexokinase (EC 2.7.1.1) from Physcomitrella patens
PFams: Hexokinase_1, Hexokinase_2
489 amino acids: PaperBLAST, CDD, Compare to cluster

A9S9F8 hexokinase (EC 2.7.1.1) from Physcomitrella patens
PFams: Hexokinase_1, Hexokinase_2
522 amino acids: PaperBLAST, CDD, Compare to cluster

A9SV13 hexokinase (EC 2.7.1.1) from Physcomitrella patens
PFams: Hexokinase_1, Hexokinase_2
520 amino acids: PaperBLAST, CDD, Compare to cluster

A9TDS4 hexokinase (EC 2.7.1.1) from Physcomitrella patens
PFams: Hexokinase_1, Hexokinase_2
518 amino acids: PaperBLAST, CDD, Compare to cluster

A9TLJ2 hexokinase (EC 2.7.1.1) from Physcomitrella patens
PFams: Hexokinase_1, Hexokinase_2
517 amino acids: PaperBLAST, CDD, Compare to cluster

A9U0F4 hexokinase (EC 2.7.1.1) from Physcomitrella patens
PFams: Hexokinase_1, Hexokinase_2
517 amino acids: PaperBLAST, CDD, Compare to cluster

A9U189 hexokinase (EC 2.7.1.1) from Physcomitrella patens
PFams: Hexokinase_1, Hexokinase_2
521 amino acids: PaperBLAST, CDD, Compare to cluster

B8K2W7 hexokinase (EC 2.7.1.1) from Helianthus annuus
PFams: Hexokinase_1, Hexokinase_2
498 amino acids: PaperBLAST, CDD, Compare to cluster

O74996 hexokinase (EC 2.7.1.1) from Yarrowia lipolytica
PFams: Hexokinase_1, Hexokinase_2
534 amino acids: PaperBLAST, CDD, Compare to cluster

HXKA_YEAST / P04806 Hexokinase-1; Hexokinase PI; Hexokinase-A; EC 2.7.1.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
P04806 hexokinase (EC 2.7.1.1) from Saccharomyces cerevisiae
PFams: Hexokinase_1, Hexokinase_2
485 amino acids: PaperBLAST, CDD, Compare to cluster

HXKB_YEAST / P04807 Hexokinase-2; Hexokinase PII; Hexokinase-B; EC 2.7.1.1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
P04807 hexokinase (EC 2.7.1.1) from Saccharomyces cerevisiae
PFams: Hexokinase_1, Hexokinase_2
486 amino acids: PaperBLAST, CDD, Compare to cluster

P35557 glucokinase (EC 2.7.1.1) from Homo sapiens
HXK4_HUMAN / P35557 Hexokinase-4; HK4; Glucokinase; Hexokinase type IV; HK IV; Hexokinase-D; EC 2.7.1.1 from Homo sapiens (Human)
P35557 hexokinase (EC 2.7.1.1); glucokinase (EC 2.7.1.2) from Homo sapiens
Q53Y25 glucokinase (EC 2.7.1.2) from Homo sapiens
PFams: Hexokinase_1, Hexokinase_2
465 amino acids: PaperBLAST, CDD, Compare to cluster

HXK2_SCHPO / P50521 Hexokinase-2; EC 2.7.1.1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
P50521 hexokinase (EC 2.7.1.1) from Schizosaccharomyces pombe
RF|NP_593865.1 hexokinase 2; EC 2.7.1.1; EC 2.7.1.2; EC 2.7.1.4; EC 2.7.1.7 from Schizosaccharomyces pombe
PFams: Hexokinase_1, Hexokinase_2
455 amino acids: PaperBLAST, CDD, Compare to cluster

Q02155 hexokinase (EC 2.7.1.1) from Plasmodium falciparum
PFams: Hexokinase_1, Hexokinase_2
493 amino acids: PaperBLAST, CDD, Compare to cluster

HXK1_SCHPO / Q09756 Hexokinase-1; EC 2.7.1.1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Q09756 hexokinase (EC 2.7.1.1) from Schizosaccharomyces pombe
RF|NP_592948.1 hexokinase 1; EC 2.7.1.1; EC 2.7.1.2; EC 2.7.1.4; EC 2.7.1.7 from Schizosaccharomyces pombe
PFams: Hexokinase_1, Hexokinase_2
484 amino acids: PaperBLAST, CDD, Compare to cluster

HXK7_ORYSJ / Q1WM16 Hexokinase-7; Hexokinase-6; EC 2.7.1.1 from Oryza sativa subsp. japonica (Rice)
Q1WM16 hexokinase (EC 2.7.1.1) from Oryza sativa Japonica Group
PFams: Hexokinase_1, Hexokinase_2
463 amino acids: PaperBLAST, CDD, Compare to cluster

Q42525 fructokinase (EC 2.7.1.4; EC 2.7.1.1) from Arabidopsis thaliana
HXK1_ARATH / Q42525 Hexokinase-1; Protein GLUCOSE INSENSITIVE 2; EC 2.7.1.1 from Arabidopsis thaliana (Mouse-ear cress)
Q42525 hexokinase (EC 2.7.1.1) from Arabidopsis thaliana
PFams: Hexokinase_1, Hexokinase_2
496 amino acids: PaperBLAST, CDD, Compare to cluster

Q5CWT5 hexokinase (EC 2.7.1.1) from Cryptosporidium parvum
PFams: Hexokinase_1, Hexokinase_2
518 amino acids: PaperBLAST, CDD, Compare to cluster

HXK5_ORYSJ / Q5W676 Hexokinase-5; Hexokinase I; EC 2.7.1.1 from Oryza sativa subsp. japonica (Rice)
Q5W676 hexokinase (EC 2.7.1.1) from Oryza sativa
PFams: Hexokinase_1, Hexokinase_2
507 amino acids: PaperBLAST, CDD, Compare to cluster

Q6X271 hexokinase (EC 2.7.1.1) from Physcomitrella patens
PFams: Hexokinase_1, Hexokinase_2
513 amino acids: PaperBLAST, CDD, Compare to cluster

HXK1_ORYSJ / Q8LH82 Hexokinase-1; EC 2.7.1.1 from Oryza sativa subsp. japonica (Rice)
Q8LH82 hexokinase (EC 2.7.1.1) from Oryza sativa
PFams: Hexokinase_1, Hexokinase_2
498 amino acids: PaperBLAST, CDD, Compare to cluster

Q8ST54 hexokinase (EC 2.7.1.1) from Trypanosoma cruzi
PFams: Hexokinase_1, Hexokinase_2
471 amino acids: PaperBLAST, CDD, Compare to cluster

Q96VP5 hexokinase (EC 2.7.1.1) from Ogataea angusta
PFams: Hexokinase_1, Hexokinase_2
471 amino acids: PaperBLAST, CDD, Compare to cluster

V5KAK3 hexokinase (EC 2.7.1.1) from Branchiostoma japonicum
PFams: Hexokinase_1, Hexokinase_2
458 amino acids: PaperBLAST, CDD, Compare to cluster

CH_024045 hexokinase 1; EC 2.7.1.1 from Entamoeba histolytica
GI|1070151 hexokinase 1; EC 2.7.1.1 from Entamoeba histolytica
PFams: Hexokinase_1, Hexokinase_2
445 amino acids: PaperBLAST, CDD, Compare to cluster

CH_024046 hexokinase 2; EC 2.7.1.1 from Entamoeba histolytica
GI|1070153 hexokinase 2; EC 2.7.1.1 from Entamoeba histolytica
PFams: Hexokinase_1, Hexokinase_2
445 amino acids: PaperBLAST, CDD, Compare to cluster

GI|134057515 hexokinase; EC 2.7.1.1 from Aspergillus niger
PFams: Hexokinase_1, Hexokinase_2
490 amino acids: PaperBLAST, CDD, Compare to cluster

CH_122617 hexokinase; EC 2.7.1.1 from Emericella nidulans
PFams: Hexokinase_1, Hexokinase_2
490 amino acids: PaperBLAST, CDD, Compare to cluster

HXK_BRUMA / A0A0K0JFP3 Hexokinase; BmHK; EC 2.7.1.1 from Brugia malayi (Filarial nematode worm)
PFams: Hexokinase_1, Hexokinase_2
572 amino acids: PaperBLAST, CDD, Compare to cluster

HXK1_SOLTU / O64390 Hexokinase-1; StHK1; EC 2.7.1.1 from Solanum tuberosum (Potato)
O64390 hexokinase (EC 2.7.1.1) from Solanum tuberosum
PFams: Hexokinase_1, Hexokinase_2
498 amino acids: PaperBLAST, CDD, Compare to cluster

P17709 glucokinase (EC 2.7.1.1) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
HXKG_YEAST / P17709 Glucokinase-1; Glucose kinase 1; GLK-1; EC 2.7.1.2 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: Hexokinase_1, Hexokinase_2
500 amino acids: PaperBLAST, CDD, Compare to cluster

HXK4_RAT / P17712 Hexokinase-4; HK4; Glucokinase; Hexokinase type IV; HK IV; Hexokinase-D; EC 2.7.1.1 from Rattus norvegicus (Rat)
P17712 glucokinase (EC 2.7.1.2) from Rattus norvegicus
PFams: Hexokinase_1, Hexokinase_2
465 amino acids: PaperBLAST, CDD, Compare to cluster

HXK_KLULA / P33284 Hexokinase; EC 2.7.1.1 from Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
P33284 hexokinase (EC 2.7.1.1) from Kluyveromyces lactis
PFams: Hexokinase_1, Hexokinase_2
485 amino acids: PaperBLAST, CDD, Compare to cluster

HXK4_MOUSE / P52792 Hexokinase-4; HK4; Glucokinase; Hexokinase type IV; HK IV; Hexokinase-D; EC 2.7.1.1 from Mus musculus (Mouse)
PFams: Hexokinase_1, Hexokinase_2
465 amino acids: PaperBLAST, CDD, Compare to cluster

HXKB_CANAL / P83776 Hexokinase-2; Cytoplasmic antigenic protein 3; Hexokinase PII; Hexokinase-B; EC 2.7.1.1 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
PFams: Hexokinase_1, Hexokinase_2
484 amino acids: PaperBLAST, CDD, Compare to cluster

P93834 hexokinase (EC 2.7.1.1) from Arabidopsis thaliana
HXK2_ARATH / P93834 Hexokinase-2; EC 2.7.1.1 from Arabidopsis thaliana (Mouse-ear cress)
PFams: Hexokinase_1, Hexokinase_2
502 amino acids: PaperBLAST, CDD, Compare to cluster

EMI2_YEAST / Q04409 Putative glucokinase-2; Early meiotic induction protein 2; Glucose kinase 2; GLK-2; EC 2.7.1.2 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: Hexokinase_1, Hexokinase_2
500 amino acids: PaperBLAST, CDD, Compare to cluster

HXK8_ORYSJ / Q1WM15 Hexokinase-8; Hexokinase-4; EC 2.7.1.1 from Oryza sativa subsp. japonica (Rice)
PFams: Hexokinase_1, Hexokinase_2
458 amino acids: PaperBLAST, CDD, Compare to cluster

HXK_SCHMA / Q26609 Hexokinase; EC 2.7.1.1 from Schistosoma mansoni (Blood fluke)
PFams: Hexokinase_1, Hexokinase_2
451 amino acids: PaperBLAST, CDD, Compare to cluster

HXK3_ORYSJ / Q2KNB4 Hexokinase-3; Hexokinase-8; EC 2.7.1.1 from Oryza sativa subsp. japonica (Rice)
PFams: Hexokinase_1, Hexokinase_2
500 amino acids: PaperBLAST, CDD, Compare to cluster

HXK10_ORYSJ / Q2KNB5 Hexokinase-10; Hexokinase-7; EC 2.7.1.1 from Oryza sativa subsp. japonica (Rice)
Q2KNB5 hexokinase (EC 2.7.1.1) from Oryza sativa
PFams: Hexokinase_1, Hexokinase_2
504 amino acids: PaperBLAST, CDD, Compare to cluster

HXK9_ORYSJ / Q2KNB7 Hexokinase-9; Hexokinase-5; EC 2.7.1.1 from Oryza sativa subsp. japonica (Rice)
PFams: Hexokinase_1, Hexokinase_2
502 amino acids: PaperBLAST, CDD, Compare to cluster

HXK2_ORYSJ / Q2KNB9 Hexokinase-2; Hexokinase-3; EC 2.7.1.1 from Oryza sativa subsp. japonica (Rice)
Q2KNB9 hexokinase (EC 2.7.1.1) from Oryza sativa
PFams: Hexokinase_1, Hexokinase_2
494 amino acids: PaperBLAST, CDD, Compare to cluster

HXK4_ARATH / Q56XE8 Hexokinase-4; EC 2.7.1.1 from Arabidopsis thaliana (Mouse-ear cress)
PFams: Hexokinase_1, Hexokinase_2
502 amino acids: PaperBLAST, CDD, Compare to cluster

HXKG_KLULA / Q6CUZ3 Glucokinase-1; Glucose kinase 1; GLK-1; Hexokinase GLK1; EC 2.7.1.2; EC 2.7.1.1 from Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
PFams: Hexokinase_1, Hexokinase_2
481 amino acids: PaperBLAST, CDD, Compare to cluster

Q6Q8A5 hexokinase (EC 2.7.1.1; EC 2.7.1.4; EC 2.7.1.7) from Nicotiana tabacum
HXK2_TOBAC / Q6Q8A5 Hexokinase-2, chloroplastic; NtHxK2; EC 2.7.1.1 from Nicotiana tabacum (Common tobacco)
Q6Q8A5 hexokinase (EC 2.7.1.1) from Nicotiana tabacum
PFams: Hexokinase_1, Hexokinase_2
499 amino acids: PaperBLAST, CDD, Compare to cluster

HXK4_ORYSJ / Q6Z398 Hexokinase-4, chloroplastic; Hexokinase II; EC 2.7.1.1 from Oryza sativa subsp. japonica (Rice)
Q6Z398 hexokinase (EC 2.7.1.1) from Oryza sativa
PFams: Hexokinase_1, Hexokinase_2
509 amino acids: PaperBLAST, CDD, Compare to cluster

HXK6_ORYSJ / Q8LQ68 Hexokinase-6; Hexokinase-2; EC 2.7.1.1 from Oryza sativa subsp. japonica (Rice)
PFams: Hexokinase_1, Hexokinase_2
506 amino acids: PaperBLAST, CDD, Compare to cluster

HXKG_ASPNG / Q92407 Glucokinase; Glucose kinase; GLK; Hexokinase glkA; EC 2.7.1.2; EC 2.7.1.1 from Aspergillus niger
PFams: Hexokinase_1, Hexokinase_2
495 amino acids: PaperBLAST, CDD, Compare to cluster

HXK3_ARATH / Q9LPS1 Hexokinase-3; EC 2.7.1.1 from Arabidopsis thaliana (Mouse-ear cress)
PFams: Hexokinase_1, Hexokinase_2
498 amino acids: PaperBLAST, CDD, Compare to cluster

HXK1_SPIOL / Q9SEK3 Hexokinase-1; SoHxK1; EC 2.7.1.1 from Spinacia oleracea (Spinach)
Q9SEK3 hexokinase (EC 2.7.1.1) from Spinacia oleracea
PFams: Hexokinase_1, Hexokinase_2
498 amino acids: PaperBLAST, CDD, Compare to cluster

HXK2_SOLTU / Q9SQ76 Hexokinase-2; StHK2; EC 2.7.1.1 from Solanum tuberosum (Potato)
Q9SQ76 hexokinase (EC 2.7.1.1) from Solanum tuberosum
PFams: Hexokinase_1, Hexokinase_2
496 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 296-326 amino acids (not heteromeric)

Q5RLG0 hexokinase (EC 2.7.1.1) from Thermus caldophilus
PFams: ROK
302 amino acids: PaperBLAST, CDD, Compare to cluster

B1VZT1 glucokinase (EC 2.7.1.2) from Streptomyces griseus
PFams: ROK, Glucokinase
313 amino acids: PaperBLAST, CDD, Compare to cluster

P0A4E1 glucokinase (EC 2.7.1.2) from Streptomyces coelicolor
CH_017149 glucokinase; EC 2.7.1.2 from Streptomyces coelicolor
PFams: ROK, Glucokinase
317 amino acids: PaperBLAST, CDD, Compare to cluster

P54495 glucokinase (EC 2.7.1.1) from Bacillus subtilis (strain 168)
P54495 glucokinase (EC 2.7.1.2) from Bacillus subtilis
PFams: ROK
321 amino acids: PaperBLAST, CDD, Compare to cluster

Q5SLJ4 hexokinase (EC 2.7.1.1) from Thermus thermophilus
PFams: ROK
302 amino acids: PaperBLAST, CDD, Compare to cluster

Q7ZAH1 hexokinase (EC 2.7.1.1) from Thermoproteus tenax
PFams: ROK
301 amino acids: PaperBLAST, CDD, Compare to cluster

Q8RDE9 glucokinase (EC 2.7.1.2) from Caldanaerobacter subterraneus subsp. tengcongensis
PFams: ROK
315 amino acids: PaperBLAST, CDD, Compare to cluster

GI|1303865 glucokinase; EC 2.7.1.2 from Bacillus subtilis
PFams: ROK
321 amino acids: PaperBLAST, CDD, Compare to cluster

O31392 glucokinase (EC 2.7.1.2) from Bacillus megaterium
CH_014478 glucokinase; EC 2.7.1.2 from Bacillus megaterium
PFams: ROK
324 amino acids: PaperBLAST, CDD, Compare to cluster

GLK_PYRCJ / A3MUZ0 Glucokinase; ATP-dependent glucokinase; ATP-GLK; Glucose kinase; EC 2.7.1.2 from Pyrobaculum calidifontis (strain JCM 11548 / VA1)
PFams: ROK
296 amino acids: PaperBLAST, CDD, Compare to cluster

Q9X1I0 glucokinase subunit (EC 2.7.1.1) from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
GLK_THEMA / Q9X1I0 Glucokinase; ATP-dependent glucokinase; ATP-GLK; Glucose kinase; EC 2.7.1.2 from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
PFams: ROK
317 amino acids: PaperBLAST, CDD, Compare to cluster

GLK_AERPE / Q9YA47 Glucokinase; ATP-dependent glucokinase; ATP-GLK; Glucose kinase; EC 2.7.1.2 from Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1)
PFams: ROK
320 amino acids: PaperBLAST, CDD, Compare to cluster

Q5GBH5 N-acetylglucosamine kinase (EC 2.7.1.59) from Bacteroides fragilis
PFams: ROK
326 amino acids: PaperBLAST, CDD, Compare to cluster

Q8DVE8 glucokinase subunit (EC 2.7.1.1) from Streptococcus mutans serotype c (strain ATCC 700610 / UA159)
PFams: ROK
323 amino acids: PaperBLAST, CDD, Compare to cluster

Sama_1405 glucokinase (EC 2.7.1.2) from Shewanella amazonensis SB2B
PFams: ROK, Glucokinase
310 amino acids: PaperBLAST, CDD, Compare to cluster

Sama_2231 glucokinase (EC 2.7.1.2) from Shewanella amazonensis SB2B
PFams: ROK, Glucokinase
299 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 3 915-974 amino acids (not heteromeric)

HXK1_RAT / P05708 Hexokinase-1; Brain form hexokinase; Hexokinase type I; HK I; Hexokinase-A; EC 2.7.1.1 from Rattus norvegicus (Rat)
P05708 hexokinase (EC 2.7.1.1) from Rattus norvegicus
PFams: Hexokinase_1, Hexokinase_2, Hexokinase_1, Hexokinase_2
918 amino acids: PaperBLAST, CDD, Compare to cluster

P19367 hexokinase-1 (EC 2.7.1.1) from Homo sapiens
HXK1_HUMAN / P19367 Hexokinase-1; Brain form hexokinase; Hexokinase type I; HK I; Hexokinase-A; EC 2.7.1.1 from Homo sapiens (Human)
P19367 hexokinase (EC 2.7.1.1) from Homo sapiens
PFams: Hexokinase_1, Hexokinase_2, Hexokinase_1, Hexokinase_2
917 amino acids: PaperBLAST, CDD, Compare to cluster

HXK2_RAT / P27881 Hexokinase-2; Hexokinase type II; HK II; Hexokinase-B; EC 2.7.1.1 from Rattus norvegicus (Rat)
P27881 hexokinase (EC 2.7.1.1) from Rattus norvegicus
PFams: Hexokinase_1, Hexokinase_2, Hexokinase_1, Hexokinase_2
917 amino acids: PaperBLAST, CDD, Compare to cluster

P52789 hexokinase-2 (EC 2.7.1.1) from Homo sapiens
HXK2_HUMAN / P52789 Hexokinase-2; Hexokinase type II; HK II; Hexokinase-B; Muscle form hexokinase; EC 2.7.1.1 from Homo sapiens (Human)
P52789 hexokinase (EC 2.7.1.1); glucokinase (EC 2.7.1.2) from Homo sapiens
PFams: Hexokinase_1, Hexokinase_2, Hexokinase_1, Hexokinase_2
917 amino acids: PaperBLAST, CDD, Compare to cluster

Q5W5U3 hexokinase (EC 2.7.1.1) from Bos taurus
PFams: Hexokinase_1, Hexokinase_2, Hexokinase_1, Hexokinase_2
917 amino acids: PaperBLAST, CDD, Compare to cluster

HXK2_MOUSE / O08528 Hexokinase-2; Hexokinase type II; HK II; EC 2.7.1.1 from Mus musculus (Mouse)
PFams: Hexokinase_1, Hexokinase_2, Hexokinase_1, Hexokinase_2
917 amino acids: PaperBLAST, CDD, Compare to cluster

HXK1_MOUSE / P17710 Hexokinase-1; Hexokinase type I; HK I; Hexokinase, tumor isozyme; EC 2.7.1.1 from Mus musculus (Mouse)
PFams: Hexokinase_1, Hexokinase_2, Hexokinase_1, Hexokinase_2
974 amino acids: PaperBLAST, CDD, Compare to cluster

HXK3_RAT / P27926 Hexokinase-3; Hexokinase type III; HK III; Hexokinase-C; EC 2.7.1.1 from Rattus norvegicus (Rat)
PFams: Hexokinase_1, Hexokinase_2, Hexokinase_1, Hexokinase_2
924 amino acids: PaperBLAST, CDD, Compare to cluster

P52790 hexokinase-3 (EC 2.7.1.1) from Homo sapiens
HXK3_HUMAN / P52790 Hexokinase-3; Hexokinase type III; HK III; Hexokinase-C; EC 2.7.1.1 from Homo sapiens (Human)
PFams: Hexokinase_1, Hexokinase_2, Hexokinase_1, Hexokinase_2
923 amino acids: PaperBLAST, CDD, Compare to cluster

HKDC1_HUMAN / Q2TB90 Hexokinase HKDC1; Hexokinase domain-containing protein 1; EC 2.7.1.1 from Homo sapiens (Human)
PFams: Hexokinase_1, Hexokinase_2, Hexokinase_1, Hexokinase_2
917 amino acids: PaperBLAST, CDD, Compare to cluster

HKDC1_MOUSE / Q91W97 Hexokinase HKDC1; Hexokinase domain-containing protein 1; EC 2.7.1.1 from Mus musculus (Mouse)
PFams: Hexokinase_1, Hexokinase_2, Hexokinase_1, Hexokinase_2
915 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 4 316-323 amino acids (not heteromeric)

A8LLL9 Glucokinase; EC=2.7.1.2
323 amino acids: PaperBLAST, CDD, Compare to cluster

I7DXX1 Glucokinase Glk; EC=2.7.1.2
316 amino acids: PaperBLAST, CDD, Compare to cluster

b2388 glucokinase (EC 2.7.1.1; EC 2.7.1.2; EC 2.7.1.8) from Escherichia coli K-12 substr. MG1655
P0A6V8 glucokinase (EC 2.7.1.1; EC 2.7.1.8) from Escherichia coli (strain K12)
PFams: Glucokinase
321 amino acids: PaperBLAST, CDD, Compare to cluster

PS417_22685 Glucokinase (EC 2.7.1.2) from Pseudomonas simiae WCS417
PFams: Glucokinase
318 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/8 heteromeric)

A0SZU9 hexokinase (EC 2.7.1.1); glucokinase (EC 2.7.1.2) from Lysinibacillus sphaericus
PFams: ROK
291 amino acids: PaperBLAST, CDD

H6UH58 glucokinase (EC 2.7.1.2) from Staphylococcus aureus
PFams: Glucokinase, ROK
328 amino acids: PaperBLAST, CDD
(similar to BRENDA::B1VZT1 from Cluster 2, but similarity to seed sequence is below thresholds)

Q4E4E1 glucokinase (EC 2.7.1.2) from Trypanosoma cruzi
PFams: Glucokinase
376 amino acids: PaperBLAST, CDD

Q96Y14 hexokinase (EC 2.7.1.1) from Sulfurisphaera tokodaii
PFams: BcrAD_BadFG
299 amino acids: PaperBLAST, CDD

P9WIN1 polyphosphate-dependent glucokinase (EC 2.7.1.63) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
PPGK_MYCTA / A5U654 Polyphosphate glucokinase; Poly(P) glucokinase; ATP-dependent glucokinase; Polyphosphate--glucose phosphotransferase; EC 2.7.1.63; EC 2.7.1.2 from Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra)
PPGK_MYCTU / P9WIN1 Polyphosphate glucokinase; Poly(P) glucokinase; ATP-dependent glucokinase; Polyphosphate--glucose phosphotransferase; EC 2.7.1.63; EC 2.7.1.2 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
PFams: ROK
265 amino acids: PaperBLAST, CDD

HXK1_CANAL / Q59RW5 N-acetylglucosamine kinase 1; GlcNAc kinase 1; Hexokinase 1; EC 2.7.1.59; EC 2.7.1.1 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast)
PFams: Hexokinase_1, Hexokinase_2
493 amino acids: PaperBLAST, CDD

Q5GAN8 General specificity hexokinase
402 amino acids: PaperBLAST, CDD

E2RU42 glucokinase (EC 2.7.1.1) from Giardia intestinalis (strain ATCC 50803 / WB clone C6)
PFams: Glucokinase, ROK
343 amino acids: PaperBLAST, CDD