Clusters of Characterized Proteins

Clustering the characterized proteins for gltP (L-glutamate:cation symporter GltP/GltT) in L-glutamate catabolism

Or see other characterized proteins similar to gltP

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Definition of gltP

• Curated sequence P21345: Proton/glutamate-aspartate symporter; Glutamate-aspartate carrier protein; Proton-glutamate-aspartate transport protein. Glutamate/aspartate:H+ symporter, GltP or GltT; has 8 TMSs with 2 re-entrant loops as for GltPh (TC# 2.A.23.1.5). glutamate/aspartate : H⁺ symporter GltP
• Curated sequence P39817: Proton/glutamate-aspartate symporter; Proton/glutamate symport protein
• Curated sequence CH_088342: proton/sodium-glutamate symport protein GltT. Proton/sodium-glutamate symport protein; Glutamate-aspartate carrier protein
• Curated sequence P24943: Proton/sodium-glutamate symport protein; Glutamate-aspartate carrier protein. proton/sodium-glutamate symport protein GltT. Glutamate/aspartate:Na+ + H+ symporter
• UniProt sequence A1S570: SubName: Full=Sodium:dicarboxylate symporter {ECO:0000313|EMBL:ABL99526.1};
• UniProt sequence L0GT47: SubName: Full=Na+/H+ dicarboxylate symporter {ECO:0000313|EMBL:AGA88545.1};
• Ignore hits to O59010 when looking for 'other' hits (Glutamate transporter homolog; Glt(Ph); Sodium-aspartate symporter Glt(Ph); Sodium-dependent aspartate transporter. Archaeal aspartate transporter, Gltph (GltPh) (3-D structure known; 3V8F and 3V8G) (Boudker et al., 2007; Yernool et al., 2004). Cotransports aspartate with 2 Na+ (Ryan et al., 2009) or 3 Na+ (Groeneveld and Slotboom, 2010) or 1Na+ plus 1 H+ plus 1 K+)

Fetched 6 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 6 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 414-437 amino acids (not heteromeric)

GLTT_BACCA / P24944 Proton/sodium-glutamate symport protein; Glutamate-aspartate carrier protein from Bacillus caldotenax
GI|143002 proton/sodium-glutamate symport protein GltT from Bacillus caldotenax
PFams: SDF
421 amino acids: PaperBLAST, CDD, Compare to cluster

b4077 glutamate/aspartate : H⁺ symporter GltP from Escherichia coli K-12 substr. MG1655
GLTP_ECOLI / P21345 Proton/glutamate-aspartate symporter; Glutamate-aspartate carrier protein; Proton-glutamate-aspartate transport protein from Escherichia coli (strain K12)
TC 2.A.23.1.1 / P21345 Glutamate/aspartate:H+ symporter, GltP or GltT; has 8 TMSs with 2 re-entrant loops as for GltPh (TC# 2.A.23.1.5) from Escherichia coli
PFams: SDF
437 amino acids: PaperBLAST, CDD, Compare to cluster

GLTT_GEOSE / P24943 Proton/sodium-glutamate symport protein; Glutamate-aspartate carrier protein from Geobacillus stearothermophilus (Bacillus stearothermophilus)
TC 2.A.23.1.2 / P24943 Glutamate/aspartate:Na+ + H+ symporter from Bacillus stearothermophilus
GI|143000 proton/sodium-glutamate symport protein GltT from Geobacillus stearothermophilus
PFams: SDF
421 amino acids: PaperBLAST, CDD, Compare to cluster

GLTP_BACSU / P39817 Proton/glutamate-aspartate symporter; Proton/glutamate symport protein from Bacillus subtilis (strain 168)
PFams: SDF
414 amino acids: PaperBLAST, CDD, Compare to cluster

A1S570 Sodium:dicarboxylate symporter
437 amino acids: PaperBLAST, CDD, Compare to cluster

L0GT47 Na+/H+ dicarboxylate symporter
419 amino acids: PaperBLAST, CDD, Compare to cluster