Clusters of Characterized Proteins

Clustering the characterized proteins for livJ (L-isoleucine ABC transporter, substrate-binding component (LivJ/LivK/BraC/BraC3)) in L-isoleucine catabolism

Or see other characterized proteins similar to livJ

Or see all steps for L-isoleucine catabolism

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Definition of livJ

• Curated sequence P21175: Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein; LIVAT-BP; Leu/Ile/Val/Thr/Ala-binding protein. Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein, component of Branched chain amino acid uptake transporter. Transports alanine
• Curated sequence CH_107418: leucine-specific-binding protein LivK. Livk aka B3458, component of Leucine; leucine/isoleucine/valine porter. L-leucine/L-phenylalanine ABC transporter periplasmic binding protein (EC 7.4.2.2). L-leucine/L-phenylalanine ABC transporter periplasmic binding protein (EC 7.4.2.2)
• Curated sequence P0AD96: Leu/Ile/Val-binding protein LivJ aka B3460 aka LIV-BP, component of Leucine; leucine/isoleucine/valine porter. branched chain amino acid/phenylalanine ABC transporter periplasmic binding protein (EC 7.4.2.2). branched chain amino acid/phenylalanine ABC transporter periplasmic binding protein (EC 7.4.2.2)
• Curated sequence Q8DQI1: ABC transporter substrate-binding protein-branched chain amino acid transport, component of The branched chain hydrophobic amino acid transporter, LivJFGHM
• UniProt sequence Q1MDE9: SubName: Full=Solute-binding (Aliphatic amino acid) component of ABC transporter {ECO:0000313|EMBL:CAK09028.1};
• Ignore hits to Q9L3M3 when looking for 'other' hits (BraC, component of General L- (and D-)amino acid uptake porter (transports acidic, basic, polar, semipolar and hydrophobic amino acids). The amino and carboxyl groups do not need to be α since γ-aminobutyric acid (GABA) is a substrate. The system may function with additional binding proteins since L-alanine uptake is not dependent on BraC)
• UniProt sequence A0A165KTD4: SubName: Full=Branched chain amino acid ABC transporter substrate-binding protein {ECO:0000313|EMBL:KZT16064.1};
• UniProt sequence A0A160A0J6: SubName: Full=Leucine ABC transporter subunit substrate-binding protein LivK {ECO:0000313|EMBL:AMZ72282.1};

Fetched 7 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 7 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 367-386 amino acids (4/7 heteromeric)

BRAC_PSEAE / P21175 Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein; LIVAT-BP; Leu/Ile/Val/Thr/Ala-binding protein from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
TC 3.A.1.4.8 / P21175 Leucine-, isoleucine-, valine-, threonine-, and alanine-binding protein, component of Branched chain amino acid uptake transporter. Transports alanine from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
PFams: Peripla_BP_6, Peripla_BP_5, ANF_receptor
Heteromeric, 373 amino acids: PaperBLAST, CDD, Compare to cluster

b3458 L-leucine/L-phenylalanine ABC transporter periplasmic binding protein (EC 7.4.2.2) from Escherichia coli K-12 substr. MG1655
P04816 L-leucine/L-phenylalanine ABC transporter periplasmic binding protein (EC 7.4.2.2) from Escherichia coli (strain K12)
TC 3.A.1.4.1 / P04816 Livk aka B3458, component of Leucine; leucine/isoleucine/valine porter from Escherichia coli
CH_107418 leucine-specific-binding protein LivK from Escherichia coli K12
PFams: Peripla_BP_5, Peripla_BP_6, ANF_receptor
Heteromeric, 369 amino acids: PaperBLAST, CDD, Compare to cluster

b3460 branched chain amino acid/phenylalanine ABC transporter periplasmic binding protein (EC 7.4.2.2) from Escherichia coli K-12 substr. MG1655
P0AD96 branched chain amino acid/phenylalanine ABC transporter periplasmic binding protein (EC 7.4.2.2) from Escherichia coli (strain K12)
TC 3.A.1.4.1 / P0AD96 Leu/Ile/Val-binding protein LivJ aka B3460 aka LIV-BP, component of Leucine; leucine/isoleucine/valine porter from Escherichia coli
PFams: Peripla_BP_5, Peripla_BP_6, ANF_receptor
Heteromeric, 367 amino acids: PaperBLAST, CDD, Compare to cluster

TC 3.A.1.4.10 / Q8DQI1 ABC transporter substrate-binding protein-branched chain amino acid transport, component of The branched chain hydrophobic amino acid transporter, LivJFGHM from Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
PFams: Peripla_BP_6, Peripla_BP_5, ANF_receptor
Heteromeric, 386 amino acids: PaperBLAST, CDD, Compare to cluster

A0A160A0J6 Leucine ABC transporter subunit substrate-binding protein LivK
375 amino acids: PaperBLAST, CDD, Compare to cluster

A0A165KTD4 Branched chain amino acid ABC transporter substrate-binding protein
375 amino acids: PaperBLAST, CDD, Compare to cluster

Q1MDE9 Solute-binding (Aliphatic amino acid) component of ABC transporter
367 amino acids: PaperBLAST, CDD, Compare to cluster