Clusters of Characterized Proteins

Clustering the characterized proteins for gtsD (glucose ABC transporter, ATPase component (GtsD)) in lactose catabolism

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Definition of gtsD

• Curated sequence Q72L52: Sugar-binding transport ATP-binding protein aka MalK1 aka TT_C0211, component of The trehalose/maltose/sucrose/palatinose porter (TTC1627-9) plus MalK1 (ABC protein, shared with 3.A.1.1.24) (Silva et al. 2005; Chevance et al., 2006). The receptor (TTC1627) binds disaccharide alpha-glycosides, namely trehalose (alpha-1,1), sucrose (alpha-1,2), maltose (alpha-1,4), palatinose (alpha-1,6) and glucose
• Ignore hits to Q97UY8 when looking for 'other' hits (monosaccharide-transporting ATPase (EC 3.6.3.17). Glucose import ATP-binding protein GlcV; EC 7.5.2.-. GlcV, component of Glucose, mannose, galactose porter)
• Curated sequence Q88P35: GtsD (GLcK), component of Glucose porter, GtsABCD
• Curated sequence PfGW456L13_1897: ABC transporter for D-Galactose and D-Glucose, ATPase component
• Curated sequence GFF4321: ABC transporter for D-Glucose-6-Phosphate, ATPase component
• UniProt sequence A0A165KQ08: SubName: Full=Sugar ABC transporter ATP-binding protein {ECO:0000313|EMBL:KZT15785.1};

Fetched 5 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 5 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 355-386 amino acids (4/5 heteromeric)

TC 3.A.1.1.24 / TC 3.A.1.1.25 / Q72L52 Sugar-binding transport ATP-binding protein aka MalK1 aka TT_C0211, component of The trehalose/maltose/sucrose/palatinose porter (TTC1627-9) plus MalK1 (ABC protein, shared with 3.A.1.1.24) (Silva et al. 2005; Chevance et al., 2006). The receptor (TTC1627) binds disaccharide alpha-glycosides, namely trehalose (alpha-1,1), sucrose (alpha-1,2), maltose (alpha-1,4), palatinose (alpha-1,6) and glucose from Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039)
PFams: ABC_tran, OB_MalK, TOBE_2, TOBE
Heteromeric, 376 amino acids: PaperBLAST, CDD, Compare to cluster

TC 3.A.1.1.30 / Q88P35 GtsD (GLcK), component of Glucose porter, GtsABCD from Pseudomonas putida (strain KT2440)
PFams: ABC_tran, OB_MalK, TOBE_2, TOBE
Heteromeric, 384 amino acids: PaperBLAST, CDD, Compare to cluster

A0A165KQ08 Sugar ABC transporter ATP-binding protein
355 amino acids: PaperBLAST, CDD, Compare to cluster

PS417_22130 ABC transporter for D-Glucose-6-Phosphate, ATPase component from Pseudomonas simiae WCS417
PFams: ABC_tran, OB_MalK, TOBE_2, TOBE
Heteromeric, 386 amino acids: PaperBLAST, CDD, Compare to cluster

PfGW456L13_1897 ABC transporter for D-Galactose and D-Glucose, ATPase component from Pseudomonas fluorescens GW456-L13
PFams: ABC_tran, OB_MalK, TOBE_2, TOBE
Heteromeric, 386 amino acids: PaperBLAST, CDD, Compare to cluster