Clusters of Characterized Proteins

Clustering the characterized proteins for cmtA (mannitol phosphotransferase system, EII-CB component CmtA/MtlF) in D-mannitol catabolism

Or see other characterized proteins similar to cmtA

Or see all steps for D-mannitol catabolism

Or cluster curated proteins matching a keyword

Definition of cmtA

• Curated sequence P69826: PTS system mannitol-specific cryptic EIICB component; EIICB-Mtl; EII-Mtl; EC 2.7.1.197. EIICB-Mtl. mannitol-specific PTS enzyme IICB component CmtA (EC 2.7.1.197). mannitol-specific PTS enzyme IICB component CmtA (EC 2.7.1.197)
• Curated sequence P42956: PTS system, mannitol-specific IICBA component aka EIICBA-Mtl aka Mannitol-permease IIABC component aka Phosphotransferase enzyme II, CBA component aka EC 2.7.1.69 aka EII-Mtl, component of The mannitol porter (MtlA) (mannitol-1-P forming), MtlAF
• Curated sequence P28008: PTS system mannitol-specific EIICB component; EIICB-Mtl; EII-Mtl; EC 2.7.1.197
• Curated sequence O65989: PTS system mannitol-specific EIICB component; EIICB-Mtl; EII-Mtl; EC 2.7.1.197
• Curated sequence P50852: PTS system mannitol-specific EIICB component; EIICB-Mtl; EII-Mtl; EC 2.7.1.197
• Ignore hits to P00550 when looking for 'other' hits (protein-Npi-phosphohistidine-D-mannitol phosphotransferase (EC 2.7.1.197). PTS system mannitol-specific EIICBA component; EC 2.7.1.-; EC 2.7.1.69. PTS system mannitol-specific EIICBA component; EIICBA-Mtl; EII-Mtl; EC 2.7.1.197. Mannitol porter (MtlA) (mannitol-1-P forming), the mannitol IICBA complex. mannitol-specific PTS enzyme IICBA component (EC 2.7.1.197; EC 2.7.1.198). mannitol-specific PTS enzyme IICBA component (EC 2.7.1.197; EC 2.7.1.198))
• Ignore hits to Q9KKQ7 when looking for 'other' hits (The mannitol/glucitol transporter, MtlA (IICBAMtl))
• Comment: Two-part PTS, with EII-CB (cmtA/mtlA) separate from EII-A (cmtB/mtlF), in Escherichia coli (cmt system), Bacillus subtilis, Staphylococcus carnosus, Clostridium acetobutylicum, and Geobacillus stearothermophilus. Ignore similarity to the unified systems.

Fetched 5 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 5 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 462-518 amino acids (2/5 heteromeric)

PTMCB_CLOAB / O65989 PTS system mannitol-specific EIICB component; EIICB-Mtl; EII-Mtl; EC 2.7.1.197 from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787)
PFams: PTS_EIIC, PTS_IIB
481 amino acids: PaperBLAST, CDD, Compare to cluster

PTMCB_STACA / P28008 PTS system mannitol-specific EIICB component; EIICB-Mtl; EII-Mtl; EC 2.7.1.197 from Staphylococcus carnosus
PFams: PTS_EIIC, PTS_IIB
518 amino acids: PaperBLAST, CDD, Compare to cluster

PTMCB_GEOSE / P50852 PTS system mannitol-specific EIICB component; EIICB-Mtl; EII-Mtl; EC 2.7.1.197 from Geobacillus stearothermophilus (Bacillus stearothermophilus)
PFams: PTS_EIIC, PTS_IIB
471 amino acids: PaperBLAST, CDD, Compare to cluster

b2933 mannitol-specific PTS enzyme IICB component CmtA (EC 2.7.1.197) from Escherichia coli K-12 substr. MG1655
P69826 mannitol-specific PTS enzyme IICB component CmtA (EC 2.7.1.197) from Escherichia coli (strain K12)
PTMCB_ECOLI / P69826 PTS system mannitol-specific cryptic EIICB component; EIICB-Mtl; EII-Mtl; EC 2.7.1.197 from Escherichia coli (strain K12)
RF|NP_417408 EIICB-Mtl from Escherichia coli K12
PFams: PTS_EIIC, PTS_IIB
Heteromeric, 462 amino acids: PaperBLAST, CDD, Compare to cluster

TC 4.A.2.1.5 / P42956 PTS system, mannitol-specific IICBA component aka EIICBA-Mtl aka Mannitol-permease IIABC component aka Phosphotransferase enzyme II, CBA component aka EC 2.7.1.69 aka EII-Mtl, component of The mannitol porter (MtlA) (mannitol-1-P forming), MtlAF from Bacillus subtilis
PFams: PTS_EIIC, PTS_IIB
Heteromeric, 478 amino acids: PaperBLAST, CDD, Compare to cluster