GapMind for Amino acid biosynthesis

 

Clusters of Characterized Proteins

Clustering the characterized proteins for hcs (homocitrate synthase) in L-lysine biosynthesis

Or see other characterized proteins similar to hcs

Or see all steps for L-lysine biosynthesis

Or cluster curated proteins matching a keyword

Definition of hcs

Fetched 14 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 14 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 376-540 amino acids (not heteromeric)

The first sequence in each cluster is the seed.

HOSA_SULTO / Q971S5 Homocitrate synthase; HCS; EC 2.3.3.14 from Sulfurisphaera tokodaii (strain DSM 16993 / JCM 10545 / NBRC 100140 / 7) (Sulfolobus tokodaii)
PFams: HMGL-like, AsnC_trans_reg
460 amino acids: PaperBLAST, CDD, Compare to cluster

A0A0S6UXF5 homocitrate synthase (EC 2.3.3.14) from Bradyrhizobium sp. DOA9
PFams: HMGL-like
400 amino acids: PaperBLAST, CDD, Compare to cluster

A0A1Y6KBA1 homocitrate synthase (EC 2.3.3.14) from Bradyrhizobium sp. ORS 285
PFams: HMGL-like
416 amino acids: PaperBLAST, CDD, Compare to cluster

C7C437 homocitrate synthase (EC 2.3.3.14) from Aspergillus fumigatus
PFams: HMGL-like
463 amino acids: PaperBLAST, CDD, Compare to cluster

D0VY45 homocitrate synthase (EC 2.3.3.14) from Lotus japonicus
PFams: HMGL-like, LeuA_dimer
540 amino acids: PaperBLAST, CDD, Compare to cluster

M1U949 homocitrate synthase (EC 2.3.3.14) from Flammulina velutipes
PFams: HMGL-like
464 amino acids: PaperBLAST, CDD, Compare to cluster

P48570 homocitrate synthase (EC 2.3.3.14) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
HOSC_YEAST / P48570 Homocitrate synthase, cytosolic isozyme; HCS; EC 2.3.3.14 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
P48570 homocitrate synthase (EC 2.3.3.14) from Saccharomyces cerevisiae
PFams: HMGL-like
428 amino acids: PaperBLAST, CDD, Compare to cluster

P58637 homocitrate synthase (EC 2.3.3.14) from Nostoc sp. PCC 7120 = FACHB-418
PFams: HMGL-like
376 amino acids: PaperBLAST, CDD, Compare to cluster

Q12122 homocitrate synthase (EC 2.3.3.14) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c)
HOSM_YEAST / Q12122 Homocitrate synthase, mitochondrial; HCS; EC 2.3.3.14 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Q12122 homocitrate synthase (EC 2.3.3.14) from Saccharomyces cerevisiae
PFams: HMGL-like
440 amino acids: PaperBLAST, CDD, Compare to cluster

HOSA_SULAC / Q4J989 Homocitrate synthase; HCS; EC 2.3.3.14 from Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770)
Q4J989 homocitrate synthase (EC 2.3.3.14) from Sulfolobus acidocaldarius
PFams: HMGL-like, AsnC_trans_reg
468 amino acids: PaperBLAST, CDD, Compare to cluster

HOSM_SCHPO / Q9Y823 Homocitrate synthase, mitochondrial; HCS; EC 2.3.3.14 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
RF|NP_596458.1 homocitrate synthase (predicted); EC 2.3.3.14 from Schizosaccharomyces pombe
PFams: HMGL-like
418 amino acids: PaperBLAST, CDD, Compare to cluster

O87198 homocitrate synthase (EC 2.3.3.14) from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27)
HOSA_THET2 / O87198 Homocitrate synthase; HCS; EC 2.3.3.14 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27)
PFams: HMGL-like
376 amino acids: PaperBLAST, CDD, Compare to cluster

P05342 homocitrate synthase monomer (EC 2.3.3.14) from Azotobacter vinelandii
NIFV_AZOVI / P05342 Homocitrate synthase; EC 2.3.3.14 from Azotobacter vinelandii
PFams: HMGL-like
385 amino acids: PaperBLAST, CDD, Compare to cluster

AKSA_METJA / Q57926 Homocitrate synthase AksA; (R)-homo(2)citrate synthase; (R)-homo(3)citrate synthase; EC 2.3.3.14; EC 2.3.3.- from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii)
PFams: HMGL-like
406 amino acids: PaperBLAST, CDD, Compare to cluster