GapMind for catabolism of small carbon sources

 

Clusters of Characterized Proteins

Clustering the characterized proteins for liuC (3-methylglutaconyl-CoA hydratase) in L-leucine catabolism

Or see other characterized proteins similar to liuC

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Or cluster curated proteins matching a keyword

Definition of liuC

Fetched 10 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 9 of these sequences

Found 1 clusters of similar sequences. Another 3 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 258-339 amino acids (not heteromeric)

The first sequence in each cluster is the seed.

Q92VJ6 Putative enoyl-CoA hydratase protein; EC=4.2.1.17
261 amino acids: PaperBLAST, CDD, Compare to cluster

Q13825 methylglutaconyl-CoA hydratase subunit (EC 4.2.1.18) from Homo sapiens
AUHM_HUMAN / Q13825 Methylglutaconyl-CoA hydratase, mitochondrial; AU-specific RNA-binding enoyl-CoA hydratase; AU-binding protein/enoyl-CoA hydratase; Itaconyl-CoA hydratase; EC 4.2.1.18; EC 4.2.1.56 from Homo sapiens (Human)
Q13825 methylglutaconyl-CoA hydratase (EC 4.2.1.18) from Homo sapiens
PFams: ECH_1, ECH_2
339 amino acids: PaperBLAST, CDD, Compare to cluster

Q1D5Y4 methylglutaconyl-CoA hydratase (EC 4.2.1.18) from Myxococcus xanthus
PFams: ECH_2, ECH_1
258 amino acids: PaperBLAST, CDD, Compare to cluster

AUHM_MOUSE / Q9JLZ3 Methylglutaconyl-CoA hydratase, mitochondrial; AU-specific RNA-binding enoyl-CoA hydratase; AU-binding enoyl-CoA hydratase; muAUH; Itaconyl-CoA hydratase; EC 4.2.1.18; EC 4.2.1.56 from Mus musculus (Mouse)
PFams: ECH_1, ECH_2
314 amino acids: PaperBLAST, CDD, Compare to cluster

Q88FM3 3-methylglutaconyl-CoA hydratase (EC 4.2.1.18) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / NCIMB 11950 / KT2440)
PFams: ECH_1, ECH_2
271 amino acids: PaperBLAST, CDD, Compare to cluster

AO356_01590 Methylglutaconyl-CoA hydratase (EC 4.2.1.18) from Pseudomonas fluorescens FW300-N2C3
PFams: ECH_1, ECH_2
273 amino acids: PaperBLAST, CDD, Compare to cluster

Pf6N2E2_2193 Methylglutaconyl-CoA hydratase (EC 4.2.1.18) from Pseudomonas fluorescens FW300-N2E2
PFams: ECH_1, ECH_2
272 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/3 heteromeric)

F4JML5 methylglutaconyl-CoA hydratase (EC 4.2.1.18) from Arabidopsis thaliana
PFams: ECH_1, ECH_2
301 amino acids: PaperBLAST, CDD
(similar to BRENDA::Q13825 from Cluster 1, but similarity to seed sequence is below thresholds)

CH_122457 3-hydroxy-3-methylglutaryl-coenzyme A lyase/3-methylglutaconyl-coenzyme A hydratase; EC 4.1.3.4; EC 4.2.1.18 from Emericella nidulans
PFams: HMGL-like, ECH_1, ECH_2
599 amino acids: PaperBLAST, CDD

CA265_RS09125 Methylglutaconyl-CoA hydratase (EC 4.2.1.18) from Pedobacter sp. GW460-11-11-14-LB5
PFams: ECH_1, ECH_2
258 amino acids: PaperBLAST, CDD
(similar to metacyc::MONOMER-16071 from Cluster 1, but similarity to seed sequence is below thresholds)