Clusters of Characterized Proteins

GapMind for catabolism of small carbon sources

Clusters of Characterized Proteins

Clustering the characterized proteins for galdh (D-galactose 1-dehydrogenase (forming 1,4- or 1,5-lactones)) in lactose catabolism

Or see other characterized proteins similar to galdh

Or see all steps for lactose catabolism

Or cluster curated proteins matching a keyword

Definition of galdh

Curated proteins or TIGRFams with EC 1.1.1.48
Curated proteins or TIGRFams with EC 1.1.1.360
Ignore hits to items matching 1.1.1.46 when looking for 'other' hits
Curated sequence Q92RN6: Probable galactose dehydrogenase GalD; EC 1.1.1.-
Comment: Some L-arabinose dehydrogenases (EC 1.1.1.46) are bifunctional. Q92RN6 is annotated as a probable galactose dehydrogenase, and mutants are defective in utilization, but was not given this EC number.

Fetched 13 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 13 of these sequences

Found 3 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 256-280 amino acids (not heteromeric)

GALD_RHIME / Q92RN6 Probable galactose dehydrogenase GalD; EC 1.1.1.- from Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti)
PFams: Epimerase, KR, adh_short, adh_short_C2
256 amino acids: PaperBLAST, CDD, Compare to cluster

BPHYT_RS16920 L-arabinose 1-dehydrogenase; D-galactose 1-dehydrogenase (EC 1.1.1.46; EC 1.1.1.48) from Burkholderia phytofirmans PsJN
PFams: KR, adh_short, Epimerase, adh_short_C2
266 amino acids: PaperBLAST, CDD, Compare to cluster

Ac3H11_614 L-arabinose 1-dehydrogenase; D-galactose 1-dehydrogenase (EC 1.1.1.46; EC 1.1.1.48) from Acidovorax sp. GW101-3H11
PFams: adh_short, adh_short_C2
280 amino acids: PaperBLAST, CDD, Compare to cluster

PfGW456L13_2119 L-arabinose 1-dehydrogenase / D-galactose 1-dehydrogenase (EC 1.1.1.46; EC 1.1.1.48) from Pseudomonas fluorescens GW456-L13
PFams: adh_short, KR, adh_short_C2
272 amino acids: PaperBLAST, CDD, Compare to cluster

Pf1N1B4_412 L-arabinose 1-dehydrogenase / D-galactose 1-dehydrogenase (EC 1.1.1.46; EC 1.1.1.48) from Pseudomonas fluorescens FW300-N1B4
PFams: adh_short, KR, adh_short_C2
272 amino acids: PaperBLAST, CDD, Compare to cluster

Pf6N2E2_5967 L-arabinose 1-dehydrogenase / D-galactose 1-dehydrogenase (EC 1.1.1.46; EC 1.1.1.48) from Pseudomonas fluorescens FW300-N2E2
PFams: adh_short, KR, adh_short_C2
272 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 359-366 amino acids (not heteromeric)

O93715 aldose 1-dehydrogenase subunit (EC 1.1.1.376; EC 1.1.1.359; EC 1.1.1.119) from Saccharolobus solfataricus
GLCDH_SACSO / O93715 Glucose 1-dehydrogenase; GDH; GlcDH; Aldose 1-dehydrogenase [NAD(P)(+)]; Galactose 1-dehydrogenase; EC 1.1.1.47; EC 1.1.1.359; EC 1.1.1.120; EC 1.1.1.48 from Saccharolobus solfataricus (Sulfolobus solfataricus)
O93715 aldose 1-dehydrogenase [NAD(P)+] (EC 1.1.1.359) from Saccharolobus solfataricus
Q7LYI9 aldose 1-dehydrogenase [NAD(P)+] (EC 1.1.1.359) from Saccharolobus solfataricus
PFams: ADH_N, Glu_dehyd_C
366 amino acids: PaperBLAST, CDD, Compare to cluster

P13203 glucose dehydrogenase subunit (EC 1.1.1.119) from Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
GLCDH_THEAC / P13203 Glucose 1-dehydrogenase; GDH; GlcDH; Galactose 1-dehydrogenase; EC 1.1.1.47; EC 1.1.1.120; EC 1.1.1.48 from Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165)
P13203 aldose 1-dehydrogenase [NAD(P)+] (EC 1.1.1.359) from Thermoplasma acidophilum
PFams: ADH_N, Glu_dehyd_C
361 amino acids: PaperBLAST, CDD, Compare to cluster

Q979W2 glucose/galactose 1-dehydrogenase (EC 1.1.1.360) from Thermoplasma volcanium
PFams: ADH_N, Glu_dehyd_C
361 amino acids: PaperBLAST, CDD, Compare to cluster

GLCD2_PICTO / Q6L047 Glucose/galactose 1-dehydrogenase; Galactose 1-dehydrogenase [NADP(+)]; Glucose 1-dehydrogenase 2; GDH 2; GlcDH 2; EC 1.1.1.360 from Picrophilus torridus (strain ATCC 700027 / DSM 9790 / JCM 10055 / NBRC 100828)
PFams: ADH_N, Glu_dehyd_C
359 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 3 304-309 amino acids (not heteromeric)

P11886 D-galactose dehydrogenase subunit (EC 1.1.1.48) from Pseudomonas fluorescens
GAL_PSEFL / P11886 Galactose 1-dehydrogenase; EC 1.1.1.48 from Pseudomonas fluorescens
PFams: GFO_IDH_MocA
304 amino acids: PaperBLAST, CDD, Compare to cluster

ARAA_AZOBR / Q53TZ2 L-arabinose 1-dehydrogenase (NAD(P)(+)); D-galactose 1-dehydrogenase; EC 1.1.1.376; EC 1.1.1.120; EC 1.1.1.48 from Azospirillum brasilense
Q53TZ2 L-arabinose 1-dehydrogenase [NAD(P)+] (EC 1.1.1.376) from Azospirillum brasilense
PFams: GFO_IDH_MocA
309 amino acids: PaperBLAST, CDD, Compare to cluster

SMc00588 L-arabinose 1-dehydrogenase; D-galactose 1-dehydrogenase (EC 1.1.1.46; EC 1.1.1.48) from Sinorhizobium meliloti 1021
PFams: GFO_IDH_MocA
308 amino acids: PaperBLAST, CDD, Compare to cluster