Clusters of Characterized Proteins

Clustering the characterized proteins for cadA (lysine decarboxylase) in L-lysine catabolism

Or see other characterized proteins similar to cadA

Or see all steps for L-lysine catabolism

Or cluster curated proteins matching a keyword

Definition of cadA

• Curated proteins or TIGRFams with EC 4.1.1.18
• Ignore hits to A0A0H3H393 when looking for 'other' hits (lysine decarboxylase (EC 4.1.1.18))
• Comment: A0A0H3H393 is very similar to E. coli diaminopimelate decarboxylase and could not access the paper about it, so do not trust it.

Fetched 11 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 9 of these sequences

Found 2 clusters of similar sequences. Another 2 sequences are not clustered. Download as table or as draft rules or view by organism

Cluster 1 709-751 amino acids (not heteromeric)

A0A094XEM2 lysine decarboxylase (EC 4.1.1.18) from Klebsiella aerogenes
PFams: OKR_DC_1_N, OKR_DC_1, OKR_DC_1_C
715 amino acids: PaperBLAST, CDD, Compare to cluster

A0A0H3FP92 lysine decarboxylase (EC 4.1.1.18) from Klebsiella aerogenes
PFams: OKR_DC_1_N, OKR_DC_1, OKR_DC_1_C
712 amino acids: PaperBLAST, CDD, Compare to cluster

b4131 lysine decarboxylase 1 (EC 4.1.1.18) from Escherichia coli K-12 substr. MG1655
P0A9H3 lysine decarboxylase 1 (EC 4.1.1.18) from Escherichia coli (strain K12)
LDCI_ECOLI / P0A9H3 Inducible lysine decarboxylase; LDCI; EC 4.1.1.18 from Escherichia coli (strain K12)
P0A9H3 lysine decarboxylase (EC 4.1.1.18) from Escherichia coli
RF|NP_418555 lysine decarboxylase, inducible; EC 4.1.1.18 from Escherichia coli K12
PFams: OKR_DC_1_N, OKR_DC_1, OKR_DC_1_C
715 amino acids: PaperBLAST, CDD, Compare to cluster

b0186 lysine decarboxylase 2 (EC 4.1.1.18) from Escherichia coli K-12 substr. MG1655
P52095 lysine decarboxylase 2 (EC 4.1.1.18) from Escherichia coli (strain K12)
LDCC_ECOLI / P52095 Constitutive lysine decarboxylase; LDCC; EC 4.1.1.18 from Escherichia coli (strain K12)
P52095 lysine decarboxylase (EC 4.1.1.18) from Escherichia coli
GB|BAA21656.1 lysine decarboxylase, constitutive; EC 4.1.1.18 from Escherichia coli K12
PFams: OKR_DC_1_N, OKR_DC_1, OKR_DC_1_C
713 amino acids: PaperBLAST, CDD, Compare to cluster

Q87KT6 lysine decarboxylase (EC 4.1.1.18) from Vibrio parahaemolyticus
PFams: OKR_DC_1_N, OKR_DC_1, OKR_DC_1_C
711 amino acids: PaperBLAST, CDD, Compare to cluster

Q9Z4R7 lysine decarboxylase (EC 4.1.1.18) from Eikenella corrodens
PFams: OKR_DC_1_N, OKR_DC_1, OKR_DC_1_C
709 amino acids: PaperBLAST, CDD, Compare to cluster

LDCA_PSEAE / Q9I2S7 Lysine decarboxylase LdcA; EC 4.1.1.18 from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)
PFams: OKR_DC_1_N, OKR_DC_1, OKR_DC_1_C
751 amino acids: PaperBLAST, CDD, Compare to cluster

Cluster 2 480-515 amino acids (not heteromeric)

Q9L072 L-lysine decarboxylase (EC 4.1.1.18) from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
Q9L072 lysine decarboxylase (EC 4.1.1.18) from Streptomyces coelicolor
PFams: Pyridoxal_deC, Beta_elim_lyase, Aminotran_5, SepSecS
480 amino acids: PaperBLAST, CDD, Compare to cluster

B6EP92 L-lysine decarboxylase (EC 4.1.1.18) from Aliivibrio salmonicida (strain LFI1238)
PFams: Pyridoxal_deC
515 amino acids: PaperBLAST, CDD, Compare to cluster

Singletons (0/2 heteromeric)

A0A2Z4EVE5 lysine decarboxylase (EC 4.1.1.18) from Morus alba
PFams: LDcluster4, Lysine_decarbox
218 amino acids: PaperBLAST, CDD

O50657 L-lysine decarboxylase monomer (EC 4.1.1.18) from Selenomonas ruminantium
O50657 lysine decarboxylase (EC 4.1.1.18) from Selenomonas ruminantium
PFams: Ala_racemase_N, Orn_Arg_deC_N, Orn_DAP_Arg_deC
393 amino acids: PaperBLAST, CDD