GapMind for catabolism of small carbon sources

 

Clusters of Characterized Proteins

Clustering the characterized proteins for ivdG (3-hydroxy-2-methylbutyryl-CoA dehydrogenase) in L-isoleucine catabolism

Or see other characterized proteins similar to ivdG

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Or cluster curated proteins matching a keyword

Definition of ivdG

Fetched 5 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 5 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 252-261 amino acids (not heteromeric)

The first sequence in each cluster is the seed.

Q99714 3-hydroxy-2-methylbutyryl-CoA dehydrogenase subunit (EC 1.1.1.35) from Homo sapiens
HCD2_HUMAN / Q99714 3-hydroxyacyl-CoA dehydrogenase type-2; 17-beta-hydroxysteroid dehydrogenase 10; 17-beta-HSD 10; 2-methyl-3-hydroxybutyryl-CoA dehydrogenase; MHBD; 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase type II; Endoplasmic reticulum-associated amyloid beta-peptide-binding protein; Mitochondrial ribonuclease P protein 2; Mitochondrial RNase P protein 2; Short chain dehydrogenase/reductase family 5C member 1; Short-chain type dehydrogenase/reductase XH98G2; Type II HADH; EC 1.1.1.35; EC 1.1.1.51; EC 1.1.1.178 from Homo sapiens (Human)
Q99714 GDP-6-deoxy-D-talose 4-dehydrogenase (EC 1.1.1.135); 3-hydroxy-2-methylbutyryl-CoA dehydrogenase (EC 1.1.1.178) from Bos taurus
PFams: adh_short, KR, adh_short_C2
261 amino acids: PaperBLAST, CDD, Compare to cluster

HCD2_MOUSE / O08756 3-hydroxyacyl-CoA dehydrogenase type-2; 17-beta-hydroxysteroid dehydrogenase 10; 17-beta-HSD 10; 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase type II; Endoplasmic reticulum-associated amyloid beta-peptide-binding protein; Mitochondrial ribonuclease P protein 2; Mitochondrial RNase P protein 2; Type II HADH; EC 1.1.1.35; EC 1.1.1.51; EC 1.1.1.178 from Mus musculus (Mouse)
PFams: adh_short, KR, adh_short_C2
261 amino acids: PaperBLAST, CDD, Compare to cluster

HCD2_DROME / O18404 3-hydroxyacyl-CoA dehydrogenase type-2; 17-beta-hydroxysteroid dehydrogenase 10; 17-beta-HSD 10; 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; 3-hydroxyacyl-CoA dehydrogenase type II; Mitochondrial ribonuclease P protein 2; Mitochondrial RNase P protein 2; Scully protein; Type II HADH; EC 1.1.1.35; EC 1.1.1.51; EC 1.1.1.178 from Drosophila melanogaster (Fruit fly)
PFams: KR, adh_short, Epimerase, adh_short_C2
255 amino acids: PaperBLAST, CDD, Compare to cluster

Q8EGC1 3-hydroxyacyl-CoA dehydrogenase IvdG; EC=1.1.1.35
252 amino acids: PaperBLAST, CDD, Compare to cluster

Q88KS5 3-hydroxy-2-methylbutyryl-CoA dehydrogenase subunit (EC 1.1.1.178) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
PFams: adh_short, KR, adh_short_C2
255 amino acids: PaperBLAST, CDD, Compare to cluster