Clusters of Characterized Proteins

GapMind for catabolism of small carbon sources

Clusters of Characterized Proteins

Clustering the characterized proteins for bcd (butanoyl-CoA dehydrogenase (NAD+, ferredoxin), dehydrogenase subunit) in L-lysine catabolism

Or see other characterized proteins similar to bcd

Or see all steps for L-lysine catabolism

Or cluster curated proteins matching a keyword

Definition of bcd

Curated sequence D2RL84: butanoyl-CoA dehydrogenase (NAD+, ferredoxin) (subunit 1/3) (EC 1.3.1.109); short-chain acyl-CoA dehydrogenase (subunit 1/2) (EC 1.3.8.1)
Curated sequence Q18AQ1: butanoyl-CoA dehydrogenase (NAD+, ferredoxin) (subunit 3/3) (EC 1.3.1.109); short-chain acyl-CoA dehydrogenase (EC 1.3.8.1)
Ignore hits to D9TQ00 when looking for 'other' hits (butanal dehydrogenase (EC 1.2.1.57))
Curated sequence P52042: butyryl-CoA dehydrogenase; EC 1.3.99.2. Acyl-CoA dehydrogenase, short-chain specific; Butyryl-CoA dehydrogenase; SCAD; EC 1.3.8.1. butyryl-CoA dehydrogenase (EC 1.3.8.1)
Curated sequence MONOMER-11937: butyryl-CoA dehydrogenase; EC 1.3.99.2. butyryl-CoA dehydrogenase subunit (EC 1.3.8.1)
Curated sequence MONOMER-13470: butyryl-CoA dehydrogenase (EC 1.3.8.1)
Comment: D9TQ00 is probably misannotated in BRENDA P52042 and metacyc::MONOMER-13470 and metacyc::MONOMER-11937 were given EC 1.3.8.1 (which means electron transfer to etf, but no electron bifurcation expected), but are probably electron bifurcating

Fetched 5 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 5 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 378-383 amino acids (2/5 heteromeric)

The first sequence in each cluster is the seed.

D2RL84 butanoyl-CoA dehydrogenase (NAD+, ferredoxin) (subunit 1/3) (EC 1.3.1.109); short-chain acyl-CoA dehydrogenase (subunit 1/2) (EC 1.3.8.1) from Acidaminococcus fermentans
PFams: Acyl-CoA_dh_N, Acyl-CoA_dh_M, Acyl-CoA_dh_1, Acyl-CoA_dh_2
Heteromeric, 383 amino acids: PaperBLAST, CDD, Compare to cluster

Q18AQ1 butanoyl-CoA dehydrogenase (NAD+, ferredoxin) (subunit 3/3) (EC 1.3.1.109); short-chain acyl-CoA dehydrogenase (EC 1.3.8.1) from Clostridioides difficile
PFams: Acyl-CoA_dh_N, Acyl-CoA_dh_M, Acyl-CoA_dh_1, Acyl-CoA_dh_2
Heteromeric, 378 amino acids: PaperBLAST, CDD, Compare to cluster

P52042 butyryl-CoA dehydrogenase (EC 1.3.8.1) from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
ACDS_CLOAB / P52042 Acyl-CoA dehydrogenase, short-chain specific; Butyryl-CoA dehydrogenase; SCAD; EC 1.3.8.1 from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
CH_091785 butyryl-CoA dehydrogenase; EC 1.3.99.2 from Clostridium acetobutylicum
PFams: Acyl-CoA_dh_N, Acyl-CoA_dh_M, Acyl-CoA_dh_1, Acyl-CoA_dh_2
379 amino acids: PaperBLAST, CDD, Compare to cluster

Q06319 butyryl-CoA dehydrogenase subunit (EC 1.3.8.1) from Megasphaera elsdenii
GI|149886 butyryl-CoA dehydrogenase; EC 1.3.99.2 from Megasphaera elsdenii
PFams: Acyl-CoA_dh_N, Acyl-CoA_dh_M, Acyl-CoA_dh_1, Acyl-CoA_dh_2
383 amino acids: PaperBLAST, CDD, Compare to cluster

A5N5C8 butyryl-CoA dehydrogenase (EC 1.3.8.1) from Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680)
PFams: Acyl-CoA_dh_N, Acyl-CoA_dh_M, Acyl-CoA_dh_1, Acyl-CoA_dh_2
379 amino acids: PaperBLAST, CDD, Compare to cluster