Clusters of Characterized Proteins
Clustering the characterized proteins for ptsG (glucose PTS, enzyme IICB) in lactose catabolism
Or see other characterized proteins similar to ptsG
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Definition of ptsG
- Ignore hits to Q9AGA7 when looking for 'other' hits (PTS system alpha-glucoside-specific EIICB component; EC 2.7.1.-. The α-glucoside-specific IICB, AglB (transports glucose, methyl-α-glucoside, maltitol, isomaltose, trehalulose α(1→1), turanose α(1→3), maltulose α(1→4), leucrose α(1→5), and palatinose α(1→6), but not sucrose (most resembles 4.A.1.1.4 and 4.A.1.1.8))
- Curated sequence P69786: protein-Npi-phosphohistidine-D-glucose phosphotransferase (EC 2.7.1.199). PTS system glucose-specific EIICB component; EC 2.7.1.69. PTS system glucose-specific EIICB component; EIICB-Glc; EII-Glc; EC 2.7.1.199. PTS system glucose-specific EIICB component PTGB aka PTSG aka GLCA aka UMG aka B1101, component of Glucose porter (PtsG; GlcA; Umg) (transports D-glucose and α-methyl-D-glucopyranoside). glucose-specific PTS enzyme IIBC component (EC 2.7.1.199). glucose-specific PTS enzyme IIBC component (EC 2.7.1.199)
- Curated sequence P37439: PTS system glucose-specific EIICB component; EIICB-Glc; EII-Glc; EC 2.7.1.199
- Ignore hits to O51590 when looking for 'other' hits (Glucose-specific Enzyme IIBC of the PTS, PtsG)
- Ignore hits to P19642 when looking for 'other' hits (PTS system maltose- and glucose-specific EIICB component; EC 2.7.1.69. PTS system maltose-specific EIICB component; EC 2.7.1.208. Maltose porter (MalX). PTS enzyme IIBC component MalX. PTS enzyme IIBC component MalX)
- Comment: EII-CB proteins. Ignore O51590 (4.A.1.1.18) from Borrelia burgdorferi, which is not characterized and the EIIA component is uncertain. Ignore E. coli malX (P19642), which facilitates diffusion of glucose (no phosphorylation); its physiological function is unclear so it is not listed as a sole glucose transporter. Ignore PTUCB_KLEPN / Q9AGA7 from Klebsiella, as the EII-A component was not described
Fetched 2 sequences
Running BLASTp
Found similarities, at above 30% identity and 75% coverage, for 2 of these sequences
Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism
Cluster 1 477-477 amino acids (1/2 heteromeric)
The first sequence in each cluster is the seed.b1101 glucose-specific PTS enzyme IIBC component (EC 2.7.1.199) from Escherichia coli K-12 substr. MG1655
P69786 glucose-specific PTS enzyme IIBC component (EC 2.7.1.199) from Escherichia coli (strain K12)
PTGCB_ECOLI / P69786 PTS system glucose-specific EIICB component; EIICB-Glc; EII-Glc; EC 2.7.1.199 from Escherichia coli (strain K12)
P69786 protein-Npi-phosphohistidine-D-glucose phosphotransferase (EC 2.7.1.199) from Escherichia coli
TC 4.A.1.1.1 / P69786 PTS system glucose-specific EIICB component PTGB aka PTSG aka GLCA aka UMG aka B1101, component of Glucose porter (PtsG; GlcA; Umg) (transports D-glucose and α-methyl-D-glucopyranoside) from Escherichia coli
MB|P69786 PTS system glucose-specific EIICB component; EC 2.7.1.69 from Escherichia coli K12
PFams: PTS_EIIC, PTS_EIIB
Heteromeric, 477 amino acids: PaperBLAST, CDD, Compare to cluster
PTGCB_SALTY / P37439 PTS system glucose-specific EIICB component; EIICB-Glc; EII-Glc; EC 2.7.1.199 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720)
PFams: PTS_EIIC, PTS_EIIB
477 amino acids: PaperBLAST, CDD, Compare to cluster