Clusters of Characterized Proteins

Clustering the characterized proteins for malEIICBA (maltose phosphotransferase system, EII-CBA components) in D-maltose catabolism

Or see other characterized proteins similar to malEIICBA

Or see all steps for D-maltose catabolism

Or cluster curated proteins matching a keyword

Definition of malEIICBA

• Curated sequence Q48WG5: Maltose/Maltotriose PTS transporter, MalT (Shelburne et al., 2008) 631aas (68% identical to 4.A.1.1.11 from S. mutans
• Curated sequence Q8DS05: The maltose/maltotriose porter, MalT (31% identical to 4.A.1.1.9)
• UniProt sequence Q836Y6: SubName: Full=PTS system, IIABC components {ECO:0000313|EMBL:AAO80765.1};
• Ignore hits to Q63GK8 when looking for 'other' hits (The Maltose group translocator, MalT of 470 aas and 10 TMSs. Takes up extracellular maltose, releasing maltose-phosphate into the cytoplasm)
• Comment: Streptococcus mutans and Streptococcus pyogenes have a EII-CBA system malT. A related system in Enterococcus faecalis (EF0958 = Q836Y6) was also shown to be a PTS sytem for maltose (PMID:15752325). The EII-CB portion of these proteins is similar to the EII-CB portion of B. subtilis, so that is marked ignore.

Fetched 3 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 3 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 631-729 amino acids (not heteromeric)

TC 4.A.1.1.12 / Q48WG5 Maltose/Maltotriose PTS transporter, MalT (Shelburne et al., 2008) 631aas (68% identical to 4.A.1.1.11 from S. mutans from Streptococcus pyogenes serotype M1
PFams: PTS_EIIC, PTS_EIIB, PTS_EIIA_1
631 amino acids: PaperBLAST, CDD, Compare to cluster

TC 4.A.1.1.11 / Q8DS05 The maltose/maltotriose porter, MalT (31% identical to 4.A.1.1.9) from Streptococcus mutans
PFams: PTS_EIIC, PTS_EIIB, PTS_EIIA_1
729 amino acids: PaperBLAST, CDD, Compare to cluster

Q836Y6 PTS system, IIABC components
722 amino acids: PaperBLAST, CDD, Compare to cluster