Clusters of Characterized Proteins

Clustering the characterized proteins for mtlE (polyol ABC transporter, substrate-binding component MtlE/SmoE) in D-mannitol catabolism

Or see other characterized proteins similar to mtlE

Or see all steps for D-mannitol catabolism

Or cluster curated proteins matching a keyword

Definition of mtlE

• Curated sequence O30491: MtlE, component of The polyol (mannitol, glucitol (sorbitol), arabitol (arabinitol; lyxitol)) uptake porter, MtlEFGK
• Curated sequence GFF2493: ABC transporter for D-Mannitol, D-Mannose, and D-Sorbitol, periplasmic substrate-binding protein
• Curated sequence PfGW456L13_3042: ABC transporter for D-Mannitol, D-Mannose, and D-Mannose, periplasmic substrate-binding component
• Curated sequence AO353_25880: ABC transporter for D-mannitol and D-mannose, periplasmic substrate-binding component
• Ignore hits to AO356_00025 when looking for 'other' hits (ABC transporter for D-Sorbitol, periplasmic substrate-binding component)
• Ignore hits to Pf6N2E2_1963 when looking for 'other' hits (ABC transporter for D-sorbitol, periplasmic substrate-binding component)
• Curated sequence O30831: SmoE, component of Hexitol (glucitol; mannitol) porter
• Comment: MtlEFGK in several strains of Pseudomonas fluorescens or Pseudomonas simiae, or smoEFGK in Rhodopseudomonas sphaeroides. (The Rhodopseudomonas system was missed by the query; it is annotated as a hexitol transporter.) For all components, ignore simlarity to close homologs in FW300-N2C3 or FW300-N2E2, annotated as transporting sorbitol only.

Fetched 5 sequences

Running BLASTp

Found similarities, at above 30% identity and 75% coverage, for 5 of these sequences

Found 1 clusters of similar sequences. Download as table or as draft rules or view by organism

Cluster 1 436-440 amino acids (4/5 heteromeric)

TC 3.A.1.1.49 / O30491 MtlE, component of The polyol (mannitol, glucitol (sorbitol), arabitol (arabinitol; lyxitol)) uptake porter, MtlEFGK from Pseudomonas fluorescens
PFams: SBP_bac_1, SBP_bac_8
Heteromeric, 436 amino acids: PaperBLAST, CDD, Compare to cluster

TC 3.A.1.1.5 / O30831 SmoE, component of Hexitol (glucitol; mannitol) porter from Rhodobacter sphaeroides (Rhodopseudomonas sphaeroides)
PFams: SBP_bac_1, SBP_bac_8
Heteromeric, 436 amino acids: PaperBLAST, CDD, Compare to cluster

PS417_12715 ABC transporter for D-Mannitol, D-Mannose, and D-Sorbitol, periplasmic substrate-binding protein from Pseudomonas simiae WCS417
PFams: SBP_bac_1, SBP_bac_8
440 amino acids: PaperBLAST, CDD, Compare to cluster

PfGW456L13_3042 ABC transporter for D-Mannitol, D-Mannose, and D-Mannose, periplasmic substrate-binding component from Pseudomonas fluorescens GW456-L13
PFams: SBP_bac_1, SBP_bac_8
Heteromeric, 436 amino acids: PaperBLAST, CDD, Compare to cluster

AO353_25880 ABC transporter for D-mannitol and D-mannose, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2E3
PFams: SBP_bac_1, SBP_bac_8
Heteromeric, 436 amino acids: PaperBLAST, CDD, Compare to cluster