Clusters of Characterized Proteins

GapMind for Amino acid biosynthesis

Clusters of Characterized Proteins

Clustering the characterized proteins for agx1 (alanine--glyoxylate aminotransferase) in glycine biosynthesis

Or see other characterized proteins similar to agx1

Or see all steps for glycine biosynthesis

Or cluster curated proteins matching a keyword

Definition of agx1

Curated proteins or TIGRFams with EC 2.6.1.44
Ignore hits to P84188 when looking for 'other' hits (Serine--glyoxylate aminotransferase; SGAT; Alanine--glyoxylate aminotransferase; AGT; EC 2.6.1.45; EC 2.6.1.44)
Ignore hits to P84187 when looking for 'other' hits (Serine--glyoxylate aminotransferase; SGAT; Alanine--glyoxylate aminotransferase; AGT; EC 2.6.1.45; EC 2.6.1.44)
Comment: P84188 and P84187 are ignored because they appear to be sequence fragments and do not contain the full aminotransferase domain

Fetched 21 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 20 of these sequences

Found 4 clusters of similar sequences. Another 1 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 392-414 amino acids (not heteromeric)

A2V838 alanine-glyoxylate transaminase (EC 2.6.1.44) from Homo sapiens
PFams: Aminotran_5
392 amino acids: PaperBLAST, CDD, Compare to cluster

Q56YA5 serine:glyoxylate aminotransferase (EC 2.6.1.45; EC 2.6.1.4) from Arabidopsis thaliana
SGAT_ARATH / Q56YA5 Serine--glyoxylate aminotransferase; Alanine--glyoxylate aminotransferase; AGT; Asparagine aminotransferase; Serine--pyruvate aminotransferase; EC 2.6.1.45; EC 2.6.1.44; EC 2.6.1.-; EC 2.6.1.51 from Arabidopsis thaliana (Mouse-ear cress)
Q56YA5 asparagine-oxo-acid transaminase (EC 2.6.1.14); alanine-glyoxylate transaminase (EC 2.6.1.44); serine-glyoxylate transaminase (EC 2.6.1.45) from Arabidopsis thaliana
PFams: Aminotran_5
401 amino acids: PaperBLAST, CDD, Compare to cluster

P09139 serine-pyruvate aminotransferase, mitochondrial subunit (EC 2.6.1.51) from Rattus norvegicus
AGT1_RAT / P09139 Alanine--glyoxylate aminotransferase; AGT; Serine--pyruvate aminotransferase, mitochondrial; SPT; EC 2.6.1.44; EC 2.6.1.51 from Rattus norvegicus (Rat)
PFams: Aminotran_5
414 amino acids: PaperBLAST, CDD, Compare to cluster

P21549 Serine--pyruvate aminotransferase (EC 2.6.1.44; EC 2.6.1.51) from Homo sapiens
AGT1_HUMAN / P21549 Alanine--glyoxylate aminotransferase; AGT; Serine--pyruvate aminotransferase; SPT; EC 2.6.1.44; EC 2.6.1.51 from Homo sapiens (Human)
PFams: Aminotran_5
392 amino acids: PaperBLAST, CDD, Compare to cluster

AGT1_RABIT / P31030 Alanine--glyoxylate aminotransferase; AGT; Serine--pyruvate aminotransferase; SPT; EC 2.6.1.44; EC 2.6.1.51 from Oryctolagus cuniculus (Rabbit)
PFams: Aminotran_5
392 amino acids: PaperBLAST, CDD, Compare to cluster

HKT_AEDAE / Q0IG34 3-hydroxykynurenine transaminase; 3-hydroxykynurenine transaminase and alanine--glyoxylate aminotransferase; Ae-HKT/AGT; Alanine--glyoxylate aminotransferase; EC 2.6.1.63; EC 2.6.1.44 from Aedes aegypti (Yellowfever mosquito) (Culex aegypti)
PFams: Aminotran_5
400 amino acids: PaperBLAST, CDD, Compare to cluster

AGT_AEDAE / Q3LSM4 Alanine--glyoxylate aminotransferase; EC 2.6.1.44 from Aedes aegypti (Yellowfever mosquito) (Culex aegypti)
PFams: Aminotran_5
393 amino acids: PaperBLAST, CDD, Compare to cluster

HKT_ANOGA / Q7PRG3 3-hydroxykynurenine transaminase; AgHKT; Alanine--glyoxylate aminotransferase; EC 2.6.1.63; EC 2.6.1.44 from Anopheles gambiae (African malaria mosquito)
PFams: Aminotran_5
396 amino acids: PaperBLAST, CDD, Compare to cluster

AGT_DROME / Q9W3Z3 Alanine--glyoxylate aminotransferase; AGT; EC 2.6.1.44 from Drosophila melanogaster (Fruit fly)
PFams: Aminotran_5
394 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 476-514 amino acids (not heteromeric)

AGT2_MOUSE / Q3UEG6 Alanine--glyoxylate aminotransferase 2, mitochondrial; AGT 2; (R)-3-amino-2-methylpropionate--pyruvate transaminase; Beta-ALAAT II; Beta-alanine-pyruvate aminotransferase; D-AIBAT; EC 2.6.1.44; EC 2.6.1.40 from Mus musculus (Mouse)
Q3UEG6 alanine-glyoxylate transaminase (EC 2.6.1.44) from Mus musculus
PFams: Aminotran_3
513 amino acids: PaperBLAST, CDD, Compare to cluster

Q64565 (R)-3-amino-2-methylpropionate-pyruvate transaminase (EC 2.6.1.40); alanine-glyoxylate transaminase (EC 2.6.1.44) from Rattus norvegicus
PFams: Aminotran_3
512 amino acids: PaperBLAST, CDD, Compare to cluster

Q9BYV1 alanine--glyoxylate aminotransferase 2, mitochondrial (EC 2.6.1.44) from Homo sapiens
AGT2_HUMAN / Q9BYV1 Alanine--glyoxylate aminotransferase 2, mitochondrial; AGT 2; (R)-3-amino-2-methylpropionate--pyruvate transaminase; Beta-ALAAT II; Beta-alanine-pyruvate aminotransferase; D-AIBAT; EC 2.6.1.44; EC 2.6.1.40 from Homo sapiens (Human)
Q9BYV1 alanine-glyoxylate transaminase (EC 2.6.1.44) from Homo sapiens
PFams: Aminotran_3
514 amino acids: PaperBLAST, CDD, Compare to cluster

Q9SR86 beta-alanine-pyruvate transaminase (EC 2.6.1.18); alanine-glyoxylate transaminase (EC 2.6.1.44) from Arabidopsis thaliana
PFams: Aminotran_3
481 amino acids: PaperBLAST, CDD, Compare to cluster

AGT21_ARATH / Q940M2 Alanine--glyoxylate aminotransferase 2 homolog 1, mitochondrial; Beta-alanine-pyruvate aminotransferase 1; EC 2.6.1.44 from Arabidopsis thaliana (Mouse-ear cress)
PFams: Aminotran_3
476 amino acids: PaperBLAST, CDD, Compare to cluster

AGT22_ARATH / Q94AL9 Alanine--glyoxylate aminotransferase 2 homolog 2, mitochondrial; Beta-alanine-pyruvate aminotransferase 2; EC 2.6.1.44 from Arabidopsis thaliana (Mouse-ear cress)
PFams: Aminotran_3
477 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 3 481-521 amino acids (not heteromeric)

Q9LR30 alanine transaminase (EC 2.6.1.44; EC 2.6.1.2; EC 2.6.1.4) from Arabidopsis thaliana
GGT1_ARATH / Q9LR30 Glutamate--glyoxylate aminotransferase 1; AtGGT2; Alanine aminotransferase GGT1; Alanine--glyoxylate aminotransferase GGT1; Alanine-2-oxoglutarate aminotransferase 1; EC 2.6.1.4; EC 2.6.1.2; EC 2.6.1.44; EC 2.6.1.- from Arabidopsis thaliana (Mouse-ear cress)
Q9LR30 gamma-glutamyltransferase (EC 2.3.2.2) from Arabidopsis thaliana
PFams: Aminotran_1_2
481 amino acids: PaperBLAST, CDD, Compare to cluster

Q9S7E9 alanine transaminase (EC 2.6.1.44; EC 2.6.1.2; EC 2.6.1.4) from Arabidopsis thaliana
GGT2_ARATH / Q9S7E9 Glutamate--glyoxylate aminotransferase 2; AtGGT2; Alanine aminotransferase GGT2; Alanine--glyoxylate aminotransferase GGT2; Alanine-2-oxoglutarate aminotransferase 2; EC 2.6.1.4; EC 2.6.1.2; EC 2.6.1.44; EC 2.6.1.- from Arabidopsis thaliana (Mouse-ear cress)
PFams: Aminotran_1_2
481 amino acids: PaperBLAST, CDD, Compare to cluster

Q42685 L-alanine aminotransferase monomer (EC 2.6.1.44; EC 2.6.1.2; EC 2.6.1.4) from Chlamydomonas reinhardtii
PFams: Aminotran_1_2
521 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 4 387-402 amino acids (not heteromeric)

D2Z0I0 alanine-glyoxylate transaminase (EC 2.6.1.44) from Hydrogenobacter thermophilus
PFams: Aminotran_1_2
402 amino acids: PaperBLAST, CDD, Compare to cluster

Q4FNY9 alanine—glyoxylate transaminase (EC 2.6.1.44) from Pelagibacter ubique (strain HTCC1062)
PFams: Aminotran_1_2, DegT_DnrJ_EryC1
387 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/1 heteromeric)

P43567 alanine--glyoxylate aminotransferase subunit (EC 2.6.1.44) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
AGX1_YEAST / P43567 Alanine--glyoxylate aminotransferase 1; EC 2.6.1.44 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
PFams: Aminotran_5
385 amino acids: PaperBLAST, CDD